Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VTN
  • Mouse genes Vtn
  • Rat genes Vtn
  • Zfish genes vtna,vtnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vtn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Vtn	IDA		Rat	PMID:10988248|RGD:10003090
Molecular Function	GO:0050840	extracellular matrix binding	Vtn	IDA		Mouse	PMID:18757743
Molecular Function	GO:0008201	heparin binding	Vtn	IDA		Rat	PMID:8804356|RGD:10040982
Molecular Function	GO:0042802	identical protein binding	Vtn	IDA		Rat	PMID:17369286|RGD:10003099
Molecular Function	GO:0005178	integrin binding	VTN	IDA		Human	PMID:22505472
Molecular Function	GO:0005178	integrin binding	VTN	IPI	UniProtKB:P05106	Human	PMID:8837777
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P0C045	Human	PMID:16237761
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q4KTX9	Human	PMID:24664511
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q9HD26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:A0A024A2C9	Human	PMID:26538390
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:A4NBN9	Human	PMID:26538390
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75167	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75358	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75390	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75391	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75392	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P75611	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P78007	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P78031	Human	PMID:27616280
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q07021	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P69193	Human	PMID:29567995
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q9HD26	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:P05121	Human	PMID:31682300
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q15700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q92796	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q9HD26-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q9NSN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	VTN	IPI	UniProtKB:Q07021	Human	PMID:8900153
Cellular Component	GO:0005604	basement membrane	Vtn	IDA		Rat	PMID:11728964|RGD:10003096
Cellular Component	GO:0072562	blood microparticle	VTN	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	IDA		Human	PMID:1632457
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VTN	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Vtn	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Vtn	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Vtn	IDA		Rat	PMID:2426279|RGD:10003088
Cellular Component	GO:0005737	cytoplasm	Vtn	IDA		Rat	PMID:8837997|RGD:10003085
Cellular Component	GO:0005783	endoplasmic reticulum	VTN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	VTN	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	VTN	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Vtn	IDA		Mouse	PMID:15728191
Cellular Component	GO:0005576	extracellular region	VTN	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	VTN	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	VTN	IDA		Human	PMID:1695900
Cellular Component	GO:0005615	extracellular space	VTN	IDA		Human	PMID:29567995
Cellular Component	GO:0005615	extracellular space	Vtn	IDA		Rat	PMID:17567740|RGD:10003084
Cellular Component	GO:0005796	Golgi lumen	Vtn	IDA		Rat	PMID:10192552|RGD:10003091
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	VTN	IDA		Human	GO_REF:0000052
Cellular Component	GO:1904090	peptidase inhibitor complex	VTN	IPI		Human	PMID:12808446
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	VTN	IPI		Human	PMID:24465541
Cellular Component	GO:0048237	rough endoplasmic reticulum lumen	Vtn	IDA		Rat	PMID:10192552|RGD:10003091
Biological Process	GO:0033627	cell adhesion mediated by integrin	VTN	IDA		Human	PMID:8837777
Biological Process	GO:0016477	cell migration	VTN	IGI	ComplexPortal:CPX-1795	Human	PMID:22505472
Biological Process	GO:0007160	cell-matrix adhesion	VTN	IDA		Human	PMID:10022831
Biological Process	GO:0007160	cell-matrix adhesion	VTN	IGI	ComplexPortal:CPX-1795	Human	PMID:22505472
Biological Process	GO:0007160	cell-matrix adhesion	Vtn	IDA		Mouse	PMID:15728191
Biological Process	GO:0035987	endodermal cell differentiation	VTN	IDA		Human	PMID:23154389
Biological Process	GO:0030198	extracellular matrix organization	Vtn	IDA		Mouse	PMID:18757743
Biological Process	GO:0097421	liver regeneration	Vtn	IDA		Rat	PMID:10988248|RGD:10003090
Biological Process	GO:0010951	negative regulation of endopeptidase activity	VTN	IDA		Human	PMID:1695900
Biological Process	GO:0048709	oligodendrocyte differentiation	Vtn	IDA		Mouse	MGI:MGI:5619735|PMID:23155445
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Vtn	IDA		Mouse	PMID:18757743
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	VTN	IDA		Human	PMID:10022831
Biological Process	GO:0032092	positive regulation of protein binding	VTN	IDA		Human	PMID:1695900
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	VTN	IDA		Human	PMID:8626514
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	VTN	IDA		Human	PMID:8837777
Biological Process	GO:0051258	protein polymerization	Vtn	IDA		Rat	PMID:17369286|RGD:10003099
Biological Process	GO:0030155	regulation of cell adhesion	VTN	IDA		Human	PMID:10722842
Biological Process	GO:0061302	smooth muscle cell-matrix adhesion	VTN	IDA		Human	PMID:8837777

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern