Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VLDLR
  • Mouse genes Vldlr
  • Rat genes Vldlr
  • Zfish genes vldlr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vldlr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034185	apolipoprotein binding	VLDLR	IDA		Human	PMID:10571240
Molecular Function	GO:0048306	calcium-dependent protein binding	VLDLR	IPI	UniProtKB:Q60841	Human	PMID:10571240
Molecular Function	GO:0038024	cargo receptor activity	VLDLR	IDA		Human	PMID:10571240
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q60841	Human	PMID:10571240
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q60841	Human	PMID:10571241
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q99068	Human	PMID:10571241
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q61205	Human	PMID:17330141
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q61206	Human	PMID:17330141
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q60841	Human	PMID:17548821
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:P30533	Human	PMID:20223215
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:Q60841	Human	PMID:20223215
Molecular Function	GO:0005515	protein binding	VLDLR	IPI	UniProtKB:P30533	Human	PMID:8083232
Molecular Function	GO:0005515	protein binding	Vldlr	IPI	PR:P97318	Mouse	PMID:15249135
Molecular Function	GO:0038025	reelin receptor activity	Vldlr	IGI	UniProtKB:Q924X6	Mouse	MGI:MGI:3821675|PMID:18778775
Molecular Function	GO:0038025	reelin receptor activity	Vldlr	IMP		Mouse	MGI:MGI:3821675|PMID:18778775
Molecular Function	GO:0034189	very-low-density lipoprotein particle binding	VLDLR	IDA		Human	PMID:10571240
Molecular Function	GO:0030229	very-low-density lipoprotein particle receptor activity	VLDLR	IDA		Human	PMID:8083232
Cellular Component	GO:0045177	apical part of cell	Vldlr	IDA		Rat	PMID:19946030|RGD:2317766
Cellular Component	GO:0009986	cell surface	Vldlr	IDA		Rat	PMID:19233325|RGD:2324641
Cellular Component	GO:0005615	extracellular space	Vldlr	IDA		Mouse	MGI:MGI:3773783|PMID:15950758
Cellular Component	GO:0016020	membrane	VLDLR	IDA		Human	PMID:15082773
Cellular Component	GO:0005634	nucleus	Vldlr	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Vldlr	IDA		Rat	PMID:19233325|RGD:2324641
Cellular Component	GO:0043235	receptor complex	VLDLR	IDA		Human	PMID:23382219
Biological Process	GO:0042149	cellular response to glucose starvation	Vldlr	IEP		Rat	PMID:18262491|RGD:2324645
Biological Process	GO:0071456	cellular response to hypoxia	Vldlr	IDA		Rat	PMID:19233325|RGD:2324641
Biological Process	GO:0032869	cellular response to insulin stimulus	Vldlr	IEP		Rat	PMID:15878964|RGD:1625575
Biological Process	GO:0071347	cellular response to interleukin-1	Vldlr	IEP		Rat	PMID:16376325|RGD:1625574
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Vldlr	IEP		Rat	PMID:16376325|RGD:1625574
Biological Process	GO:0021987	cerebral cortex development	Vldlr	IEP		Rat	PMID:20368265|RGD:2324624
Biological Process	GO:0048813	dendrite morphogenesis	Vldlr	IMP		Mouse	MGI:MGI:3821675|PMID:18778775
Biological Process	GO:0034436	glycoprotein transport	VLDLR	IDA		Human	PMID:10571240
Biological Process	GO:0007507	heart development	Vldlr	IEP		Rat	PMID:12051760|RGD:625449
Biological Process	GO:1900006	positive regulation of dendrite development	Vldlr	IGI	UniProtKB:Q924X6	Mouse	MGI:MGI:3821675|PMID:18778775
Biological Process	GO:0045860	positive regulation of protein kinase activity	Vldlr	IGI	MGI:MGI:103022	Mouse	PMID:12526740
Biological Process	GO:0045860	positive regulation of protein kinase activity	Vldlr	IGI	MGI:MGI:1340044	Mouse	PMID:12526740
Biological Process	GO:0006898	receptor-mediated endocytosis	VLDLR	IDA		Human	PMID:10571240
Biological Process	GO:0038026	reelin-mediated signaling pathway	Vldlr	IGI	UniProtKB:Q924X6	Mouse	MGI:MGI:3821675|PMID:18778775
Biological Process	GO:0009725	response to hormone	Vldlr	IEP		Rat	PMID:7929362|RGD:1625580
Biological Process	GO:0001666	response to hypoxia	Vldlr	IEP		Rat	PMID:15942958|RGD:1598733
Biological Process	GO:0032496	response to lipopolysaccharide	Vldlr	IEP		Rat	PMID:16376325|RGD:1625574
Biological Process	GO:0007584	response to nutrient	Vldlr	IEP		Rat	PMID:11882325|RGD:1625576
Biological Process	GO:0009410	response to xenobiotic stimulus	Vldlr	IEP		Rat	PMID:19359144|RGD:2317787
Biological Process	GO:0021517	ventral spinal cord development	Vldlr	IEP		Mouse	MGI:MGI:4849611|PMID:20711475
Biological Process	GO:0034447	very-low-density lipoprotein particle clearance	VLDLR	IDA		Human	PMID:8083232

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern