Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VSX1
  • Mouse genes Vsx1
  • Rat genes Vsx1
  • Zfish genes vsx1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vsx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	vsx1	IDA		Zfish	PMID:25150888
Molecular Function	GO:0005515	protein binding	VSX1	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	VSX1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	vsx1	IDA		Zfish	PMID:24296303
Cellular Component	GO:0005634	nucleus	Vsx1	IDA		Mouse	PMID:11731243
Biological Process	GO:0048318	axial mesoderm development	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:24296303
Biological Process	GO:0030900	forebrain development	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:25150888
Biological Process	GO:0048329	negative regulation of axial mesodermal cell fate specification	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:24296303
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	vsx1	IDA		Zfish	PMID:24296303
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	vsx1	IDA		Zfish	PMID:25150888
Biological Process	GO:0048666	neuron development	Vsx1	IMP	MGI:MGI:3033929	Mouse	PMID:14745032
Biological Process	GO:0048666	neuron development	Vsx1	IMP	MGI:MGI:3040317	Mouse	PMID:15043821
Biological Process	GO:0042551	neuron maturation	Vsx1	IGI	MGI:MGI:1859086	Mouse	PMID:18322081
Biological Process	GO:0048339	paraxial mesoderm development	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:24296303
Biological Process	GO:0048348	paraxial mesodermal cell fate specification	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:24296303
Biological Process	GO:0021501	prechordal plate formation	vsx1	IMP	ZFIN:ZDB-MRPHLNO-140307-1	Zfish	PMID:25150888
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Vsx1	IMP	MGI:MGI:3033929	Mouse	PMID:14745032
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Vsx1	IMP	MGI:MGI:3040317	Mouse	PMID:15043821
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Vsx1	IGI	MGI:MGI:1859086	Mouse	PMID:18322081
Biological Process	GO:0007601	visual perception	Vsx1	IMP	MGI:MGI:3040317	Mouse	PMID:15043821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern