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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Vamp2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vamp2
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0048306calcium-dependent protein bindingVamp2IPIUniProtKB:P21707RatPMID:12526776|RGD:10047386
Molecular FunctionGO:0005516calmodulin bindingVamp2IDAMousePMID:12145198
Molecular FunctionGO:0042802identical protein bindingVamp2IPIUniProtKB:P63045RatPMID:21856303|RGD:8554367
Molecular FunctionGO:0008289lipid bindingVamp2EXPRatPMID:19918058|RGD:152995573
Molecular FunctionGO:0060090molecular adaptor activityVamp2EXPRatPMID:19918058|RGD:152995573
Molecular FunctionGO:0017022myosin bindingVamp2IPIRGD:3143RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0005543phospholipid bindingVamp2IDAMousePMID:12145198
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q16623HumanPMID:10481273
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:O94806HumanPMID:17196367
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P41743HumanPMID:17313651
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q05513HumanPMID:17313651
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q96P53HumanPMID:17313651
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P53675HumanPMID:19478182
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q57236HumanPMID:19543288
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P37840HumanPMID:20798282
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q16623HumanPMID:20798282
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:O55012HumanPMID:22118466
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q13492HumanPMID:22118466
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:A7GBG3HumanPMID:22172278
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:D2KHQ9HumanPMID:22172278
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:O95721HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q12846HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q16623HumanPMID:26635000
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P31937HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P32856-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P61266HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q12846HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q13520HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q15125HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q16623HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q3SXY8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q3ZAQ7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q5T0T0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q7Z5P4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q8IWU4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q8N5M9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q8N661HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q8N6L0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q8TBB6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q96BA8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q96IK0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q9HA82HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q9NY72HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:Q9Y282HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:P55072HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingVAMP2IPIUniProtKB:O95292HumanPMID:9920726
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:B0BNF1|UniProtKB:P07825|UniProtKB:P32851|UniProtKB:P60881MouseMGI:MGI:6245748|PMID:19196426
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:5618598|PMID:24705552
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:3703199|PMID:17283335
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q9ES83MouseMGI:MGI:4431297|PMID:20057356
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60766MouseMGI:MGI:4441124|PMID:15537656
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:5919808|PMID:16565726
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:O35526MouseMGI:MGI:6294198|PMID:24356748
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q155P7MouseMGI:MGI:3814962|PMID:18827011
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:6092627|PMID:19805029
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:5314486|PMID:22187053
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:4431150|PMID:20114047
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:5508581|PMID:19703397
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q02956|UniProtKB:Q62074|UniProtKB:Q8BUB4MouseMGI:MGI:5693229|PMID:17313651
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60879MouseMGI:MGI:4830915|PMID:20798282
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:P60879MousePMID:21040848
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:P70452MousePMID:10394363
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:Q62277MousePMID:18706977
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:P70452MousePMID:19188424
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:P28663MousePMID:21040848
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:Q9DB05MousePMID:21040848
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:Q64704MousePMID:18505797
Molecular FunctionGO:0005515protein bindingVamp2IPIPR:O35526MousePMID:21040848
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q8CFN2RatPMID:15537656|RGD:8554063
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:D4A229RatPMID:17196367|RGD:8554790
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q60770RatPMID:19116655|RGD:13825192
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60881-2RatPMID:19571812|RGD:13432305
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P21707RatPMID:20173763|RGD:13432278
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P32851RatPMID:21193638|RGD:13432275
Molecular FunctionGO:0005515protein bindingVamp2IPIRGD:621054RatPMID:21808019|RGD:13506237
Molecular FunctionGO:0005515protein bindingVamp2IPIRGD:69276RatPMID:21808019|RGD:13506237
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q08850RatPMID:23380067|RGD:10047320
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:Q08850RatPMID:24469400|RGD:10047308
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P32851RatPMID:25581794|RGD:13432311
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P60881-2RatPMID:25814585|RGD:13432338
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P21707RatPMID:8567678|RGD:2301258
Molecular FunctionGO:0005515protein bindingVamp2IPIUniProtKB:P32851RatPMID:8567678|RGD:2301258
Molecular FunctionGO:0005515protein bindingVamp2IPIRGD:621002RatPMID:9341137|RGD:633794
Molecular FunctionGO:0044877protein-containing complex bindingVamp2IPIRGD:3802|RGD:1306159RatPMID:8567678|RGD:2301258
Molecular FunctionGO:0000149SNARE bindingVamp2IDAMousePMID:12145198
Molecular FunctionGO:0000149SNARE bindingVamp2IPIUniProtKB:P32851,UniProtKB:P60881RatPMID:12680753|RGD:12793015
Molecular FunctionGO:0000149SNARE bindingVamp2IDARatPMID:7553862|RGD:70701
Molecular FunctionGO:0000149SNARE bindingVamp2IPIUniProtKB:P32851,UniProtKB:P60881RatPMID:9671503|RGD:12793053
Molecular FunctionGO:0019905syntaxin bindingVAMP2IPIUniProtKB:Q12846HumanPMID:12855681
Molecular FunctionGO:0019905syntaxin bindingVamp2IPIUniProtKB:P70452MouseMGI:MGI:4457249|PMID:17548353
Molecular FunctionGO:0017075syntaxin-1 bindingVamp2IDAMouseMGI:MGI:3803800|PMID:18703708
Molecular FunctionGO:0017075syntaxin-1 bindingVamp2IPIRGD:69430RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0017075syntaxin-1 bindingVamp2IDARatPMID:7553862|RGD:70701
Molecular FunctionGO:0044325transmembrane transporter bindingVamp2IPIUniProtKB:P15387RatPMID:19077057|RGD:10047372
Molecular FunctionGO:0044325transmembrane transporter bindingVamp2IPIUniProtKB:P15387RatPMID:19690160|RGD:10047295
Cellular ComponentGO:0030136clathrin-coated vesicleVAMP2IDAHumanPMID:19478182
Cellular ComponentGO:0032154cleavage furrowvamp2IDAZfishPMID:16876784
Cellular ComponentGO:0032154cleavage furrowvamp2IDAZfishPMID:18313658
Cellular ComponentGO:0005737cytoplasmVamp2IDAMouseMGI:MGI:6294198|PMID:24356748
Cellular ComponentGO:0031410cytoplasmic vesicleVamp2IDAMousePMID:18505797
Cellular ComponentGO:0030659cytoplasmic vesicle membraneVamp2IDAMousePMID:12490950
Cellular ComponentGO:0043231intracellular membrane-bounded organelleVamp2IDARatPMID:10051443|RGD:634161
Cellular ComponentGO:0043229intracellular organelleVamp2IDARatPMID:10340764|RGD:4892571
Cellular ComponentGO:0016020membraneVAMP2IDAHumanPMID:16677249
Cellular ComponentGO:0016020membraneVAMP2IDAHumanPMID:22375059
Cellular ComponentGO:0043005neuron projectionVamp2IDARatPMID:8567678|RGD:2301258
Cellular ComponentGO:0044306neuron projection terminusVamp2IDARatPMID:10908612|RGD:634537
Cellular ComponentGO:0048471perinuclear region of cytoplasmVamp2IDAMouseMGI:MGI:3814962|PMID:18827011
Cellular ComponentGO:0005886plasma membraneVamp2IDAMousePMID:18505797
Cellular ComponentGO:0005886plasma membraneVamp2IDAMousePMID:21828338
Cellular ComponentGO:0005886plasma membraneVamp2IDARatPMID:10051443|RGD:634161
Cellular ComponentGO:0005886plasma membraneVamp2IDARatPMID:15537656|RGD:8554063
Cellular ComponentGO:0005886plasma membraneVamp2IDARatPMID:19690160|RGD:10047295
Cellular ComponentGO:0005886plasma membranevamp2IDAZfishPMID:16876784
Cellular ComponentGO:0030141secretory granuleVamp2IDAMouseMGI:MGI:6294198|PMID:24356748
Cellular ComponentGO:0030141secretory granuleVamp2IDAMousePMID:12145198
Cellular ComponentGO:0030141secretory granuleVamp2IDARatPMID:15537656|RGD:8554063
Cellular ComponentGO:0031201SNARE complexVAMP2IDAHumanPMID:12130530
Cellular ComponentGO:0031201SNARE complexVAMP2IDAHumanPMID:12730201
Cellular ComponentGO:0031201SNARE complexVAMP2IDAHumanPMID:19546860
Cellular ComponentGO:0031201SNARE complexVamp2IDAMousePMID:18535671
Cellular ComponentGO:0031201SNARE complexVamp2IDARatPMID:10051443|RGD:634161
Cellular ComponentGO:0031201SNARE complexVamp2IDARatPMID:16030255|RGD:1581734
Cellular ComponentGO:0031201SNARE complexVamp2IDARatPMID:23949442|RGD:8553762
Cellular ComponentGO:0000322storage vacuoleVamp2IDAMousePMID:21828338
Cellular ComponentGO:0045202synapseVamp2IDAMousePMID:18706977
Cellular ComponentGO:0045202synapseVamp2IDAMousePMID:20943658
Cellular ComponentGO:0045202synapseVamp2IDAMousePMID:24794856
Cellular ComponentGO:0045202synapseVamp2IDAMousePMID:23791195
Cellular ComponentGO:0008021synaptic vesicleVamp2IDAMousePMID:15145078
Cellular ComponentGO:0008021synaptic vesicleVamp2IDARatPMID:10908612|RGD:634537
Cellular ComponentGO:0008021synaptic vesicleVamp2IDARatPMID:17110340|RGD:12050113
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2IDAMousePMID:12192047
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2IDAMousePMID:15071120
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2EXPRatPMID:17110340|RGD:12050113
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2IDARatPMID:17110340|RGD:12050113
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2IDARatPMID:30703389|RGD:155230780
Cellular ComponentGO:0030672synaptic vesicle membraneVamp2IDARatPMID:23792689|RGD:12793033
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexVamp2IDAMousePMID:21040848
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexVamp2IDARatPMID:22711810|RGD:7205652
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexVamp2IMPRatPMID:12680753|RGD:12793015
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexVamp2IDARatPMID:7553862|RGD:70701
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexVamp2IMPRatPMID:9671503|RGD:12793053
Cellular ComponentGO:0070032synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complexVamp2IDARatPMID:7553862|RGD:70701
Cellular ComponentGO:0070033synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complexVamp2IDARatPMID:19132534|RGD:7205655
Cellular ComponentGO:0043195terminal boutonVamp2HDARatPMID:24876496|RGD:10047219
Cellular ComponentGO:0005802trans-Golgi networkVamp2IDAMouseMGI:MGI:3814962|PMID:18827011
Cellular ComponentGO:0031982vesicleVAMP2IDAHumanPMID:17313651
Cellular ComponentGO:0031982vesicleVamp2IDAMouseMGI:MGI:5693229|PMID:17313651
Cellular ComponentGO:0031982vesiclevamp2IDAZfishPMID:16876784
Cellular ComponentGO:0031982vesiclevamp2IDAZfishPMID:18313658
Cellular ComponentGO:0042589zymogen granule membraneVamp2IDAMousePMID:12192047
Biological ProcessGO:0017156calcium-ion regulated exocytosisVamp2IMPMGI:MGI:2179745MousePMID:15920476
Biological ProcessGO:0017156calcium-ion regulated exocytosisVamp2IDAMousePMID:12145198
Biological ProcessGO:0032869cellular response to insulin stimulusVamp2IDAMousePMID:18227281
Biological ProcessGO:0043308eosinophil degranulationVAMP2IMPHumanPMID:16677249
Biological ProcessGO:0051649establishment of localization in cellVamp2IMPMGI:MGI:2179745MousePMID:15920476
Biological ProcessGO:0098967exocytic insertion of neurotransmitter receptor to postsynaptic membraneVamp2IMPMouseMGI:MGI:5494785|PMID:23395379
Biological ProcessGO:0098967exocytic insertion of neurotransmitter receptor to postsynaptic membraneVamp2IMPRatPMID:26839408|RGD:12050145
Biological ProcessGO:0043001Golgi to plasma membrane protein transportVamp2IMPMousePMID:20582536
Biological ProcessGO:0046879hormone secretionVamp2IDAMouseMGI:MGI:6294198|PMID:24356748
Biological ProcessGO:0060291long-term synaptic potentiationVamp2IMPMousePMID:23395379
Biological ProcessGO:0061025membrane fusionVamp2IMPMGI:MGI:2179745MousePMID:15920476
Biological ProcessGO:0090316positive regulation of intracellular protein transportVamp2IMPMousePMID:18227281
Biological ProcessGO:0015031protein transportVamp2IMPRatPMID:11245593|RGD:2306548
Biological ProcessGO:0065003protein-containing complex assemblyVamp2IDARatPMID:10051443|RGD:634161
Biological ProcessGO:0045055regulated exocytosisVamp2IDAMouseMGI:MGI:6294198|PMID:24356748
Biological ProcessGO:1902259regulation of delayed rectifier potassium channel activityVamp2IDARatPMID:19690160|RGD:10047295
Biological ProcessGO:0017157regulation of exocytosisVamp2IDAMousePMID:12145198
Biological ProcessGO:0017157regulation of exocytosisVamp2IMPRatPMID:11245593|RGD:2306548
Biological ProcessGO:1903421regulation of synaptic vesicle recyclingVamp2IMPRatPMID:21808019|RGD:13506237
Biological ProcessGO:0060627regulation of vesicle-mediated transportVamp2IMPMousePMID:18227281
Biological ProcessGO:0009749response to glucoseVamp2IDARatPMID:15537656|RGD:8554063
Biological ProcessGO:0035493SNARE complex assemblyVamp2IMPRatPMID:12680753|RGD:12793015
Biological ProcessGO:0035493SNARE complex assemblyVamp2IMPRatPMID:9671503|RGD:12793053
Biological ProcessGO:0016081synaptic vesicle dockingVamp2IDAMousePMID:25374362
Biological ProcessGO:0016081synaptic vesicle dockingVamp2IMPMousePMID:25374362
Biological ProcessGO:0048488synaptic vesicle endocytosisVamp2IMPMouseMGI:MGI:3573806|PMID:15475946
Biological ProcessGO:0016079synaptic vesicle exocytosisVamp2IMPMouseMGI:MGI:3573806|PMID:15475946
Biological ProcessGO:0016079synaptic vesicle exocytosisVamp2IMPMGI:MGI:2179745MousePMID:11691998
Biological ProcessGO:0016079synaptic vesicle exocytosisVamp2IDARatPMID:1331807|RGD:13702243
Biological ProcessGO:0016079synaptic vesicle exocytosisVamp2IEPRatPMID:1331807|RGD:13702243
Biological ProcessGO:0016079synaptic vesicle exocytosisVamp2IMPRatPMID:1331807|RGD:13702243
Biological ProcessGO:0006906vesicle fusionVAMP2IMPHumanPMID:30929742
Biological ProcessGO:0016192vesicle-mediated transportVamp2IMPRatPMID:11245593|RGD:2306548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory