Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WASF2
  • Mouse genes Wasf2
  • Rat genes Wasf2
  • Zfish genes wasf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wasf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	WASF2	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:Q9UQB8-4	Human	PMID:11130076
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:P55160	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:O60504-2	Human	PMID:16483316
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:Q8WUW1	Human	PMID:18560548
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:Q8IUH5	Human	PMID:24705354
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:P55160	Human	PMID:32647003
Molecular Function	GO:0005515	protein binding	WASF2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Wasf2	IPI	UniProtKB:Q8CBW3	Mouse	MGI:MGI:4835598|PMID:20697350
Molecular Function	GO:0005515	protein binding	Wasf2	IPI	UniProtKB:Q8CBW3	Mouse	MGI:MGI:3771761|PMID:18044991
Molecular Function	GO:0005515	protein binding	Wasf2	IPI	UniProtKB:Q3URD3-4|UniProtKB:Q8CG48|UniProtKB:Q8CHG3	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0051018	protein kinase A binding	WASF2	IPI	UniProtKB:P13861	Human	PMID:25097019
Molecular Function	GO:0017124	SH3 domain binding	WASF2	IPI	UniProtKB:Q5T0N5	Human	PMID:19798448
Cellular Component	GO:0005911	cell-cell junction	Wasf2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0005769	early endosome	Wasf2	IDA		Mouse	PMID:12446704
Cellular Component	GO:0070062	extracellular exosome	WASF2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	WASF2	HDA		Human	PMID:23533145
Cellular Component	GO:0030027	lamellipodium	WASF2	IDA		Human	PMID:17101133
Cellular Component	GO:0030027	lamellipodium	Wasf2	IDA		Mouse	PMID:17664349
Cellular Component	GO:0032991	protein-containing complex	WASF2	IDA		Human	PMID:25097019
Cellular Component	GO:0001726	ruffle	Wasf2	IDA		Mouse	PMID:12446704
Cellular Component	GO:0031209	SCAR complex	WASF2	IDA		Human	PMID:17101133
Cellular Component	GO:0031209	SCAR complex	WASF2	IDA		Human	PMID:18560548
Cellular Component	GO:0031209	SCAR complex	WASF2	IMP		Human	PMID:21107423
Cellular Component	GO:0031209	SCAR complex	WASF2	IDA		Human	PMID:26428302
Cellular Component	GO:0031209	SCAR complex	Wasf2	IDA		Mouse	MGI:MGI:6508508|PMID:26428302
Cellular Component	GO:0045202	synapse	Wasf2	EXP		Mouse	PMID:28252024
Cellular Component	GO:0045202	synapse	Wasf2	IDA		Mouse	PMID:28252024
Biological Process	GO:0030036	actin cytoskeleton organization	Wasf2	IMP	MGI:MGI:2670143	Mouse	PMID:12853475
Biological Process	GO:0030048	actin filament-based movement	Wasf2	IMP	MGI:MGI:2670143	Mouse	PMID:12853475
Biological Process	GO:0001667	ameboidal-type cell migration	Wasf2	IMP	MGI:MGI:2670134	Mouse	PMID:12879075
Biological Process	GO:0001525	angiogenesis	Wasf2	IMP	MGI:MGI:2670134	Mouse	PMID:12879075
Biological Process	GO:0006897	endocytosis	Wasf2	IDA		Mouse	PMID:12446704
Biological Process	GO:0007507	heart development	wasf2	IMP	ZFIN:ZDB-CRISPR-201116-7	Zfish	PMID:32368696
Biological Process	GO:0030032	lamellipodium assembly	Wasf2	IMP	MGI:MGI:2670134	Mouse	PMID:12879075
Biological Process	GO:0072673	lamellipodium morphogenesis	Wasf2	IMP		Mouse	PMID:17664349
Biological Process	GO:0035855	megakaryocyte development	Wasf2	IMP		Mouse	PMID:17664349
Biological Process	GO:0051497	negative regulation of stress fiber assembly	WASF2	IMP		Human	PMID:21107423
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	WASF2	IMP		Human	PMID:18560548
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	WASF2	IMP		Human	PMID:21107423
Biological Process	GO:0099173	postsynapse organization	Wasf2	IMP		Mouse	PMID:15673667
Biological Process	GO:0099173	postsynapse organization	Wasf2	IDA		Mouse	PMID:15673667
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Wasf2	IMP		Mouse	PMID:15673667
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Wasf2	IDA		Mouse	PMID:15673667
Biological Process	GO:0016601	Rac protein signal transduction	Wasf2	IMP	MGI:MGI:2670143	Mouse	PMID:12853475

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern