Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR74
  • Mouse genes Wdr74
  • Rat genes Wdr74
  • Zfish genes wdr74
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr74

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WDR74	IPI	UniProtKB:Q96PM5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WDR74	IPI	UniProtKB:P42285	Human	PMID:26456651
Molecular Function	GO:0005515	protein binding	WDR74	IPI	UniProtKB:O15381	Human	PMID:28416111
Molecular Function	GO:0005515	protein binding	WDR74	IPI	UniProtKB:P42285	Human	PMID:29107693
Cellular Component	GO:0005730	nucleolus	WDR74	IDA		Human	PMID:26456651
Cellular Component	GO:0005730	nucleolus	WDR74	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	WDR74	IDA		Human	PMID:12429849
Cellular Component	GO:0005730	nucleolus	WDR74	IDA		Human	PMID:28416111
Cellular Component	GO:0005730	nucleolus	WDR74	IMP		Human	PMID:29107693
Cellular Component	GO:0005654	nucleoplasm	WDR74	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	WDR74	IDA		Human	PMID:28416111
Cellular Component	GO:0005634	nucleus	Wdr74	IDA		Mouse	PMID:21799883
Biological Process	GO:0001825	blastocyst formation	Wdr74	IMP		Mouse	PMID:21799883
Biological Process	GO:0001825	blastocyst formation	Wdr74	IMP		Mouse	PMID:27869233
Biological Process	GO:0042273	ribosomal large subunit biogenesis	WDR74	IMP		Human	PMID:26456651
Biological Process	GO:0016070	RNA metabolic process	Wdr74	IMP		Mouse	PMID:21799883
Biological Process	GO:0006364	rRNA processing	WDR74	IMP		Human	PMID:29107693

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern