Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS28
  • Mouse genes Vps28
  • Rat genes Vps28
  • Zfish genes vps28
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps28

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q61187	Human	PMID:11134028
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:15218037
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H9H4	Human	PMID:15218037
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:P12757	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q16637	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8N1B4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H9H4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:P12757	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:P14373	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q08379	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q16637	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q16637-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8IYX7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8N1B4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8N6Y0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q8WWW0-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99081-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H257-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H257-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H2G9	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H9H4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9NS73-5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q99816	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H9H4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:Q9H9H4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	VPS28	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Vps28	IPI	UniProtKB:O54788	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0005515	protein binding	Vps28	IPI	UniProtKB:Q99683	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0005515	protein binding	Vps28	IPI	UniProtKB:O35099	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0043130	ubiquitin binding	VPS28	IDA		Human	PMID:11916981
Cellular Component	GO:0005737	cytoplasm	VPS28	IDA		Human	PMID:18077552
Cellular Component	GO:0005829	cytosol	VPS28	IDA		Human	PMID:11134028
Cellular Component	GO:0005829	cytosol	Vps28	IDA		Rat	PMID:11134028|RGD:10047383
Cellular Component	GO:0005769	early endosome	VPS28	IDA		Human	PMID:11916981
Cellular Component	GO:0005768	endosome	VPS28	IDA		Human	PMID:11134028
Cellular Component	GO:0005768	endosome	VPS28	IDA		Human	PMID:17940959
Cellular Component	GO:0010008	endosome membrane	VPS28	IDA		Human	PMID:11134028
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IPI		Human	PMID:18005716
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IPI		Human	PMID:21757351
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IPI		Human	PMID:32424346
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IDA		Human	PMID:18005716
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IDA		Human	PMID:20654576
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IDA		Human	PMID:21757351
Cellular Component	GO:0000813	ESCRT I complex	VPS28	IDA		Human	PMID:22232651
Cellular Component	GO:0070062	extracellular exosome	VPS28	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	VPS28	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	VPS28	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	VPS28	HDA		Human	PMID:23533145
Cellular Component	GO:0005886	plasma membrane	VPS28	IDA		Human	PMID:17940959
Biological Process	GO:0031397	negative regulation of protein ubiquitination	VPS28	IDA		Human	PMID:18077552
Biological Process	GO:0045732	positive regulation of protein catabolic process	VPS28	IMP		Human	PMID:11916981
Biological Process	GO:2000397	positive regulation of ubiquitin-dependent endocytosis	VPS28	IMP		Human	PMID:11916981
Biological Process	GO:0060041	retina development in camera-type eye	vps28	IMP	ZFIN:ZDB-GENO-200122-5	Zfish	PMID:30624971
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	VPS28	IMP		Human	PMID:21757351

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern