Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP9X
  • Mouse genes Usp9x
  • Rat genes Usp9x
  • Zfish genes usp9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp9x

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070410	co-SMAD binding	USP9X	IPI	UniProtKB:Q13485	Human	PMID:19135894
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP9X	EXP		Human	PMID:22371489
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP9X	IDA		Human	PMID:22371489
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP9X	EXP		Human	PMID:26235645
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Usp9x	IDA		Mouse	MGI:MGI:6293949|PMID:30951545
Molecular Function	GO:0101005	deubiquitinase activity	Usp9x	IDA		Mouse	MGI:MGI:6162398|PMID:18410486
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	USP9X	IDA		Human	PMID:25944111
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	USP9X	IDA		Human	PMID:33378666
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:O60285	Human	PMID:16306228
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:O15392	Human	PMID:16322459
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:Q13485	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:Q07820	Human	PMID:20023629
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:O43602	Human	PMID:24607389
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:P08393	Human	PMID:26596467
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:O00327	Human	PMID:29626158
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:O60285	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	USP9X	IPI	UniProtKB:Q6R327	Human	PMID:33378666
Molecular Function	GO:0005515	protein binding	Usp9x	IPI	UniProtKB:A5PKW4	Mouse	MGI:MGI:5508566|PMID:20339350
Molecular Function	GO:0005515	protein binding	Usp9x	IPI	UniProtKB:Q13485	Mouse	MGI:MGI:4365323|PMID:19135894
Molecular Function	GO:0005515	protein binding	Usp9x	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:6157201|PMID:29626158
Molecular Function	GO:0005515	protein binding	Usp9x	IPI	PR:P42859	Mouse	PMID:17500595
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Usp9x	IPI	UniProtKB:Q9WV66	Mouse	MGI:MGI:6162398|PMID:18410486
Cellular Component	GO:0045177	apical part of cell	Usp9x	IDA		Mouse	PMID:10704870
Cellular Component	GO:0005929	cilium	USP9X	IDA		Human	PMID:26833328
Cellular Component	GO:0005737	cytoplasm	USP9X	IDA		Human	PMID:19135894
Cellular Component	GO:0005737	cytoplasm	Usp9x	IDA		Mouse	PMID:15509704
Cellular Component	GO:0005829	cytosol	USP9X	IDA		Human	PMID:22371489
Cellular Component	GO:0005829	cytosol	USP9X	IDA		Human	PMID:18410486
Cellular Component	GO:0030426	growth cone	USP9X	IDA		Human	PMID:24607389
Cellular Component	GO:0016020	membrane	USP9X	HDA		Human	PMID:19946888
Biological Process	GO:0048675	axon extension	USP9X	IMP		Human	PMID:24607389
Biological Process	GO:0048675	axon extension	Usp9x	IMP		Mouse	MGI:MGI:5574428|PMID:24607389
Biological Process	GO:0048675	axon extension	Usp9x	IMP	MGI:MGI:5438072	Mouse	PMID:23861879
Biological Process	GO:0030509	BMP signaling pathway	USP9X	IDA		Human	PMID:19135894
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Usp9x	IMP	MGI:MGI:5438072	Mouse	PMID:23861879
Biological Process	GO:0021698	cerebellar cortex structural organization	Usp9x	IMP	MGI:MGI:5438072	Mouse	PMID:23861879
Biological Process	GO:0021766	hippocampus development	Usp9x	IMP	MGI:MGI:5438072	Mouse	PMID:23861879
Biological Process	GO:0001701	in utero embryonic development	Usp9x	IGI	MGI:MGI:95387	Mouse	PMID:23861879
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	USP9X	IDA		Human	PMID:22371489
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	USP9X	IMP		Human	PMID:33378666
Biological Process	GO:0001764	neuron migration	USP9X	IMP		Human	PMID:24607389
Biological Process	GO:0001764	neuron migration	Usp9x	IMP		Mouse	MGI:MGI:5574428|PMID:24607389
Biological Process	GO:1990138	neuron projection extension	Usp9x	IGI	MGI:MGI:95387	Mouse	PMID:23861879
Biological Process	GO:1901537	positive regulation of DNA demethylation	USP9X	IDA		Human	PMID:25944111
Biological Process	GO:0032092	positive regulation of protein binding	USP9X	IMP		Human	PMID:33378666
Biological Process	GO:1904515	positive regulation of TORC2 signaling	USP9X	IDA		Human	PMID:33378666
Biological Process	GO:0009791	post-embryonic development	Usp9x	IMP	MGI:MGI:5438072	Mouse	PMID:23861879
Biological Process	GO:0016579	protein deubiquitination	USP9X	IDA		Human	PMID:19135894
Biological Process	GO:0016579	protein deubiquitination	Usp9x	IMP		Mouse	MGI:MGI:6162398|PMID:18410486
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	USP9X	IMP		Human	PMID:29626158
Biological Process	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	Usp9x	IMP		Mouse	MGI:MGI:6157201|PMID:29626158
Biological Process	GO:0016562	protein import into peroxisome matrix, receptor recycling	USP9X	IDA		Human	PMID:22371489
Biological Process	GO:0070536	protein K63-linked deubiquitination	USP9X	IDA		Human	PMID:33378666
Biological Process	GO:0050821	protein stabilization	USP9X	IMP		Human	PMID:18410486
Biological Process	GO:0050821	protein stabilization	USP9X	IMP		Human	PMID:33378666
Biological Process	GO:0042752	regulation of circadian rhythm	USP9X	IMP		Human	PMID:29626158
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	USP9X	IMP		Human	PMID:19135894

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern