Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VSX2
  • Mouse genes Vsx2
  • Rat genes Vsx2
  • Zfish genes vsx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vsx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	VSX2	IDA		Human	PMID:15647262
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P02766	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P26378-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P29474	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P35240-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q00403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q5T3J3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q96BH6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q9NX09	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	VSX2	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Vsx2	IPI	UniProtKB:P13405|UniProtKB:Q08999	Mouse	MGI:MGI:1195383|PMID:9464541
Molecular Function	GO:0005515	protein binding	Vsx2	IPI	PR:Q6P5F9	Mouse	PMID:15767664
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	VSX2	IDA		Human	PMID:15647262
Molecular Function	GO:0043565	sequence-specific DNA binding	vsx2	IDA		Zfish	PMID:19344499
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	VSX2	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Vsx2	IDA		Mouse	PMID:15767664
Cellular Component	GO:0005737	cytoplasm	Vsx2	IDA		Mouse	PMID:19389377
Cellular Component	GO:0005622	intracellular anatomical structure	Vsx2	IDA		Mouse	PMID:10482234
Cellular Component	GO:0005634	nucleus	Vsx2	IDA		Mouse	PMID:19389377
Cellular Component	GO:0005634	nucleus	Vsx2	IDA		Mouse	PMID:15767664
Biological Process	GO:0043010	camera-type eye development	Vsx2	IGI	MGI:MGI:104554	Mouse	PMID:15576400
Biological Process	GO:0045165	cell fate commitment	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:15576400
Biological Process	GO:0008283	cell population proliferation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:8630490
Biological Process	GO:0008283	cell population proliferation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:16384989
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:16384989
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	VSX2	IDA		Human	PMID:15647262
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	vsx2	IDA		Zfish	PMID:19344499
Biological Process	GO:0007405	neuroblast proliferation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:16384989
Biological Process	GO:0008284	positive regulation of cell population proliferation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:8630490
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Vsx2	IDA		Mouse	PMID:15767664
Biological Process	GO:0061074	regulation of neural retina development	vsx2	IMP	ZFIN:ZDB-MRPHLNO-100503-2	Zfish	PMID:25872183
Biological Process	GO:0061074	regulation of neural retina development	vsx2	IGI	ZFIN:ZDB-GENE-020117-1,ZFIN:ZDB-GENE-050417-97	Zfish	PMID:25872183
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:16854970
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:8630490
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Vsx2	IMP	MGI:MGI:1856112	Mouse	PMID:8630490

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern