Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VRTN
  • Mouse genes Vrtn
  • Rat genes Vrtn
  • Zfish genes vrtn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vrtn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	vrtn	IDA		Zfish	PMID:28928283
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:O95716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:P20336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:P20337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:P38919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:Q8WUD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:Q96E17	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:Q96LT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VRTN	IPI	UniProtKB:Q9BUI4	Human	PMID:32296183
Cellular Component	GO:0000785	chromatin	vrtn	IDA		Zfish	PMID:28928283
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	vrtn	IDA		Zfish	PMID:28928283

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern