Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS41
  • Mouse genes Vps41
  • Rat genes Vps41
  • Zfish genes vps41
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	VPS41	IPI	UniProtKB:P49754	Human	PMID:24210660
Molecular Function	GO:0008017	microtubule binding	Vps41	IDA		Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9H9C1	Human	PMID:19109425
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9NVJ2	Human	PMID:21802320
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9P253	Human	PMID:23901104
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9H267	Human	PMID:23918659
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:P56962	Human	PMID:24554770
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q96NA2	Human	PMID:25445562
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9H270	Human	PMID:25500191
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9Y4G2	Human	PMID:25500191
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9P253	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9Y4G2	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:P0DTC3	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:P56962	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9H270	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9P253	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:Q9Y4G2	Human	PMID:33452816
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:P0DTC3	Human	PMID:33845483
Molecular Function	GO:0005515	protein binding	VPS41	IPI	UniProtKB:P0DTC3	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	Vps41	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Vps41	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0005515	protein binding	Vps41	IPI	UniProtKB:B5DFK6	Rat	PMID:24210660|RGD:10054072
Molecular Function	GO:0043621	protein self-association	Vps41	IDA		Rat	PMID:24210660|RGD:10054072
Cellular Component	GO:0030136	clathrin-coated vesicle	VPS41	IDA		Human	PMID:21411634
Cellular Component	GO:0005769	early endosome	Vps41	IDA		Mouse	PMID:14668490
Cellular Component	GO:0010008	endosome membrane	VPS41	IDA		Human	PMID:21411634
Cellular Component	GO:0005798	Golgi-associated vesicle	Vps41	IDA		Rat	PMID:24210660|RGD:10054072
Cellular Component	GO:0030897	HOPS complex	VPS41	IDA		Human	PMID:19109425
Cellular Component	GO:0030897	HOPS complex	VPS41	IDA		Human	PMID:23901104
Cellular Component	GO:0030897	HOPS complex	VPS41	IMP		Human	PMID:33851776
Cellular Component	GO:0005770	late endosome	VPS41	IDA		Human	PMID:33422265
Cellular Component	GO:0005770	late endosome	Vps41	IDA		Mouse	PMID:14668490
Cellular Component	GO:0031902	late endosome membrane	VPS41	IDA		Human	PMID:23167963
Cellular Component	GO:1902501	lysosomal HOPS complex	VPS41	IDA		Human	PMID:21802320
Cellular Component	GO:0005765	lysosomal membrane	VPS41	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	VPS41	IDA		Human	PMID:23167963
Cellular Component	GO:0005764	lysosome	VPS41	IDA		Human	PMID:21802320
Cellular Component	GO:0015630	microtubule cytoskeleton	Vps41	IDA		Mouse	PMID:14668490
Biological Process	GO:0034058	endosomal vesicle fusion	VPS41	IMP		Human	PMID:23167963
Biological Process	GO:0008333	endosome to lysosome transport	VPS41	IMP		Human	PMID:25783203
Biological Process	GO:0008333	endosome to lysosome transport	vps41	IMP		Zfish	PMID:33764426|ZFIN:ZDB-PUB-210326-10
Biological Process	GO:1902774	late endosome to lysosome transport	VPS41	IMP		Human	PMID:23167963
Biological Process	GO:0045055	regulated exocytosis	Vps41	IMP		Rat	PMID:24210660|RGD:10054072
Biological Process	GO:0016192	vesicle-mediated transport	VPS41	IMP		Human	PMID:33851776
Biological Process	GO:0016192	vesicle-mediated transport	vps41	IMP	ZFIN:ZDB-CRISPR-220105-1	Zfish	PMID:33764426

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern