Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WAC
  • Mouse genes Wac
  • Rat genes Wac
  • Zfish genes waca,wacb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wac

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	WAC	IDA		Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:P19012	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:O75150	Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:P49459	Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q5VTR2	Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q16236	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q6P597	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q8TDW5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q8WWB3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q99996-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WAC	IPI	UniProtKB:Q9Y228	Human	PMID:25416956
Molecular Function	GO:0000993	RNA polymerase II complex binding	WAC	IDA		Human	PMID:21329877
Cellular Component	GO:0005654	nucleoplasm	WAC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005681	spliceosomal complex	Wac	IDA		Mouse	PMID:11827461
Biological Process	GO:0006974	DNA damage response	WAC	IMP		Human	PMID:21329877
Biological Process	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	WAC	IMP		Human	PMID:21329877
Biological Process	GO:0010390	histone monoubiquitination	WAC	IMP		Human	PMID:21329877
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	WAC	IMP		Human	PMID:21329877
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	WAC	IMP		Human	PMID:22354037
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	WAC	IMP		Human	PMID:21329877
Biological Process	GO:0016239	positive regulation of macroautophagy	WAC	IMP		Human	PMID:22354037

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern