Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VEGFD
  • Mouse genes Vegfd
  • Rat genes Vegfd
  • Zfish genes vegfd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vegfd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042056	chemoattractant activity	VEGFD	IDA		Human	PMID:19275959
Molecular Function	GO:0008083	growth factor activity	Vegfd	IDA		Mouse	PMID:8876195
Molecular Function	GO:0042802	identical protein binding	Vegfd	IPI	PR:P97946	Mouse	PMID:11279005
Molecular Function	GO:0005515	protein binding	VEGFD	IPI	UniProtKB:Q15836	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	Vegfd	IPI	PR:P35917	Mouse	PMID:11279005
Molecular Function	GO:0005515	protein binding	vegfd	IPI	ZFIN:ZDB-GENE-041001-112	Zfish	PMID:28087639
Molecular Function	GO:0043185	vascular endothelial growth factor receptor 3 binding	Vegfd	IDA		Mouse	PMID:11279005
Molecular Function	GO:0005172	vascular endothelial growth factor receptor binding	VEGFD	IPI	UniProtKB:P35916	Human	PMID:9435229
Molecular Function	GO:0005172	vascular endothelial growth factor receptor binding	Vegfd	IMP		Rat	PMID:11683876|RGD:727326
Cellular Component	GO:0005576	extracellular region	Vegfd	IDA		Mouse	PMID:8876195
Cellular Component	GO:0005615	extracellular space	Vegfd	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Vegfd	IDA		Mouse	PMID:11574540
Biological Process	GO:0001525	angiogenesis	vegfd	IGI	ZFIN:ZDB-GENE-050407-1	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfd	IGI	ZFIN:ZDB-GENE-041001-112	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfd	IGI	ZFIN:ZDB-GENE-040303-4,ZFIN:ZDB-GENE-041014-73	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfd	IGI	ZFIN:ZDB-GENE-040303-4,ZFIN:ZDB-GENE-050407-1	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfd	IGI	ZFIN:ZDB-GENE-041001-112,ZFIN:ZDB-GENE-050407-1	Zfish	PMID:28087639
Biological Process	GO:0001525	angiogenesis	vegfd	IMP		Zfish	PMID:28087639
Biological Process	GO:0008015	blood circulation	vegfd	IMP		Zfish	PMID:17466267
Biological Process	GO:0001568	blood vessel development	vegfd	IGI	ZFIN:ZDB-MRPHLNO-080725-1,ZFIN:ZDB-MRPHLNO-151020-4	Zfish	PMID:24269955
Biological Process	GO:0048514	blood vessel morphogenesis	vegfd	IMP		Zfish	PMID:17466267
Biological Process	GO:0071542	dopaminergic neuron differentiation	Vegfd	IDA		Mouse	MGI:MGI:5700491|PMID:22535492
Biological Process	GO:0048144	fibroblast proliferation	Vegfd	IDA		Mouse	PMID:8876195
Biological Process	GO:0050930	induction of positive chemotaxis	VEGFD	IDA		Human	PMID:19275959
Biological Process	GO:0001945	lymph vessel development	vegfd	IGI	ZFIN:ZDB-GENE-040303-4	Zfish	PMID:31452940
Biological Process	GO:0001945	lymph vessel development	vegfd	IMP	ZFIN:ZDB-GENO-200730-28	Zfish	PMID:31452940
Biological Process	GO:0001945	lymph vessel development	vegfd	IMP	ZFIN:ZDB-GENO-170421-7	Zfish	PMID:28087639
Biological Process	GO:0001945	lymph vessel development	vegfd	IGI	ZFIN:ZDB-GENE-980526-326	Zfish	PMID:28087639
Biological Process	GO:0001945	lymph vessel development	vegfd	IGI	ZFIN:ZDB-GENE-040303-4	Zfish	PMID:28087639
Biological Process	GO:0001946	lymphangiogenesis	vegfd	IGI	ZFIN:ZDB-GENO-140903-2,ZFIN:ZDB-MRPHLNO-140903-1	Zfish	PMID:24903752
Biological Process	GO:0001946	lymphangiogenesis	vegfd	IGI	ZFIN:ZDB-MRPHLNO-100707-5,ZFIN:ZDB-MRPHLNO-140903-1	Zfish	PMID:24903752
Biological Process	GO:0008284	positive regulation of cell population proliferation	Vegfd	IDA		Mouse	PMID:11606379
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Vegfd	IMP		Rat	PMID:17404025|RGD:2314331
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	VEGFD	IDA		Human	PMID:19275959
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	Vegfd	IMP		Rat	PMID:11683876|RGD:727326
Biological Process	GO:0009617	response to bacterium	Vegfd	IEP		Mouse	PMID:23012479
Biological Process	GO:0001666	response to hypoxia	Vegfd	IEP		Rat	PMID:17289933|RGD:1642045
Biological Process	GO:0070555	response to interleukin-1	Vegfd	IEP		Rat	PMID:17929249|RGD:2314330
Biological Process	GO:0007165	signal transduction	Vegfd	IDA		Mouse	MGI:MGI:83316|PMID:8876195
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Vegfd	IGI	UniProtKB:P35916	Mouse	PMID:11574540
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Vegfd	IMP		Rat	PMID:11683876|RGD:727326

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern