Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP47
  • Mouse genes Usp47
  • Rat genes Usp47
  • Zfish genes usp47
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp47

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP47	IDA		Human	PMID:21362556
Molecular Function	GO:0101005	deubiquitinase activity	USP47	IDA		Human	PMID:26169834
Molecular Function	GO:0005515	protein binding	USP47	IPI	UniProtKB:P06746	Human	PMID:21362556
Molecular Function	GO:0005515	protein binding	USP47	IPI	UniProtKB:O00189	Human	PMID:25416956
Molecular Function	GO:0071987	WD40-repeat domain binding	USP47	IPI	UniProtKB:Q9UKB1	Human	PMID:19966869
Molecular Function	GO:0071987	WD40-repeat domain binding	USP47	IPI	UniProtKB:Q9Y297	Human	PMID:19966869
Cellular Component	GO:0005737	cytoplasm	USP47	IDA		Human	PMID:21362556
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	USP47	IDA		Human	PMID:19966869
Biological Process	GO:0006284	base-excision repair	USP47	IMP		Human	PMID:21362556
Biological Process	GO:0034644	cellular response to UV	Usp47	IMP		Mouse	MGI:MGI:4839431|PMID:19966869
Biological Process	GO:0006974	DNA damage response	USP47	IMP		Human	PMID:21362556
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Usp47	IMP	MGI:MGI:4130032	Mouse	PMID:19966869
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	USP47	IDA		Human	PMID:21362556
Biological Process	GO:0043066	negative regulation of apoptotic process	USP47	IMP		Human	PMID:19966869
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	USP47	IMP		Human	PMID:19966869
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	USP47	IMP		Human	PMID:19966869
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	USP47	IMP		Human	PMID:19966869
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Usp47	IMP	MGI:MGI:4130032	Mouse	PMID:19966869
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	USP47	IMP		Human	PMID:26169834
Biological Process	GO:0030307	positive regulation of cell growth	USP47	IMP		Human	PMID:19966869
Biological Process	GO:0009410	response to xenobiotic stimulus	USP47	IMP		Human	PMID:19966869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern