Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS33A
  • Mouse genes Vps33a
  • Rat genes Vps33a
  • Zfish genes vps33a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps33a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H9C1	Human	PMID:19109425
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:20190753
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9P2Y5	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:23901104
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:P56962	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9P253	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9P2Y5	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:25783203
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9P253	Human	PMID:25783203
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H270	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9P253	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:P56962|UniProtKB:Q9H269	Human	PMID:28013294
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9Y4G2	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:29778605
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H270	Human	PMID:29778605
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9HAT0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:P01011	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q13561	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q14790	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VPS33A	IPI	UniProtKB:Q9H269	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Vps33a	IPI	UniProtKB:Q9H270	Rat	PMID:11382755|RGD:2312431
Molecular Function	GO:0005515	protein binding	Vps33a	IPI	UniProtKB:Q9P253	Rat	PMID:11382755|RGD:2312431
Molecular Function	GO:0044877	protein-containing complex binding	Vps33a	IPI	RGD:1317575|RGD:1323077	Rat	PMID:11382755|RGD:2312431
Cellular Component	GO:0005776	autophagosome	Vps33a	IDA		Mouse	MGI:MGI:5805578|PMID:27628032
Cellular Component	GO:0033263	CORVET complex	Vps33a	IDA		Mouse	MGI:MGI:5645189|PMID:25266290
Cellular Component	GO:0031410	cytoplasmic vesicle	Vps33a	IDA		Rat	PMID:11382755|RGD:2312431
Cellular Component	GO:0005769	early endosome	VPS33A	IDA		Human	PMID:19109425
Cellular Component	GO:0030897	HOPS complex	VPS33A	IDA		Human	PMID:19109425
Cellular Component	GO:0030897	HOPS complex	VPS33A	IDA		Human	PMID:23901104
Cellular Component	GO:0030897	HOPS complex	VPS33A	IDA		Human	PMID:25783203
Cellular Component	GO:0005770	late endosome	VPS33A	IDA		Human	PMID:19109425
Cellular Component	GO:0005765	lysosomal membrane	VPS33A	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	Vps33a	IDA		Mouse	MGI:MGI:5805578|PMID:27628032
Cellular Component	GO:0048471	perinuclear region of cytoplasm	VPS33A	IDA		Human	PMID:19109425
Biological Process	GO:0097352	autophagosome maturation	VPS33A	IMP		Human	PMID:24554770
Biological Process	GO:0097352	autophagosome maturation	VPS33A	IMP		Human	PMID:25783203
Biological Process	GO:0008333	endosome to lysosome transport	VPS33A	IMP		Human	PMID:25783203
Biological Process	GO:0032418	lysosome localization	VPS33A	IDA		Human	PMID:15790593
Biological Process	GO:0032400	melanosome localization	VPS33A	IDA		Human	PMID:15790593
Biological Process	GO:0043473	pigmentation	Vps33a	IMP	MGI:MGI:1856687	Mouse	PMID:4777306
Biological Process	GO:0030220	platelet formation	Vps33a	IMP	MGI:MGI:1856687	Mouse	PMID:12538872
Biological Process	GO:0048070	regulation of developmental pigmentation	Vps33a	IMP	MGI:MGI:1856687	Mouse	PMID:12538872
Biological Process	GO:0035751	regulation of lysosomal lumen pH	VPS33A	IMP		Human	PMID:28013294
Biological Process	GO:0016192	vesicle-mediated transport	VPS33A	IDA		Human	PMID:15790593

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern