Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WLS
  • Mouse genes Wls
  • Rat genes Wls
  • Zfish genes wls
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wls

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031852	mu-type opioid receptor binding	Wls	IPI	RGD:3234	Rat	PMID:20214800|RGD:7488961
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:Q96QK1	Human	PMID:18160348
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:Q9EQH3	Human	PMID:18160348
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:P35372	Human	PMID:20214800
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:P56704	Human	PMID:22784633
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:P35372	Human	PMID:23840749
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:P56704	Human	PMID:24768165
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:P35372	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	WLS	IPI	UniProtKB:Q01959	Human	PMID:28734904
Molecular Function	GO:0005515	protein binding	Wls	IPI	UniProtKB:P04426	Mouse	MGI:MGI:4397730|PMID:19841259
Molecular Function	GO:0005515	protein binding	Wls	IPI	UniProtKB:P04426|UniProtKB:P17553|UniProtKB:P22725	Mouse	MGI:MGI:4397730|PMID:19841259
Molecular Function	GO:0005515	protein binding	Wls	IPI	PR:P22725	Mouse	PMID:33324648
Molecular Function	GO:0005515	protein binding	Wls	IPI	PR:Q922P8	Mouse	PMID:33324648
Molecular Function	GO:0005515	protein binding	Wls	IPI	PR:P27467	Mouse	PMID:33324648
Molecular Function	GO:0005515	protein binding	Wls	IPI	UniProtKB:P33535	Rat	PMID:20214800|RGD:7488961
Molecular Function	GO:0017147	Wnt-protein binding	WLS	IPI	UniProtKB:P56704	Human	PMID:24768165
Molecular Function	GO:0017147	Wnt-protein binding	Wls	IDA		Mouse	MGI:MGI:4397730|PMID:19841259
Cellular Component	GO:0031410	cytoplasmic vesicle	WLS	IDA		Human	PMID:16678095
Cellular Component	GO:0031410	cytoplasmic vesicle	Wls	IDA		Mouse	MGI:MGI:4397730|PMID:19841259
Cellular Component	GO:0005829	cytosol	WLS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032839	dendrite cytoplasm	Wls	IDA		Rat	PMID:22001156|RGD:7488965
Cellular Component	GO:0032590	dendrite membrane	Wls	IDA		Rat	PMID:22001156|RGD:7488965
Cellular Component	GO:0005769	early endosome	WLS	IDA		Human	PMID:18160348
Cellular Component	GO:0005783	endoplasmic reticulum	WLS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	Wls	IDA		Mouse	PMID:33324648
Cellular Component	GO:0005794	Golgi apparatus	WLS	IDA		Human	PMID:16678095
Cellular Component	GO:0005794	Golgi apparatus	Wls	IDA		Mouse	MGI:MGI:4397730|PMID:19841259
Cellular Component	GO:0005886	plasma membrane	WLS	IDA		Human	PMID:18160348
Cellular Component	GO:0005886	plasma membrane	Wls	IDA		Mouse	PMID:33324648
Cellular Component	GO:0005802	trans-Golgi network	WLS	IDA		Human	PMID:18160348
Biological Process	GO:0009948	anterior/posterior axis specification	Wls	IMP		Mouse	MGI:MGI:4397730|PMID:19841259
Biological Process	GO:0060536	cartilage morphogenesis	wls	IMP	ZFIN:ZDB-GENO-180116-1	Zfish	PMID:27908786
Biological Process	GO:0071529	cementum mineralization	Wls	IGI	MGI:MGI:2153568	Mouse	PMID:31059863
Biological Process	GO:0071529	cementum mineralization	Wls	IGI	MGI:MGI:97370	Mouse	PMID:31059863
Biological Process	GO:0044566	chondrocyte activation	wls	IMP	ZFIN:ZDB-GENO-180501-2	Zfish	PMID:27287801
Biological Process	GO:0035988	chondrocyte proliferation	wls	IMP	ZFIN:ZDB-GENO-180116-7	Zfish	PMID:27908786
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	wls	IMP	ZFIN:ZDB-MRPHLNO-101011-2	Zfish	PMID:25934698
Biological Process	GO:0001958	endochondral ossification	wls	IMP	ZFIN:ZDB-GENO-180116-1	Zfish	PMID:27908786
Biological Process	GO:0031017	exocrine pancreas development	Wls	IMP		Mouse	MGI:MGI:4834980|PMID:20614471
Biological Process	GO:0021986	habenula development	wls	IMP	ZFIN:ZDB-GENO-180116-1	Zfish	PMID:28619821
Biological Process	GO:0021986	habenula development	wls	IMP	ZFIN:ZDB-GENO-160215-1	Zfish	PMID:26116173
Biological Process	GO:0030902	hindbrain development	Wls	IMP		Mouse	MGI:MGI:4834980|PMID:20614471
Biological Process	GO:0006886	intracellular protein transport	WLS	IMP		Human	PMID:16678095
Biological Process	GO:0001957	intramembranous ossification	wls	IMP	ZFIN:ZDB-GENO-180116-1	Zfish	PMID:27908786
Biological Process	GO:0001707	mesoderm formation	Wls	IMP		Mouse	MGI:MGI:4397730|PMID:19841259
Biological Process	GO:0030901	midbrain development	Wls	IMP		Mouse	MGI:MGI:4834980|PMID:20614471
Biological Process	GO:0030917	midbrain-hindbrain boundary development	wls	IMP	ZFIN:ZDB-MRPHLNO-101011-3	Zfish	PMID:20652957
Biological Process	GO:0030917	midbrain-hindbrain boundary development	wls	IMP	ZFIN:ZDB-MRPHLNO-101011-2	Zfish	PMID:20652957
Biological Process	GO:0001503	ossification	wls	IMP	ZFIN:ZDB-GENO-180116-1	Zfish	PMID:27908786
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	WLS	IMP		Human	PMID:17804805
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Wls	IMP		Mouse	MGI:MGI:4834980|PMID:20614471
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Wls	IMP		Rat	PMID:25424568|RGD:11060597
Biological Process	GO:0061357	positive regulation of Wnt protein secretion	WLS	IMP		Human	PMID:16678095
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	WLS	IMP		Human	PMID:16678095
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	WLS	IMP		Human	PMID:16678096
Biological Process	GO:0060872	semicircular canal development	wls	IMP	ZFIN:ZDB-MRPHLNO-101011-2	Zfish	PMID:20652957
Biological Process	GO:0060872	semicircular canal development	wls	IMP	ZFIN:ZDB-MRPHLNO-101011-3	Zfish	PMID:20652957
Biological Process	GO:0061355	Wnt protein secretion	WLS	IMP		Human	PMID:24768165
Biological Process	GO:0061355	Wnt protein secretion	Wls	IDA		Mouse	PMID:33324648
Biological Process	GO:0016055	Wnt signaling pathway	Wls	IMP		Mouse	MGI:MGI:4397730|PMID:19841259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern