Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS53
  • Mouse genes Vps53
  • Rat genes Vps53
  • Zfish genes vps53
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps53

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS53	IPI	UniProtKB:Q8N1B4	Human	PMID:15878329
Molecular Function	GO:0005515	protein binding	VPS53	IPI	UniProtKB:Q9UID3	Human	PMID:20685960
Molecular Function	GO:0005515	protein binding	VPS53	IPI	UniProtKB:Q96JG6	Human	PMID:25799061
Molecular Function	GO:0005515	protein binding	VPS53	IPI	UniProtKB:Q96JG6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VPS53	IPI	UniProtKB:Q96JG6	Human	PMID:3172165
Molecular Function	GO:0005515	protein binding	Vps53	IPI	UniProtKB:Q5PPK9	Rat	PMID:27191843|RGD:11344934
Cellular Component	GO:0005829	cytosol	VPS53	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990745	EARP complex	VPS53	IPI		Human	PMID:25799061
Cellular Component	GO:1990745	EARP complex	VPS53	IDA		Human	PMID:25799061
Cellular Component	GO:0000938	GARP complex	VPS53	IDA		Human	PMID:19620288
Cellular Component	GO:0000938	GARP complex	VPS53	IDA		Human	PMID:25799061
Cellular Component	GO:0005794	Golgi apparatus	VPS53	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	VPS53	IDA		Human	PMID:15878329
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	VPS53	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	VPS53	IDA		Human	PMID:25799061
Cellular Component	GO:0048471	perinuclear region of cytoplasm	VPS53	IDA		Human	PMID:15878329
Cellular Component	GO:0055037	recycling endosome	VPS53	IDA		Human	PMID:25799061
Biological Process	GO:0032456	endocytic recycling	VPS53	IMP		Human	PMID:25799061
Biological Process	GO:0007041	lysosomal transport	VPS53	IMP		Human	PMID:25799061
Biological Process	GO:0006622	protein targeting to lysosome	Vps53	IMP		Mouse	PMID:28658628
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	VPS53	IMP		Human	PMID:25799061
Biological Process	GO:0090119	vesicle-mediated cholesterol transport	Vps53	IMP		Mouse	PMID:28658628

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern