Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP5
  • Mouse genes Usp5
  • Rat genes Usp5
  • Zfish genes usp5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP5	IDA		Human	PMID:24424410
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP5	EXP		Human	PMID:26235645
Molecular Function	GO:0005515	protein binding	USP5	IPI	UniProtKB:O75528	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	USP5	IPI	UniProtKB:P54727	Human	PMID:16712842
Molecular Function	GO:0005515	protein binding	USP5	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP5	IPI	UniProtKB:Q8WW34	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Usp5	IPI	UniProtKB:Q8BVP1	Mouse	MGI:MGI:3852295|PMID:19156909
Molecular Function	GO:0005515	protein binding	Usp5	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0043130	ubiquitin binding	USP5	IDA		Human	PMID:24424410
Cellular Component	GO:0005737	cytoplasm	usp5	IDA		Zfish	PMID:32407768
Biological Process	GO:1904888	cranial skeletal system development	usp5	IMP	ZFIN:ZDB-MRPHLNO-100215-8	Zfish	PMID:28450118
Biological Process	GO:0009953	dorsal/ventral pattern formation	usp5	IMP	ZFIN:ZDB-MRPHLNO-100215-8	Zfish	PMID:20040115
Biological Process	GO:0045071	negative regulation of viral genome replication	usp5	IDA		Zfish	PMID:32407768
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	USP5	IMP		Human	PMID:19098288
Biological Process	GO:0016579	protein deubiquitination	USP5	IDA		Human	PMID:24424410
Biological Process	GO:0071108	protein K48-linked deubiquitination	USP5	IMP		Human	PMID:19098288

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern