Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR1
  • Mouse genes Wdr1
  • Rat genes Wdr1
  • Zfish genes wdr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Wdr1	IDA		Rat	PMID:20631256|RGD:8693352
Cellular Component	GO:0015629	actin cytoskeleton	Wdr1	IDA		Rat	PMID:20631256|RGD:8693352
Cellular Component	GO:0030054	cell junction	WDR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	WDR1	IDA		Human	PMID:25792565
Cellular Component	GO:0070062	extracellular exosome	WDR1	HDA		Human	PMID:19056867
Cellular Component	GO:0043209	myelin sheath	Wdr1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005886	plasma membrane	WDR1	IDA		Human	GO_REF:0000052
Biological Process	GO:0030036	actin cytoskeleton organization	Wdr1	IMP		Mouse	PMID:24840128
Biological Process	GO:0030043	actin filament fragmentation	Wdr1	IMP		Mouse	MGI:MGI:5787764|PMID:25915128
Biological Process	GO:0043297	apical junction assembly	WDR1	IDA		Human	PMID:25792565
Biological Process	GO:0030865	cortical cytoskeleton organization	Wdr1	IMP		Mouse	MGI:MGI:3784948|PMID:17515402
Biological Process	GO:0042247	establishment of planar polarity of follicular epithelium	Wdr1	IMP		Mouse	MGI:MGI:5787764|PMID:25915128
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	WDR1	IDA		Human	PMID:25792565
Biological Process	GO:0002446	neutrophil mediated immunity	Wdr1	IMP		Mouse	MGI:MGI:3784948|PMID:17515402
Biological Process	GO:1990266	neutrophil migration	Wdr1	IMP		Mouse	MGI:MGI:3784948|PMID:17515402
Biological Process	GO:0030220	platelet formation	Wdr1	IMP		Mouse	MGI:MGI:3784948|PMID:17515402
Biological Process	GO:0030836	positive regulation of actin filament depolymerization	Wdr1	IGI	MGI:MGI:101763	Mouse	PMID:24840128
Biological Process	GO:0030834	regulation of actin filament depolymerization	WDR1	IDA		Human	PMID:15629458
Biological Process	GO:0008360	regulation of cell shape	Wdr1	IMP		Mouse	MGI:MGI:5787764|PMID:25915128
Biological Process	GO:0048713	regulation of oligodendrocyte differentiation	Wdr1	IDA		Rat	PMID:20631256|RGD:8693352
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	Wdr1	IMP		Mouse	PMID:24840128
Biological Process	GO:0045214	sarcomere organization	Wdr1	IMP		Mouse	PMID:24840128

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern