Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VWA1
  • Mouse genes Vwa1
  • Rat genes Vwa1
  • Zfish genes vwa1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vwa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Vwa1	IDA		Mouse	PMID:16407285
Molecular Function	GO:0005515	protein binding	Vwa1	IPI	PR:Q05793	Mouse	PMID:16407285
Cellular Component	GO:0005604	basement membrane	Vwa1	IDA		Mouse	PMID:18314316
Cellular Component	GO:0005604	basement membrane	Vwa1	IDA		Mouse	PMID:18757743
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VWA1	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VWA1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	VWA1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Vwa1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Vwa1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	VWA1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	VWA1	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Vwa1	IDA		Mouse	PMID:16407285
Cellular Component	GO:0031012	extracellular matrix	Vwa1	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005576	extracellular region	Vwa1	IDA		Mouse	PMID:12062410
Cellular Component	GO:0005615	extracellular space	VWA1	HDA		Human	PMID:16502470
Cellular Component	GO:0005614	interstitial matrix	Vwa1	IDA		Mouse	PMID:18757743
Biological Process	GO:0007409	axonogenesis	vwa1	IMP	ZFIN:ZDB-CRISPR-211116-1,ZFIN:ZDB-CRISPR-211116-2	Zfish	PMID:33559681
Biological Process	GO:0007409	axonogenesis	vwa1	IMP	ZFIN:ZDB-MRPHLNO-211116-1	Zfish	PMID:33559681
Biological Process	GO:0048266	behavioral response to pain	Vwa1	IMP	MGI:MGI:3809230	Mouse	PMID:19279005
Biological Process	GO:0030198	extracellular matrix organization	Vwa1	IDA		Mouse	PMID:18757743
Biological Process	GO:0030198	extracellular matrix organization	Vwa1	IMP	MGI:MGI:3809230	Mouse	PMID:19279005
Biological Process	GO:0014032	neural crest cell development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-2	Zfish	PMID:33015062
Biological Process	GO:0014032	neural crest cell development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-1	Zfish	PMID:33015062
Biological Process	GO:0014032	neural crest cell development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-4	Zfish	PMID:33015062
Biological Process	GO:0014032	neural crest cell development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-3	Zfish	PMID:33015062
Biological Process	GO:0014032	neural crest cell development	vwa1	IMP	ZFIN:ZDB-MRPHLNO-210503-3	Zfish	PMID:33015062
Biological Process	GO:0061035	regulation of cartilage development	vwa1	IMP	ZFIN:ZDB-MRPHLNO-210503-3	Zfish	PMID:33015062
Biological Process	GO:0061035	regulation of cartilage development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-3	Zfish	PMID:33015062
Biological Process	GO:0061035	regulation of cartilage development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-2	Zfish	PMID:33015062
Biological Process	GO:0061035	regulation of cartilage development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-1	Zfish	PMID:33015062
Biological Process	GO:0061035	regulation of cartilage development	vwa1	IMP	ZFIN:ZDB-CRISPR-210503-4	Zfish	PMID:33015062
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	vwa1	IMP	ZFIN:ZDB-CRISPR-211116-1,ZFIN:ZDB-CRISPR-211116-2	Zfish	PMID:33559681
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	vwa1	IMP	ZFIN:ZDB-MRPHLNO-211116-1	Zfish	PMID:33559681

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern