Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR43
  • Mouse genes Wdr43
  • Rat genes Wdr43
  • Zfish genes wdr43
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr43

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WDR43	IPI	UniProtKB:Q969X6	Human	PMID:22916032
Molecular Function	GO:0005515	protein binding	WDR43	IPI	UniProtKB:Q969X6	Human	PMID:24219289
Molecular Function	GO:0005515	protein binding	WDR43	IPI	UniProtKB:Q969X6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Wdr43	IPI	UniProtKB:Q62383|UniProtKB:Q99J95|UniProtKB:Q9JIK5	Mouse	MGI:MGI:6323527|PMID:31128943
Molecular Function	GO:0003723	RNA binding	WDR43	HDA		Human	PMID:22658674
Molecular Function	GO:0000993	RNA polymerase II complex binding	Wdr43	IDA		Mouse	MGI:MGI:6323527|PMID:31128943
Molecular Function	GO:0003711	transcription elongation factor activity	Wdr43	IMP		Mouse	MGI:MGI:6323527|PMID:31128943
Cellular Component	GO:0000785	chromatin	Wdr43	IDA		Mouse	MGI:MGI:6323527|PMID:31128943
Cellular Component	GO:0001650	fibrillar center	WDR43	IDA		Human	PMID:24219289
Cellular Component	GO:0005730	nucleolus	WDR43	IDA		Human	PMID:17699751
Cellular Component	GO:0005730	nucleolus	WDR43	IDA		Human	PMID:24219289
Cellular Component	GO:0005730	nucleolus	Wdr43	IDA		Mouse	MGI:MGI:6323527|PMID:31128943
Cellular Component	GO:0005654	nucleoplasm	Wdr43	IDA		Mouse	MGI:MGI:6323527|PMID:31128943
Biological Process	GO:0001525	angiogenesis	wdr43	IMP	ZFIN:ZDB-GENO-090730-3	Zfish	PMID:19332767
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	wdr43	IMP	ZFIN:ZDB-GENO-150219-15	Zfish	PMID:24497835
Biological Process	GO:0060218	hematopoietic stem cell differentiation	wdr43	IMP	ZFIN:ZDB-GENO-090730-3	Zfish	PMID:19332767
Biological Process	GO:2000234	positive regulation of rRNA processing	WDR43	IMP		Human	PMID:17699751
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	WDR43	IMP		Human	PMID:17699751
Biological Process	GO:2000036	regulation of stem cell population maintenance	Wdr43	IMP		Mouse	MGI:MGI:6323527|PMID:31128943
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	Wdr43	IMP		Mouse	MGI:MGI:6323527|PMID:31128943
Biological Process	GO:0042254	ribosome biogenesis	wdr43	IMP	ZFIN:ZDB-GENO-150219-15	Zfish	PMID:24497835
Biological Process	GO:0001570	vasculogenesis	wdr43	IMP	ZFIN:ZDB-GENO-090730-3	Zfish	PMID:19332767

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern