Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VASH1
  • Mouse genes Vash1
  • Rat genes Vash1
  • Zfish genes vash1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vash1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	VASH1	IDA		Human	PMID:29146869
Molecular Function	GO:0003779	actin binding	Vash1	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH1	IDA		Human	PMID:29146869
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH1	IMP		Human	PMID:31171830
Molecular Function	GO:0004181	metallocarboxypeptidase activity	VASH1	IMP		Human	PMID:31235911
Molecular Function	GO:0004181	metallocarboxypeptidase activity	Vash1	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0005515	protein binding	VASH1	IPI	UniProtKB:P49366	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VASH1	IPI	UniProtKB:Q8N300	Human	PMID:29146869
Molecular Function	GO:0005515	protein binding	VASH1	IPI	UniProtKB:Q8N300	Human	PMID:31171830
Molecular Function	GO:0005515	protein binding	Vash1	IPI	UniProtKB:Q99LQ4	Mouse	MGI:MGI:6102981|PMID:29146868
Molecular Function	GO:0106423	tubulin-tyrosine carboxypeptidase	vash1	IMP	ZFIN:ZDB-MRPHLNO-211022-1	Zfish	PMID:33547133
Cellular Component	GO:0045177	apical part of cell	VASH1	IDA		Human	PMID:20736312
Cellular Component	GO:0005737	cytoplasm	VASH1	IDA		Human	PMID:15467828
Cellular Component	GO:0005783	endoplasmic reticulum	VASH1	IDA		Human	PMID:15467828
Cellular Component	GO:0005615	extracellular space	VASH1	IDA		Human	PMID:15467828
Cellular Component	GO:0005615	extracellular space	VASH1	IDA		Human	PMID:20133819
Cellular Component	GO:0005615	extracellular space	VASH1	IDA		Human	PMID:20736312
Biological Process	GO:0001525	angiogenesis	VASH1	IDA		Human	PMID:15467828
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Vash1	IMP	MGI:MGI:3846783	Mouse	PMID:25184477
Biological Process	GO:0001945	lymph vessel development	vash1	IMP	ZFIN:ZDB-CRISPR-211022-1	Zfish	PMID:33547133
Biological Process	GO:0001945	lymph vessel development	vash1	IMP	ZFIN:ZDB-MRPHLNO-211022-1	Zfish	PMID:33547133
Biological Process	GO:0016525	negative regulation of angiogenesis	VASH1	IGI	UniProtKB:Q00731	Human	PMID:20133819
Biological Process	GO:0016525	negative regulation of angiogenesis	VASH1	IDA		Human	PMID:15467828
Biological Process	GO:0016525	negative regulation of angiogenesis	Vash1	IDA		Mouse	PMID:19204325
Biological Process	GO:0016525	negative regulation of angiogenesis	Vash1	IMP	MGI:MGI:3846783	Mouse	PMID:19204325
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	VASH1	IDA		Human	PMID:15467828
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	VASH1	IDA		Human	PMID:19204325
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	VASH1	IDA		Human	PMID:15467828
Biological Process	GO:1901491	negative regulation of lymphangiogenesis	VASH1	IGI	UniProtKB:P97953	Human	PMID:20133819
Biological Process	GO:1901491	negative regulation of lymphangiogenesis	VASH1	IGI	UniProtKB:Q00731	Human	PMID:20133819
Biological Process	GO:0060674	placenta blood vessel development	Vash1	IMP	MGI:MGI:3846783	Mouse	PMID:25184477
Biological Process	GO:0006508	proteolysis	VASH1	IDA		Human	PMID:29146869
Biological Process	GO:0006508	proteolysis	Vash1	IDA		Mouse	MGI:MGI:6102981|PMID:29146868
Biological Process	GO:2000772	regulation of cellular senescence	VASH1	IMP		Human	PMID:23056314
Biological Process	GO:1903670	regulation of sprouting angiogenesis	vash1	IMP	ZFIN:ZDB-MRPHLNO-211022-1	Zfish	PMID:33547133
Biological Process	GO:0009611	response to wounding	VASH1	IDA		Human	PMID:23056314

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern