Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VGLL4
  • Mouse genes Vgll4
  • Rat genes Vgll4
  • Zfish genes vgll4a,vgll4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vgll4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VGLL4	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	VGLL4	IPI	UniProtKB:Q15561	Human	PMID:24525233
Molecular Function	GO:0005515	protein binding	VGLL4	IPI	UniProtKB:P15884	Human	PMID:28051067
Molecular Function	GO:0005515	protein binding	VGLL4	IPI	UniProtKB:Q15562-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VGLL4	IPI	UniProtKB:Q99594	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Vgll4	IPI	UniProtKB:P28347	Mouse	MGI:MGI:6392921|PMID:15140898
Molecular Function	GO:0005515	protein binding	Vgll4	IPI	UniProtKB:Q15561|UniProtKB:Q62296	Mouse	MGI:MGI:5616280|PMID:24525233
Molecular Function	GO:0005515	protein binding	Vgll4	IPI	UniProtKB:B2RWS6|UniProtKB:P30051	Mouse	MGI:MGI:6120600|PMID:27720608
Cellular Component	GO:0005634	nucleus	Vgll4	IDA		Mouse	MGI:MGI:6392921|PMID:15140898
Biological Process	GO:0060271	cilium assembly	vgll4b	IMP	ZFIN:ZDB-MRPHLNO-130729-12,ZFIN:ZDB-MRPHLNO-200323-3	Zfish	PMID:31513014
Biological Process	GO:0061371	determination of heart left/right asymmetry	vgll4b	IMP	ZFIN:ZDB-MRPHLNO-130729-12	Zfish	PMID:31513014
Biological Process	GO:0061371	determination of heart left/right asymmetry	vgll4b	IMP	ZFIN:ZDB-MRPHLNO-200323-3	Zfish	PMID:31513014
Biological Process	GO:0061371	determination of heart left/right asymmetry	vgll4b	IMP	ZFIN:ZDB-GENO-201216-9	Zfish	PMID:31513014
Biological Process	GO:0035329	hippo signaling	vgll4b	IMP		Zfish	PMID:24560909
Biological Process	GO:0070121	Kupffer's vesicle development	vgll4b	IMP	ZFIN:ZDB-MRPHLNO-130729-12,ZFIN:ZDB-MRPHLNO-200323-3	Zfish	PMID:31513014
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	Vgll4	IMP		Mouse	MGI:MGI:6120600|PMID:27720608
Biological Process	GO:0030308	negative regulation of cell growth	VGLL4	IDA		Human	PMID:28051067
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Vgll4	IDA		Mouse	MGI:MGI:6392921|PMID:15140898
Biological Process	GO:0035331	negative regulation of hippo signaling	VGLL4	IDA		Human	PMID:28051067
Biological Process	GO:0035331	negative regulation of hippo signaling	Vgll4	IDA		Mouse	MGI:MGI:6120600|PMID:27720608
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	VGLL4	IDA		Human	PMID:28051067
Biological Process	GO:0045732	positive regulation of protein catabolic process	Vgll4	IDA		Mouse	MGI:MGI:6120600|PMID:27720608

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern