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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Wdr5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr5
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0042800histone H3K4 methyltransferase activityWdr5IMPMousePMID:24051374
Molecular FunctionGO:0035064methylated histone bindingWDR5IDAHumanPMID:16600877
Molecular FunctionGO:0035064methylated histone bindingWDR5IDAHumanPMID:18840606
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P51610HumanPMID:12670868
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O00255HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P51610HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z3B3HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9HCK8HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P54259HumanPMID:16713569
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P68431HumanPMID:16946699
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:17021013
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:17041588
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:17178841
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15550HumanPMID:17178841
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:17178841
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:17178841
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:17500065
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:17500065
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:17500065
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:17500065
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NEZ4HumanPMID:17500065
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:17925232
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:17925232
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:17925232
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15047HumanPMID:17998332
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9HCK8HumanPMID:18378692
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:18840606
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:18840606
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:19047629
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:19433796
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:19556245
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:19556245
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q13114HumanPMID:20080758
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z434-1HumanPMID:20080758
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9Y4K3HumanPMID:20080758
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9HCK8HumanPMID:20085832
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164:PRO_0000390950HumanPMID:20581860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q92794HumanPMID:20581860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:20818375
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NYB0HumanPMID:21044950
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:21220120
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:21220120
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:22266653
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15047HumanPMID:22266653
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NEZ4HumanPMID:22266653
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:22266653
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UPS6HumanPMID:22266653
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15047HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NEZ4HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UPS6HumanPMID:22665483
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9WTL8HumanPMID:23555304
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:23870121
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:23870121
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O43823HumanPMID:23995757
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:23995757
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P68431HumanPMID:24788516
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z3B3HumanPMID:24788516
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9H9L4HumanPMID:24788516
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:24788516
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O00255HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15550HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P51610HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P54259HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z3B3HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8IYH5HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NEZ4HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NFC6HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9H9L4HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:A2RRG2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03933HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9H891HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73-5HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9Y2D8HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O00255HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O14686HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15550HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P51610HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P54259HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03164HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q15291HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q2QGD7HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6PEV8HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z3B3HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8IYH5HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NEZ4HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NFC6HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9H9L4HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P54259HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14686HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6ZW49HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q7Z3B3HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q8NFC6HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73-5HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UMN6HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q2QGD7HumanPMID:29892012
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03933HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:A7MD48HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O00308HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O15151HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:O76083-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:P10074HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q03933HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q2QGD7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6FHY5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q6PEV8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q96PG8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9NS73HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9UJX6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9Y4F3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q9Y5X4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q14204HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q86V38HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingWDR5IPIUniProtKB:Q92876HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingWdr5IPIUniProtKB:P20263MouseMGI:MGI:5285127|PMID:21477851
Molecular FunctionGO:0005515protein bindingWdr5IPIUniProtKB:P20263MouseMGI:MGI:5320277|PMID:20362541
Molecular FunctionGO:0005515protein bindingWdr5IPIPR:Q8CID0MousePMID:19103755
Molecular FunctionGO:0005515protein bindingWdr5IPIPR:Q9JHD2MousePMID:19103755
Molecular FunctionGO:0005515protein bindingWdr5IPIUniProtKB:Q6P5F4MousePMID:23178126
Molecular FunctionGO:0005515protein bindingWdr5IPIPR:P58501MousePMID:22862948
Molecular FunctionGO:0005515protein bindingWdr5IPIMGI:MGI:1916161MousePMID:19487454
Molecular FunctionGO:0005515protein bindingWdr5IPIPR:Q99LQ1MousePMID:19103755
Molecular FunctionGO:0005515protein bindingWdr5IPIPR:Q91WV0MousePMID:19103755
Molecular FunctionGO:0005515protein bindingWdr5IPIUniProtKB:Q8CHI5RatPMID:15860628|RGD:1579815
Molecular FunctionGO:0005515protein bindingWdr5IPIRGD:1564494RatPMID:21816345|RGD:9587469
Molecular FunctionGO:0005515protein bindingWdr5IPIUniProtKB:A0A0G2K916,UniProtKB:B2GV38,UniProtKB:B5DFN4,UniProtKB:D3Z941,UniProtKB:D4AA63,UniProtKB:F1M853,UniProtKB:P11250,UniProtKB:P51593,UniProtKB:P61107,UniProtKB:P62718,UniProtKB:P97612,UniProtKB:Q09167,UniProtKB:Q5PPJ6,UniProtKB:Q5PPK9,UniProtKB:Q63569,UniProtKB:Q6AYJ7RatPMID:27191843|RGD:11344934
Molecular FunctionGO:0005515protein bindingwdr5IPIUniProtKB:B0S733ZfishPMID:30944473|ZFIN:ZDB-PUB-190405-14
Molecular FunctionGO:0005515protein bindingwdr5IPIUniProtKB:F1QST7ZfishPMID:30944473|ZFIN:ZDB-PUB-190405-14
Molecular FunctionGO:0005515protein bindingwdr5IPIZFIN:ZDB-GENE-060721-2ZfishPMID:30944473
Cellular ComponentGO:0140672ATAC complexWDR5IDAHumanPMID:19936620
Cellular ComponentGO:0140672ATAC complexWDR5IDAHumanPMID:18838386
Cellular ComponentGO:0140672ATAC complexWdr5IDAMouseMGI:MGI:6827473|PMID:19936620
Cellular ComponentGO:0000123histone acetyltransferase complexWDR5IDAHumanPMID:20018852
Cellular ComponentGO:0035097histone methyltransferase complexWDR5IDAHumanPMID:17355966
Cellular ComponentGO:0035097histone methyltransferase complexWDR5IDAHumanPMID:17500065
Cellular ComponentGO:0035097histone methyltransferase complexWDR5IDAHumanPMID:19556245
Cellular ComponentGO:0005622intracellular anatomical structureWdr5IDAMousePMID:11551928
Cellular ComponentGO:0071339MLL1 complexWDR5IPIHumanPMID:23508102
Cellular ComponentGO:0071339MLL1 complexWDR5IDAHumanPMID:15960975
Cellular ComponentGO:0044665MLL1/2 complexWDR5IPIHumanPMID:23508102
Cellular ComponentGO:0044666MLL3/4 complexWDR5IPIHumanPMID:23508102
Cellular ComponentGO:0044666MLL3/4 complexWDR5IDAHumanPMID:17500065
Cellular ComponentGO:0044545NSL complexWDR5IDAHumanPMID:20018852
Cellular ComponentGO:0005654nucleoplasmWDR5IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusWDR5IDAHumanPMID:17500065
Cellular ComponentGO:0005634nucleusWdr5IDAMouseMGI:MGI:5567916|PMID:15860628
Cellular ComponentGO:0005634nucleusWdr5IDAMousePMID:19103755
Cellular ComponentGO:0005634nucleusWdr5IDAMousePMID:22514746
Cellular ComponentGO:0005634nucleusWdr5IDARatPMID:21816345|RGD:9587469
Cellular ComponentGO:0032991protein-containing complexwdr5IPIZFIN:ZDB-GENE-060721-2,ZFIN:ZDB-GENE-040426-886ZfishPMID:30944473
Cellular ComponentGO:0048188Set1C/COMPASS complexWDR5IPIHumanPMID:23508102
Cellular ComponentGO:0048188Set1C/COMPASS complexWDR5IDAHumanPMID:17998332
Cellular ComponentGO:0048188Set1C/COMPASS complexWDR5IDAHumanPMID:18838538
Biological ProcessGO:0006094gluconeogenesisWdr5IGIMGI:MGI:95674MousePMID:24051374
Biological ProcessGO:0006094gluconeogenesisWdr5IGIMGI:MGI:1343094MousePMID:24051374
Biological ProcessGO:0043966histone H3 acetylationWDR5IDAHumanPMID:18838386
Biological ProcessGO:0044154histone H3-K14 acetylationWDR5IDAHumanPMID:19936620
Biological ProcessGO:0043984histone H4-K16 acetylationWDR5IDAHumanPMID:20018852
Biological ProcessGO:0043981histone H4-K5 acetylationWDR5IDAHumanPMID:20018852
Biological ProcessGO:0043982histone H4-K8 acetylationWDR5IDAHumanPMID:20018852
Biological ProcessGO:0031175neuron projection developmentWdr5IDARatPMID:21816345|RGD:9587469
Biological ProcessGO:0018022peptidyl-lysine methylationWdr5IMPMousePMID:24051374
Biological ProcessGO:0045722positive regulation of gluconeogenesisWdr5IGIMGI:MGI:95674MousePMID:24051374
Biological ProcessGO:0045722positive regulation of gluconeogenesisWdr5IGIMGI:MGI:1343094MousePMID:24051374
Biological ProcessGO:0051571positive regulation of histone H3-K4 methylationWDR5IDAHumanPMID:24244196
Biological ProcessGO:0051726regulation of cell cycleWDR5IMPHumanPMID:19103755
Biological ProcessGO:0051726regulation of cell cycleWdr5IMPMouseMGI:MGI:3835889|PMID:19103755
Biological ProcessGO:0051302regulation of cell divisionWDR5IDAHumanPMID:20562830
Biological ProcessGO:0051302regulation of cell divisionWdr5IDAMouseMGI:MGI:4462728|PMID:20562830
Biological ProcessGO:0006355regulation of DNA-templated transcriptionWDR5IMPHumanPMID:19936620
Biological ProcessGO:1900095regulation of dosage compensation by inactivation of X chromosomeWdr5IDAMouseMGI:MGI:6207704|PMID:24842875
Biological ProcessGO:0045995regulation of embryonic developmentWdr5IDAMouseMGI:MGI:3835889|PMID:19103755
Biological ProcessGO:0031063regulation of histone deacetylationWDR5IMPHumanPMID:20562830
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIWDR5IDAHumanPMID:22055187
Biological ProcessGO:0090043regulation of tubulin deacetylationWDR5IMPHumanPMID:20562830
Biological ProcessGO:0001501skeletal system developmentWdr5IDAMousePMID:11551928
Biological ProcessGO:0045815transcription initiation-coupled chromatin remodelingWDR5IDAHumanPMID:19556245

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory