Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VSIG4
  • Mouse genes Vsig4
  • Rat genes Vsig4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vsig4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001851	complement component C3b binding	VSIG4	IPI	UniProtKB:P01024	Human	PMID:17051150
Molecular Function	GO:0005515	protein binding	VSIG4	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIG4	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VSIG4	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Cellular Component	GO:0032991	protein-containing complex	VSIG4	IPI	UniProtKB:P01024	Human	PMID:17051150
Biological Process	GO:0045957	negative regulation of complement activation, alternative pathway	VSIG4	IPI	UniProtKB:P01024	Human	PMID:17051150
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Vsig4	IDA		Mouse	PMID:17016562
Biological Process	GO:0042130	negative regulation of T cell proliferation	Vsig4	IDA		Mouse	PMID:17016562
Biological Process	GO:0010628	positive regulation of gene expression	Vsig4	HMP		Rat	PMID:33633725|RGD:151665761

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern