Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR48
  • Mouse genes Wdr48
  • Rat genes Wdr48
  • Zfish genes wdr48a,wdr48b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr48

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035800	deubiquitinase activator activity	WDR48	IDA		Human	PMID:18082604
Molecular Function	GO:0035800	deubiquitinase activator activity	WDR48	IDA		Human	PMID:19075014
Molecular Function	GO:0035800	deubiquitinase activator activity	WDR48	IDA		Human	PMID:24145035
Molecular Function	GO:0035800	deubiquitinase activator activity	WDR48	IDA		Human	PMID:31253762
Molecular Function	GO:0003677	DNA binding	WDR48	IDA		Human	PMID:31253762
Molecular Function	GO:0003690	double-stranded DNA binding	WDR48	IDA		Human	PMID:27239033
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:O94782	Human	PMID:18082604
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:O75317	Human	PMID:19075014
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:P62068	Human	PMID:19075014
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:O60346	Human	PMID:24145035
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:Q96B01	Human	PMID:27239033
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:O75317	Human	PMID:27373336
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:Q96B01	Human	PMID:27463890
Molecular Function	GO:0005515	protein binding	WDR48	IPI	UniProtKB:O75317	Human	PMID:27650958
Molecular Function	GO:0003697	single-stranded DNA binding	WDR48	IDA		Human	PMID:27239033
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	WDR48	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	WDR48	IDA		Human	PMID:18082604
Biological Process	GO:0006974	DNA damage response	WDR48	IDA		Human	PMID:27239033
Biological Process	GO:0006974	DNA damage response	WDR48	IDA		Human	PMID:27463890
Biological Process	GO:0006974	DNA damage response	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0048568	embryonic organ development	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0048872	homeostasis of number of cells	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0008584	male gonad development	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0035264	multicellular organism growth	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	WDR48	IDA		Human	PMID:27239033
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	WDR48	IDA		Human	PMID:27463890
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:1902525	regulation of protein monoubiquitination	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0072520	seminiferous tubule development	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0007338	single fertilization	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0048705	skeletal system morphogenesis	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0043588	skin development	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775
Biological Process	GO:0007283	spermatogenesis	Wdr48	IMP	MGI:MGI:3877670	Mouse	PMID:24001775

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern