Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS39
  • Mouse genes Vps39
  • Rat genes Vps39
  • Zfish genes vps39
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps39

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P56962	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:Q9Y4G2	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P56962	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:32838362
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P56962	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:Q9P253	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:Q9Y4G2	Human	PMID:33452816
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:33845483
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:33947832
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P51149	Human	PMID:33947832
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	VPS39	IPI	UniProtKB:P0DTC3	Human	PMID:34706264
Molecular Function	GO:0005515	protein binding	Vps39	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Vps39	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Cellular Component	GO:0030123	AP-3 adaptor complex	Vps39	IDA		Mouse	MGI:MGI:5645203|PMID:21411634
Cellular Component	GO:0030897	HOPS complex	VPS39	IDA		Human	PMID:19109425
Cellular Component	GO:0030897	HOPS complex	VPS39	IDA		Human	PMID:23901104
Cellular Component	GO:0005770	late endosome	VPS39	IDA		Human	PMID:33422265
Cellular Component	GO:0031902	late endosome membrane	VPS39	IDA		Human	PMID:23167963
Cellular Component	GO:1902501	lysosomal HOPS complex	VPS39	IDA		Human	PMID:33422265
Cellular Component	GO:0005765	lysosomal membrane	VPS39	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	VPS39	IDA		Human	PMID:23167963
Biological Process	GO:0061909	autophagosome-lysosome fusion	VPS39	IDA		Human	PMID:33422265
Biological Process	GO:0006914	autophagy	VPS39	IMP		Human	PMID:24554770
Biological Process	GO:0048066	developmental pigmentation	vps39	IMP	ZFIN:ZDB-MRPHLNO-080728-1	Zfish	PMID:18077594
Biological Process	GO:0048066	developmental pigmentation	vps39	IMP	ZFIN:ZDB-GENO-080728-2	Zfish	PMID:18077594
Biological Process	GO:0032456	endocytic recycling	VPS39	IMP		Human	PMID:25266290
Biological Process	GO:0034058	endosomal vesicle fusion	VPS39	IDA		Human	PMID:23167963
Biological Process	GO:0008333	endosome to lysosome transport	VPS39	IMP		Human	PMID:25266290
Biological Process	GO:0008333	endosome to lysosome transport	VPS39	IMP		Human	PMID:25783203
Biological Process	GO:0001654	eye development	vps39	IMP	ZFIN:ZDB-GENO-080728-2	Zfish	PMID:18077594
Biological Process	GO:0001654	eye development	vps39	IMP	ZFIN:ZDB-MRPHLNO-080728-1	Zfish	PMID:18077594
Biological Process	GO:1902774	late endosome to lysosome transport	VPS39	IDA		Human	PMID:23167963
Biological Process	GO:0016192	vesicle-mediated transport	vps39	IMP	ZFIN:ZDB-GENO-080728-2	Zfish	PMID:18077594

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern