Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WASH2P,WASH3P,WASH4P,WASH6P,WASHC1
  • Mouse genes Washc1
  • Rat genes Washc1
  • Zfish genes wash1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Washc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	WASHC1	IDA		Human	PMID:19922874
Molecular Function	GO:0043015	gamma-tubulin binding	Washc1	IDA		Mouse	MGI:MGI:4830083|PMID:20308062
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q9Y4E1	Human	PMID:19922874
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q14457	Human	PMID:23974797
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q8IYI6	Human	PMID:24344185
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q9NV70	Human	PMID:24344185
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:O75165	Human	PMID:24643499
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:O60826	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q567U6	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC1	IPI	UniProtKB:Q7Z3J2	Human	PMID:25355947
Molecular Function	GO:0031625	ubiquitin protein ligase binding	WASHC1	IPI	UniProtKB:P14373	Human	PMID:23452853
Cellular Component	GO:0005776	autophagosome	Washc1	IDA		Mouse	MGI:MGI:5519172|PMID:23974797
Cellular Component	GO:0031083	BLOC-1 complex	Washc1	IDA		Mouse	MGI:MGI:4830083|PMID:20308062
Cellular Component	GO:0005813	centrosome	Washc1	IDA		Mouse	MGI:MGI:4830083|PMID:20308062
Cellular Component	GO:0005769	early endosome	WASHC1	IDA		Human	PMID:19922874
Cellular Component	GO:0005769	early endosome	WASH3P	IDA		Human	PMID:20175130
Cellular Component	GO:0005769	early endosome	Washc1	IDA		Mouse	MGI:MGI:4415646|PMID:19922875
Cellular Component	GO:0005769	early endosome	Washc1	IDA		Mouse	PMID:27390154
Cellular Component	GO:0005768	endosome	Washc1	IDA		Mouse	PMID:26965651
Cellular Component	GO:0030175	filopodium	WASH3P	IDA		Human	PMID:18159949
Cellular Component	GO:0030027	lamellipodium	WASH3P	IDA		Human	PMID:18159949
Cellular Component	GO:0005770	late endosome	Washc1	IDA		Mouse	PMID:27390154
Cellular Component	GO:0055037	recycling endosome	WASH3P	IDA		Human	PMID:20175130
Cellular Component	GO:0055037	recycling endosome	Washc1	IDA		Mouse	MGI:MGI:4415646|PMID:19922875
Cellular Component	GO:0071203	WASH complex	WASHC1	IDA		Human	PMID:19922875
Cellular Component	GO:0071203	WASH complex	Washc1	IDA		Mouse	PMID:26965651
Cellular Component	GO:0071203	WASH complex	Washc1	IDA		Mouse	PMID:27390154
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	WASHC1	IDA		Human	PMID:23452853
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	WASH3P	IDA		Human	PMID:18159949
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	Washc1	IMP		Mouse	MGI:MGI:4415646|PMID:19922875
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	Washc1	IMP		Mouse	PMID:23452853
Biological Process	GO:0002468	dendritic cell antigen processing and presentation	Washc1	IMP		Mouse	MGI:MGI:5613771|PMID:24886983
Biological Process	GO:0045022	early endosome to late endosome transport	WASH3P	IMP		Human	PMID:20175130
Biological Process	GO:0032456	endocytic recycling	WASHC1	IMP		Human	PMID:22114305
Biological Process	GO:0032456	endocytic recycling	Washc1	IMP		Mouse	MGI:MGI:5613462|PMID:23275443
Biological Process	GO:0016197	endosomal transport	Washc1	IMP		Mouse	MGI:MGI:4415646|PMID:19922875
Biological Process	GO:0007032	endosome organization	WASH3P	IMP		Human	PMID:20175130
Biological Process	GO:0007032	endosome organization	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0099638	endosome to plasma membrane protein transport	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0099638	endosome to plasma membrane protein transport	Washc1	IDA		Mouse	PMID:26965651
Biological Process	GO:0006887	exocytosis	WASHC1	IMP		Human	PMID:24344185
Biological Process	GO:0022617	extracellular matrix disassembly	WASHC1	IMP		Human	PMID:24344185
Biological Process	GO:0034383	low-density lipoprotein particle clearance	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0090306	meiotic spindle assembly	Washc1	IMP		Mouse	MGI:MGI:5613746|PMID:24998208
Biological Process	GO:0010507	negative regulation of autophagy	Washc1	IMP		Mouse	MGI:MGI:5519172|PMID:23974797
Biological Process	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity	Washc1	IDA		Mouse	MGI:MGI:5519172|PMID:23974797
Biological Process	GO:0001556	oocyte maturation	Washc1	IMP		Mouse	MGI:MGI:5613746|PMID:24998208
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	Washc1	IMP		Mouse	MGI:MGI:5613746|PMID:24998208
Biological Process	GO:0030335	positive regulation of cell migration	WASHC1	IMP		Human	PMID:22114305
Biological Process	GO:1904109	positive regulation of cholesterol import	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	Washc1	IDA		Mouse	PMID:26965651
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0031274	positive regulation of pseudopodium assembly	WASHC1	IMP		Human	PMID:22114305
Biological Process	GO:0034394	protein localization to cell surface	Washc1	IMP		Mouse	MGI:MGI:5613462|PMID:23275443
Biological Process	GO:0034394	protein localization to cell surface	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0034394	protein localization to cell surface	Washc1	IDA		Mouse	PMID:26965651
Biological Process	GO:0006622	protein targeting to lysosome	WASH3P	IMP		Human	PMID:20175130
Biological Process	GO:0030833	regulation of actin filament polymerization	Washc1	IMP		Mouse	PMID:26965651
Biological Process	GO:0050776	regulation of immune response	Washc1	IMP		Mouse	MGI:MGI:5613462|PMID:23275443
Biological Process	GO:0031396	regulation of protein ubiquitination	Washc1	IDA		Mouse	MGI:MGI:5519172|PMID:23974797
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	WASHC1	IMP		Human	PMID:19922874
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	WASHC1	IDA		Human	PMID:23452853
Biological Process	GO:0042098	T cell proliferation	Washc1	IMP		Mouse	MGI:MGI:5613462|PMID:23275443

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern