Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Vamp7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes VAMP7
- Mouse genes Vamp7
- Rat genes Vamp7
- Zfish genes sybl1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vamp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VAMP7	IPI	UniProtKB:Q5I940	Human	PMID:16354670
Molecular Function	GO:0005515	protein binding	VAMP7	IPI	UniProtKB:P52594	Human	PMID:18775314
Molecular Function	GO:0005515	protein binding	VAMP7	IPI	UniProtKB:Q5SQN1	Human	PMID:26359495
Molecular Function	GO:0005515	protein binding	VAMP7	IPI	UniProtKB:P0DTC3	Human	PMID:33845483
Molecular Function	GO:0005515	protein binding	VAMP7	IPI	UniProtKB:P0DTC3	Human	PMID:34706264
Molecular Function	GO:0005515	protein binding	Vamp7	IPI	UniProtKB:P56962	Mouse	MGI:MGI:5616306\|PMID:23217709
Molecular Function	GO:0005515	protein binding	Vamp7	IPI	UniProtKB:O88384\|UniProtKB:Q96NW4	Mouse	MGI:MGI:5918937\|PMID:23104059
Molecular Function	GO:0005515	protein binding	Vamp7	IPI	UniProtKB:Q3UMR0	Mouse	MGI:MGI:5607516\|PMID:21187829
Molecular Function	GO:0005515	protein binding	Vamp7	IPI	RGD:1307106	Rat	PMID:19745841\|RGD:8554110
Molecular Function	GO:0005515	protein binding	Vamp7	IPI	UniProtKB:Q96NW4	Rat	PMID:19745841\|RGD:8554110
Molecular Function	GO:0005484	SNAP receptor activity	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Molecular Function	GO:0019905	syntaxin binding	Vamp7	IPI	RGD:619747	Rat	PMID:15133481\|RGD:4892614
Cellular Component	GO:0045177	apical part of cell	Vamp7	IDA		Mouse	PMID:14758363
Cellular Component	GO:0035577	azurophil granule membrane	VAMP7	IDA		Human	PMID:16677249
Cellular Component	GO:0009986	cell surface	Vamp7	IDA		Mouse	MGI:MGI:5567905\|PMID:21151919
Cellular Component	GO:0005737	cytoplasm	VAMP7	IDA		Human	PMID:18253931
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Vamp7	IDA		Rat	PMID:16495485\|RGD:4892615
Cellular Component	GO:0070062	extracellular exosome	VAMP7	HDA		Human	PMID:19056867
Cellular Component	GO:0030175	filopodium	Vamp7	IDA		Rat	PMID:19745841\|RGD:8554110
Cellular Component	GO:0005794	Golgi apparatus	Vamp7	IDA		Mouse	PMID:18321981
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Vamp7	IDA		Rat	PMID:14596849\|RGD:13702238
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	VAMP7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030027	lamellipodium	VAMP7	IDA		Human	PMID:22589474
Cellular Component	GO:0030027	lamellipodium	Vamp7	IDA		Mouse	MGI:MGI:5444087\|PMID:22589474
Cellular Component	GO:0031902	late endosome membrane	Vamp7	IDA		Rat	PMID:10459012\|RGD:8554473
Cellular Component	GO:0031902	late endosome membrane	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Cellular Component	GO:0005765	lysosomal membrane	VAMP7	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	Vamp7	IDA		Rat	PMID:10459012\|RGD:8554473
Cellular Component	GO:0005765	lysosomal membrane	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Cellular Component	GO:0016020	membrane	VAMP7	IDA		Human	PMID:16677249
Cellular Component	GO:0043005	neuron projection	Vamp7	IDA		Mouse	MGI:MGI:5607233\|PMID:19745841
Cellular Component	GO:0043005	neuron projection	Vamp7	IDA		Mouse	MGI:MGI:5437407\|PMID:21998198
Cellular Component	GO:0043005	neuron projection	Vamp7	IDA		Rat	PMID:19745841\|RGD:8554110
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Vamp7	IDA		Mouse	PMID:18321981
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Vamp7	IDA		Rat	PMID:19745841\|RGD:8554110
Cellular Component	GO:0045335	phagocytic vesicle	Vamp7	IDA		Mouse	MGI:MGI:3799611\|PMID:15470500
Cellular Component	GO:0005886	plasma membrane	VAMP7	IDA		Human	PMID:18253931
Cellular Component	GO:0031091	platelet alpha granule	VAMP7	IDA		Human	PMID:22589474
Cellular Component	GO:0031143	pseudopodium	VAMP7	IDA		Human	PMID:22589474
Cellular Component	GO:0031143	pseudopodium	Vamp7	IDA		Mouse	MGI:MGI:5444087\|PMID:22589474
Cellular Component	GO:0030141	secretory granule	VAMP7	IDA		Human	PMID:18042464
Cellular Component	GO:0030667	secretory granule membrane	VAMP7	IDA		Human	PMID:16677249
Cellular Component	GO:0031201	SNARE complex	VAMP7	IDA		Human	PMID:18253931
Cellular Component	GO:0031201	SNARE complex	VAMP7	IDA		Human	PMID:24550300
Cellular Component	GO:0031201	SNARE complex	Vamp7	IDA		Rat	PMID:16735505\|RGD:4892613
Cellular Component	GO:0031201	SNARE complex	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Cellular Component	GO:0008021	synaptic vesicle	Vamp7	IDA		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Vamp7	IDA		Rat	PMID:14596849\|RGD:13702238
Cellular Component	GO:0030672	synaptic vesicle membrane	Vamp7	IDA		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0005802	trans-Golgi network	VAMP7	IDA		Human	PMID:19745841
Cellular Component	GO:0030133	transport vesicle	Vamp7	IDA		Mouse	MGI:MGI:5607233\|PMID:19745841
Biological Process	GO:0017156	calcium-ion regulated exocytosis	Vamp7	IDA		Rat	PMID:14993220\|RGD:8553828
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	Vamp7	IDA		Rat	PMID:16495485\|RGD:4892615
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	Vamp7	IDA		Rat	PMID:16735505\|RGD:4892613
Biological Process	GO:0008333	endosome to lysosome transport	VAMP7	IDA		Human	PMID:10888671
Biological Process	GO:0008333	endosome to lysosome transport	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Biological Process	GO:0043308	eosinophil degranulation	VAMP7	IMP		Human	PMID:16677249
Biological Process	GO:0043308	eosinophil degranulation	Vamp7	IDA		Rat	PMID:14993220\|RGD:8553828
Biological Process	GO:0006887	exocytosis	Vamp7	IDA		Rat	PMID:22705394\|RGD:10047362
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	Vamp7	IMP		Mouse	PMID:20582536
Biological Process	GO:0043320	natural killer cell degranulation	VAMP7	IMP		Human	PMID:18042464
Biological Process	GO:0043312	neutrophil degranulation	VAMP7	IMP		Human	PMID:16677249
Biological Process	GO:0043312	neutrophil degranulation	Vamp7	IDA		Rat	PMID:14993220\|RGD:8553828
Biological Process	GO:0006911	phagocytosis, engulfment	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Vamp7	IMP		Mouse	MGI:MGI:5490454\|PMID:22171327
Biological Process	GO:1903595	positive regulation of histamine secretion by mast cell	VAMP7	IMP		Human	PMID:18253931
Biological Process	GO:1900483	regulation of protein targeting to vacuolar membrane	Vamp7	IMP		Mouse	PMID:18227281
Biological Process	GO:0035493	SNARE complex assembly	Vamp7	IDA		Mouse	MGI:MGI:5567905\|PMID:21151919
Biological Process	GO:0034197	triglyceride transport	Vamp7	IMP		Rat	PMID:16495485\|RGD:4892615
Biological Process	GO:0006906	vesicle fusion	VAMP7	IDA		Human	PMID:10888671
Biological Process	GO:0006906	vesicle fusion	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614
Biological Process	GO:0048280	vesicle fusion with Golgi apparatus	Vamp7	IDA		Rat	PMID:16735505\|RGD:4892613
Biological Process	GO:0047496	vesicle transport along microtubule	Vamp7	IDA		Rat	PMID:22705394\|RGD:10047362
Biological Process	GO:0016192	vesicle-mediated transport	VAMP7	IDA		Human	PMID:10888671
Biological Process	GO:0016192	vesicle-mediated transport	Vamp7	IDA		Rat	PMID:15133481\|RGD:4892614

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.