Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP3
  • Mouse genes Usp3
  • Rat genes Usp3
  • Zfish genes usp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP3	IMP		Human	PMID:17980597
Molecular Function	GO:0042393	histone binding	USP3	IPI	UniProtKB:P0C0S8	Human	PMID:17980597
Molecular Function	GO:1990841	promoter-specific chromatin binding	Usp3	IDA		Rat	PMID:16279867|RGD:8657120
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Usp3	IDA		Rat	PMID:16279867|RGD:8657120
Cellular Component	GO:0000785	chromatin	USP3	IDA		Human	PMID:17980597
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	USP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090543	Flemming body	USP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	USP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Usp3	IDA		Rat	PMID:16279867|RGD:8657120
Biological Process	GO:0006281	DNA repair	USP3	IMP		Human	PMID:17980597
Biological Process	GO:0016578	histone deubiquitination	USP3	IDA		Human	PMID:17980597
Biological Process	GO:0000278	mitotic cell cycle	USP3	IMP		Human	PMID:17980597
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Usp3	IDA		Rat	PMID:16279867|RGD:8657120
Biological Process	GO:0031647	regulation of protein stability	USP3	IDA		Human	PMID:17980597

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern