Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Vdac1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes VDAC1
- Mouse genes Vdac1
- Rat genes Vdac1
- Zfish genes vdac1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vdac1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097001	ceramide binding	VDAC1	IDA		Human	PMID:31015432
Molecular Function	GO:0015485	cholesterol binding	VDAC1	IDA		Human	PMID:31015432
Molecular Function	GO:0042802	identical protein binding	VDAC1	IPI	UniProtKB:P21796	Human	PMID:18832158
Molecular Function	GO:0005253	monoatomic anion channel activity	Vdac1	IDA		Rat	PMID:12438411\|RGD:634413
Molecular Function	GO:0031210	phosphatidylcholine binding	VDAC1	IDA		Human	PMID:31015432
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P0C0U1	Human	PMID:16201016
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P05141	Human	PMID:19130895
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P12236	Human	PMID:21370995
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q5S007	Human	PMID:21370995
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P19367	Human	PMID:22304920
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q7L3V2	Human	PMID:23055042
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q16611	Human	PMID:25296756
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:O75323\|UniProtKB:Q5SVS4	Human	PMID:26387735
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q9UQ90	Human	PMID:26387735
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P06493	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P12236	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P30041	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P45880	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P62258	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q9Y277	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q9Y277	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q5BJD5	Human	PMID:30352685
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:P51572	Human	PMID:31206022
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q07813	Human	PMID:9843949
Molecular Function	GO:0005515	protein binding	VDAC1	IPI	UniProtKB:Q16611	Human	PMID:9843949
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	UniProtKB:P50637	Mouse	MGI:MGI:5689082\|PMID:25470454
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	PR:Q9ER97	Mouse	PMID:22079573
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	RGD:2192	Rat	PMID:15044178\|RGD:1581897
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	RGD:70982\|RGD:3387	Rat	PMID:19318234\|RGD:10045585
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	RGD:620800	Rat	PMID:25436615\|RGD:11561967
Molecular Function	GO:0005515	protein binding	Vdac1	IPI	UniProtKB:Q07812	Rat	PMID:9843949\|RGD:8554139
Molecular Function	GO:0019901	protein kinase binding	VDAC1	IPI	UniProtKB:Q5S007	Human	PMID:21370995
Molecular Function	GO:0044877	protein-containing complex binding	Vdac1	IDA		Rat	PMID:9459579\|RGD:4891003
Molecular Function	GO:0044325	transmembrane transporter binding	VDAC1	IPI	UniProtKB:Q07817	Human	PMID:25296756
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	VDAC1	IDA		Human	PMID:8420959
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	Vdac1	IDA		Mouse	MGI:MGI:3850309\|PMID:18988731
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	Vdac1	IDA		Rat	PMID:12438411\|RGD:634413
Molecular Function	GO:0008308	voltage-gated monoatomic anion channel activity	Vdac1	IDA		Rat	PMID:15351738\|RGD:1581894
Cellular Component	GO:0070062	extracellular exosome	VDAC1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	VDAC1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	VDAC1	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	VDAC1	IDA		Human	PMID:27641616
Cellular Component	GO:0016020	membrane	Vdac1	IDA		Mouse	MGI:MGI:3850309\|PMID:18988731
Cellular Component	GO:0005743	mitochondrial inner membrane	Vdac1	HDA		Mouse	PMID:12865426
Cellular Component	GO:0031966	mitochondrial membrane	VDAC1	IDA		Human	PMID:31015432
Cellular Component	GO:0042645	mitochondrial nucleoid	VDAC1	IDA		Human	PMID:18063578
Cellular Component	GO:0005741	mitochondrial outer membrane	VDAC1	IDA		Human	PMID:17008324
Cellular Component	GO:0005741	mitochondrial outer membrane	VDAC1	IDA		Human	PMID:25244949
Cellular Component	GO:0005741	mitochondrial outer membrane	VDAC1	IDA		Human	PMID:7539795
Cellular Component	GO:0005741	mitochondrial outer membrane	Vdac1	IDA		Rat	PMID:12438411\|RGD:634413
Cellular Component	GO:0005741	mitochondrial outer membrane	Vdac1	IDA		Rat	PMID:15044178\|RGD:1581897
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	VDAC1	IDA		Human	PMID:26387735
Cellular Component	GO:0005739	mitochondrion	VDAC1	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	VDAC1	IDA		Human	PMID:30188326
Cellular Component	GO:0005739	mitochondrion	VDAC1	IDA		Human	PMID:31206022
Cellular Component	GO:0005739	mitochondrion	Vdac1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Vdac1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Mouse	PMID:19646951
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Mouse	PMID:23028046
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Mouse	PMID:17376863
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Rat	PMID:14759607\|RGD:10003048
Cellular Component	GO:0005739	mitochondrion	Vdac1	IDA		Rat	PMID:17893921\|RGD:10003051
Cellular Component	GO:0043209	myelin sheath	Vdac1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0005634	nucleus	VDAC1	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	VDAC1	IDA		Human	PMID:25296756
Cellular Component	GO:0098839	postsynaptic density membrane	Vdac1	IDA		Rat	PMID:10208569\|RGD:155230777
Cellular Component	GO:0048787	presynaptic active zone membrane	Vdac1	EXP		Rat	PMID:19187093\|RGD:10003050
Cellular Component	GO:0048787	presynaptic active zone membrane	Vdac1	IDA		Rat	PMID:19187093\|RGD:10003050
Cellular Component	GO:0032991	protein-containing complex	Vdac1	IDA		Rat	PMID:9459579\|RGD:4891003
Cellular Component	GO:0008021	synaptic vesicle	Vdac1	IDA		Rat	PMID:19187093\|RGD:10003050
Biological Process	GO:0006915	apoptotic process	VDAC1	IDA		Human	PMID:25296756
Biological Process	GO:0001662	behavioral fear response	Vdac1	IMP	MGI:MGI:2182154	Mouse	PMID:11907043
Biological Process	GO:0007268	chemical synaptic transmission	Vdac1	IMP	MGI:MGI:2182154	Mouse	PMID:11907043
Biological Process	GO:0030855	epithelial cell differentiation	VDAC1	IEP		Human	PMID:21492153
Biological Process	GO:0007612	learning	Vdac1	IMP	MGI:MGI:2182154	Mouse	PMID:11907043
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	Vdac1	IDA		Rat	PMID:12438411\|RGD:634413
Biological Process	GO:0006820	monoatomic anion transport	VDAC1	IDA		Human	PMID:8420959
Biological Process	GO:0043066	negative regulation of apoptotic process	VDAC1	IMP		Human	PMID:32047033
Biological Process	GO:0110099	negative regulation of calcium import into the mitochondrion	VDAC1	IMP		Human	PMID:32047033
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Vdac1	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454
Biological Process	GO:0007270	neuron-neuron synaptic transmission	Vdac1	IMP	MGI:MGI:2182154	Mouse	PMID:11907043
Biological Process	GO:1905091	positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	VDAC1	IMP		Human	PMID:32047033
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	Vdac1	IMP		Mouse	MGI:MGI:5689082\|PMID:25470454

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.