Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP25
  • Mouse genes Usp25
  • Rat genes Usp25
  • Zfish genes usp25
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp25

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	USP25	IPI	UniProtKB:P55072	Human	PMID:22590560
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP25	IMP		Human	PMID:18538659
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P55854	Human	PMID:18538659
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P43405	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:O15481	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P43405	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54725	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P61956	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:Q9BUY5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54727	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54725	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P43405	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P61956	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:Q3MIT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:Q9BTV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P43405	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P54725	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P0DTD1:PRO_0000449633	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	USP25	IPI	UniProtKB:P0DTD1:PRO_0000449633	Human	PMID:34232536
Molecular Function	GO:0032183	SUMO binding	USP25	IPI	UniProtKB:P63165	Human	PMID:18538659
Molecular Function	GO:0031625	ubiquitin protein ligase binding	USP25	IPI	UniProtKB:Q86TM6	Human	PMID:22590560
Cellular Component	GO:0005829	cytosol	USP25	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	USP25	IDA		Human	PMID:22590560
Biological Process	GO:0032602	chemokine production	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:1904888	cranial skeletal system development	usp25	IMP	ZFIN:ZDB-MRPHLNO-100217-17	Zfish	PMID:28450118
Biological Process	GO:0001816	cytokine production	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:0009953	dorsal/ventral pattern formation	usp25	IMP	ZFIN:ZDB-MRPHLNO-100217-17	Zfish	PMID:20040115
Biological Process	GO:0007252	I-kappaB phosphorylation	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:0006955	immune response	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Usp25	IDA		Mouse	PMID:23042150
Biological Process	GO:0016071	mRNA metabolic process	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150
Biological Process	GO:1904293	negative regulation of ERAD pathway	USP25	IMP		Human	PMID:22590560
Biological Process	GO:0016579	protein deubiquitination	USP25	IDA		Human	PMID:22590560
Biological Process	GO:0071108	protein K48-linked deubiquitination	USP25	IMP		Human	PMID:18538659
Biological Process	GO:0070536	protein K63-linked deubiquitination	USP25	IMP		Human	PMID:18538659
Biological Process	GO:0006979	response to oxidative stress	Usp25	IMP		Mouse	PMID:23453926
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	Usp25	IMP	MGI:MGI:4332130	Mouse	PMID:23042150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern