Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR35
  • Mouse genes Wdr35
  • Rat genes Wdr35
  • Zfish genes wdr35
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr35

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WDR35	IPI	UniProtKB:Q96FT9	Human	PMID:27932497
Molecular Function	GO:0005515	protein binding	WDR35	IPI	UniProtKB:Q96FT9,UniProtKB:Q9HBG6	Human	PMID:29220510
Cellular Component	GO:0005930	axoneme	Wdr35	IDA		Mouse	MGI:MGI:4950635|PMID:21473986
Cellular Component	GO:0005813	centrosome	Wdr35	IDA		Mouse	MGI:MGI:4950635|PMID:21473986
Cellular Component	GO:0036064	ciliary basal body	Wdr35	IDA		Mouse	MGI:MGI:4950635|PMID:21473986
Cellular Component	GO:0005737	cytoplasm	Wdr35	IDA		Rat	PMID:18472094|RGD:11553927
Cellular Component	GO:0030991	intraciliary transport particle A	WDR35	IPI		Human	PMID:27173435
Cellular Component	GO:0030991	intraciliary transport particle A	WDR35	IDA		Human	PMID:20889716
Cellular Component	GO:0030991	intraciliary transport particle A	WDR35	IDA		Human	PMID:27932497
Cellular Component	GO:0030991	intraciliary transport particle A	Wdr35	IDA		Mouse	PMID:20889716
Biological Process	GO:0071333	cellular response to glucose stimulus	Wdr35	IEP		Rat	PMID:20224876|RGD:11553923
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Wdr35	IEP		Mouse	PMID:20439489
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Wdr35	IMP		Rat	PMID:20193664|RGD:11553917
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Wdr35	IEP		Rat	PMID:18472094|RGD:11553927
Biological Process	GO:0060271	cilium assembly	WDR35	IMP		Human	PMID:21473986
Biological Process	GO:0060271	cilium assembly	Wdr35	IMP		Mouse	MGI:MGI:4950635|PMID:21473986
Biological Process	GO:0060271	cilium assembly	wdr35	IMP	ZFIN:ZDB-GENO-160908-9	Zfish	PMID:27207957
Biological Process	GO:0035721	intraciliary retrograde transport	WDR35	IMP		Human	PMID:20889716
Biological Process	GO:0042073	intraciliary transport	WDR35	IMP		Human	PMID:29220510
Biological Process	GO:0097421	liver regeneration	Wdr35	IEP		Rat	PMID:18472094|RGD:11553927
Biological Process	GO:0010629	negative regulation of gene expression	Wdr35	IDA		Rat	PMID:18671723|RGD:11553926
Biological Process	GO:0010629	negative regulation of gene expression	Wdr35	IMP		Rat	PMID:23289926|RGD:11553920
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	Wdr35	IDA		Rat	PMID:18671723|RGD:11553926
Biological Process	GO:0043065	positive regulation of apoptotic process	Wdr35	IMP		Rat	PMID:20193664|RGD:11553917
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Wdr35	IMP		Rat	PMID:20193664|RGD:11553917
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	Wdr35	IMP		Rat	PMID:23289926|RGD:11553920
Biological Process	GO:0045907	positive regulation of vasoconstriction	Wdr35	IDA		Rat	PMID:18671723|RGD:11553926
Biological Process	GO:0061512	protein localization to cilium	WDR35	IMP		Human	PMID:29220510
Biological Process	GO:0032496	response to lipopolysaccharide	Wdr35	IEP		Rat	PMID:24803807|RGD:11553919
Biological Process	GO:0009636	response to toxic substance	Wdr35	IEP		Rat	PMID:23289926|RGD:11553920

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern