Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Vegfc

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes VEGFC
- Mouse genes Vegfc
- Rat genes Vegfc
- Zfish genes vegfc
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vegfc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042056	chemoattractant activity	VEGFC	IDA		Human	PMID:19275959
Molecular Function	GO:0005515	protein binding	VEGFC	IPI	UniProtKB:P35968	Human	PMID:20145116
Molecular Function	GO:0005515	protein binding	VEGFC	IPI	UniProtKB:P35916	Human	PMID:21130043
Molecular Function	GO:0005515	protein binding	VEGFC	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Vegfc	IPI	UniProtKB:O60462	Mouse	MGI:MGI:5918646\|PMID:25752543
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	VEGFC	IPI	UniProtKB:P35916	Human	PMID:23878260
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	Vegfc	IPI	UniProtKB:P35916	Mouse	PMID:9012504
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	Vegfc	IPI	PR:P35917	Mouse	PMID:9247316
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	Vegfc	IMP		Rat	PMID:11683876\|RGD:727326
Molecular Function	GO:0005172	vascular endothelial growth factor receptor binding	vegfc	IPI	UniProtKB:P35968	Zfish	PMID:14710191
Cellular Component	GO:0005615	extracellular space	Vegfc	HDA		Mouse	MGI:MGI:5640941\|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Vegfc	IDA		Mouse	MGI:MGI:5568630\|PMID:24552833
Cellular Component	GO:0005615	extracellular space	Vegfc	IDA		Mouse	PMID:9247316
Biological Process	GO:0001525	angiogenesis	Vegfc	IMP		Rat	PMID:12706123\|RGD:1580593
Biological Process	GO:0001525	angiogenesis	vegfc	IMP		Zfish	PMID:14710191
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-GENO-040827-1,ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:16617120
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-041014-73,ZFIN:ZDB-GENE-070810-6	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-111104-5	Zfish	PMID:22007135
Biological Process	GO:0001525	angiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2	Zfish	PMID:22007135
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-MRPHLNO-050513-12,ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:16617120
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-050407-1,ZFIN:ZDB-GENE-070810-6	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:16617120
Biological Process	GO:0001525	angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-050407-1	Zfish	PMID:28087639
Biological Process	GO:0009887	animal organ morphogenesis	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:14634646
Biological Process	GO:0001568	blood vessel development	vegfc	IGI	ZFIN:ZDB-GENO-130719-5	Zfish	PMID:23462469
Biological Process	GO:0001568	blood vessel development	vegfc	IMP	ZFIN:ZDB-GENO-130718-6	Zfish	PMID:23462469
Biological Process	GO:0048514	blood vessel morphogenesis	vegfc	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	vegfc	IGI	ZFIN:ZDB-GENO-130719-1,ZFIN:ZDB-MRPHLNO-070509-2	Zfish	PMID:23462469
Biological Process	GO:0061026	cardiac muscle tissue regeneration	vegfc	IMP	ZFIN:ZDB-GENO-220421-5	Zfish	PMID:31702554
Biological Process	GO:0008283	cell population proliferation	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:16462734
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Vegfc	IEP		Mouse	PMID:20439489
Biological Process	GO:0007492	endoderm development	vegfc	IMP		Zfish	PMID:14710191
Biological Process	GO:0014009	glial cell proliferation	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:16462734
Biological Process	GO:0050930	induction of positive chemotaxis	VEGFC	IDA		Human	PMID:19275959
Biological Process	GO:0001945	lymph vessel development	vegfc	IMP	ZFIN:ZDB-GENO-200730-28	Zfish	PMID:31452940
Biological Process	GO:0001945	lymph vessel development	vegfc	IGI	ZFIN:ZDB-GENE-070810-6	Zfish	PMID:31452940
Biological Process	GO:0001945	lymph vessel development	vegfc	IMP	ZFIN:ZDB-GENO-170421-20	Zfish	PMID:28087639
Biological Process	GO:0001945	lymph vessel development	vegfc	IGI	ZFIN:ZDB-GENE-070810-6	Zfish	PMID:28087639
Biological Process	GO:0001945	lymph vessel development	vegfc	IMP	ZFIN:ZDB-GENO-170131-10	Zfish	PMID:27621059
Biological Process	GO:0001945	lymph vessel development	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2	Zfish	PMID:24311379
Biological Process	GO:0001945	lymph vessel development	vegfc	IGI	ZFIN:ZDB-GENE-070521-8	Zfish	PMID:24311379
Biological Process	GO:0036303	lymph vessel morphogenesis	vegfc	IMP	ZFIN:ZDB-GENO-170131-10	Zfish	PMID:27621059
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-220421-5	Zfish	PMID:31702554
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-220408-7	Zfish	PMID:31702554
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-100707-6	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-140903-2	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IGI	ZFIN:ZDB-GENO-140903-2,ZFIN:ZDB-MRPHLNO-140903-1	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:19287381
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IGI	ZFIN:ZDB-MRPHLNO-050225-3,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:18300419
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IGI	ZFIN:ZDB-MRPHLNO-100707-5,ZFIN:ZDB-MRPHLNO-140903-1	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-141009-8	Zfish	PMID:24523457
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2	Zfish	PMID:28785085
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-140903-2	Zfish	PMID:24523457
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-100707-6	Zfish	PMID:20549745
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-100707-5	Zfish	PMID:20549745
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-100707-5	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-130718-6	Zfish	PMID:23462469
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-170131-10	Zfish	PMID:27621059
Biological Process	GO:0001946	lymphangiogenesis	vegfc	IMP		Zfish	PMID:16782017
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:14634646
Biological Process	GO:0008045	motor neuron axon guidance	vegfc	IMP	ZFIN:ZDB-MRPHLNO-100707-6	Zfish	PMID:24046321
Biological Process	GO:0045776	negative regulation of blood pressure	Vegfc	IMP		Rat	PMID:19412173\|RGD:2315485
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Vegfc	IDA		Mouse	MGI:MGI:6378108\|PMID:26934950
Biological Process	GO:0045766	positive regulation of angiogenesis	Vegfc	IDA		Mouse	MGI:MGI:5568630\|PMID:24552833
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	Vegfc	IMP		Rat	PMID:12706123\|RGD:1580593
Biological Process	GO:0030335	positive regulation of cell migration	Vegfc	IDA		Mouse	MGI:MGI:6378108\|PMID:26934950
Biological Process	GO:0008284	positive regulation of cell population proliferation	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:16462734
Biological Process	GO:0008284	positive regulation of cell population proliferation	Vegfc	IGI	MGI:MGI:95561	Mouse	PMID:9247316
Biological Process	GO:0008284	positive regulation of cell population proliferation	Vegfc	IDA		Rat	PMID:16462734\|RGD:8554518
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	vegfc	IMP	ZFIN:ZDB-GENO-130809-5	Zfish	PMID:23698350
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Vegfc	IMP		Rat	PMID:16618418\|RGD:1580592
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Vegfc	IMP	MGI:MGI:3026650	Mouse	PMID:16462734
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	Vegfc	IDA		Mouse	MGI:MGI:5568630\|PMID:24552833
Biological Process	GO:1901492	positive regulation of lymphangiogenesis	Vegfc	IDA		Mouse	PMID:20133819
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	VEGFC	IDA		Human	PMID:19275959
Biological Process	GO:1902462	positive regulation of mesenchymal stem cell proliferation	Vegfc	IDA		Mouse	MGI:MGI:6378108\|PMID:26934950
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Vegfc	IDA		Rat	PMID:16462734\|RGD:8554518
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	Vegfc	IMP		Rat	PMID:11683876\|RGD:727326
Biological Process	GO:0045860	positive regulation of protein kinase activity	Vegfc	IDA		Mouse	MGI:MGI:6378108\|PMID:26934950
Biological Process	GO:0050714	positive regulation of protein secretion	Vegfc	IMP		Rat	PMID:16618418\|RGD:1580592
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	Vegfc	IMP		Rat	PMID:11683876\|RGD:727326
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	vegfc	IGI	ZFIN:ZDB-GENO-150506-3,ZFIN:ZDB-MRPHLNO-051212-2	Zfish	PMID:25294789
Biological Process	GO:0009410	response to xenobiotic stimulus	Vegfc	IEP		Rat	PMID:19147132\|RGD:2315486
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IMP	ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-051212-3	Zfish	PMID:19287381
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IDA		Zfish	PMID:22340502
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-040303-4,ZFIN:ZDB-GENO-131118-14	Zfish	PMID:22340502
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-040303-4,ZFIN:ZDB-MRPHLNO-060515-1	Zfish	PMID:22340502
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENO-130718-6,ZFIN:ZDB-MRPHLNO-070509-2	Zfish	PMID:23462469
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENO-130719-5	Zfish	PMID:23462469
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IMP	ZFIN:ZDB-GENO-130718-6	Zfish	PMID:23462469
Biological Process	GO:0002040	sprouting angiogenesis	vegfc	IGI	ZFIN:ZDB-GENE-040303-4,ZFIN:ZDB-MRPHLNO-120302-10	Zfish	PMID:22340502
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	VEGFC	IDA		Human	PMID:23878260
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Vegfc	IDA		Mouse	MGI:MGI:5568630\|PMID:24552833
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Vegfc	IGI	MGI:MGI:95561	Mouse	PMID:9247316
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Vegfc	IDA		Mouse	PMID:9012504
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	vegfc	IGI	ZFIN:ZDB-MRPHLNO-051212-2,ZFIN:ZDB-MRPHLNO-111104-5	Zfish	PMID:22007135
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	vegfc	IGI	ZFIN:ZDB-GENE-090506-7,ZFIN:ZDB-GENO-140902-3	Zfish	PMID:25814692
Biological Process	GO:0048845	venous blood vessel morphogenesis	vegfc	IMP	ZFIN:ZDB-GENO-130809-5	Zfish	PMID:23698350
Biological Process	GO:0060855	venous endothelial cell migration involved in lymph vessel development	vegfc	IGI	ZFIN:ZDB-GENO-141013-2	Zfish	PMID:24523457
Biological Process	GO:0060855	venous endothelial cell migration involved in lymph vessel development	vegfc	IMP	ZFIN:ZDB-GENO-140902-3	Zfish	PMID:24523457

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.