Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS13C
  • Mouse genes Vps13c
  • Rat genes Vps13c
  • Zfish genes vps13c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps13c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005829	cytosol	VPS13C	IDA		Human	PMID:26942284
Cellular Component	GO:0032127	dense core granule membrane	Vps13c	IDA		Mouse	PMID:27329800
Cellular Component	GO:0005789	endoplasmic reticulum membrane	VPS13C	IDA		Human	PMID:30093493
Cellular Component	GO:0070062	extracellular exosome	VPS13C	HDA		Human	PMID:19056867
Cellular Component	GO:0005770	late endosome	VPS13C	IDA		Human	PMID:30093493
Cellular Component	GO:0005811	lipid droplet	VPS13C	IDA		Human	PMID:30093493
Cellular Component	GO:0005764	lysosome	VPS13C	IDA		Human	PMID:30093493
Cellular Component	GO:0005741	mitochondrial outer membrane	VPS13C	IDA		Human	PMID:26942284
Biological Process	GO:0007005	mitochondrion organization	VPS13C	IMP		Human	PMID:26942284
Biological Process	GO:1905090	negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	VPS13C	IMP		Human	PMID:26942284
Biological Process	GO:0032868	response to insulin	Vps13c	IMP	MGI:MGI:4410453,MGI:MGI:5907128	Mouse	PMID:27329800

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern