Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP27X
  • Mouse genes Usp27x
  • Rat genes Usp27x
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp27x

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP27X	IDA		Human	PMID:31534008
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP27X	IDA		Human	PMID:32027733
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Molecular Function	GO:0005515	protein binding	Usp27x	IPI	UniProtKB:O54918	Mouse	MGI:MGI:5796064|PMID:27013495
Biological Process	GO:0051607	defense response to virus	USP27X	IMP		Human	PMID:31534008
Biological Process	GO:0043065	positive regulation of apoptotic process	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	USP27X	IDA		Human	PMID:31534008
Biological Process	GO:0016579	protein deubiquitination	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Biological Process	GO:0071108	protein K48-linked deubiquitination	USP27X	IDA		Human	PMID:31534008
Biological Process	GO:0071108	protein K48-linked deubiquitination	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Biological Process	GO:0070536	protein K63-linked deubiquitination	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495
Biological Process	GO:0050821	protein stabilization	USP27X	IDA		Human	PMID:31534008
Biological Process	GO:0050821	protein stabilization	Usp27x	IDA		Mouse	MGI:MGI:5796064|PMID:27013495

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern