Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT10B
  • Mouse genes Wnt10b
  • Rat genes Wnt10b
  • Zfish genes wnt10b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt10b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WNT10B	IPI	UniProtKB:P05067	Human	PMID:32814053
Biological Process	GO:0042640	anagen	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0060346	bone trabecula formation	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15728361
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT10B	IDA		Human	PMID:17761539
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt10b	IDA		Mouse	PMID:10937998
Biological Process	GO:0008283	cell population proliferation	Wnt10b	IDA		Mouse	PMID:9160667
Biological Process	GO:0071320	cellular response to cAMP	Wnt10b	IDA		Mouse	PMID:12055200
Biological Process	GO:0071464	cellular response to hydrostatic pressure	Wnt10b	IEP		Rat	PMID:19118527|RGD:2326236
Biological Process	GO:0071407	cellular response to organic cyclic compound	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0071310	cellular response to organic substance	Wnt10b	IDA		Mouse	PMID:12055200
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0002062	chondrocyte differentiation	WNT10B	IEP		Human	PMID:15135146
Biological Process	GO:0030855	epithelial cell differentiation	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0045444	fat cell differentiation	Wnt10b	IDA		Mouse	PMID:12055200
Biological Process	GO:0045444	fat cell differentiation	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0061196	fungiform papilla development	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:17284610
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	Wnt10b	IGI	MGI:MGI:1351663	Mouse	PMID:19056892
Biological Process	GO:0071425	hematopoietic stem cell proliferation	WNT10B	IDA		Human	PMID:9787155
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Wnt10b	IDA		Mouse	PMID:9160667
Biological Process	GO:0006629	lipid metabolic process	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0030917	midbrain-hindbrain boundary development	wnt10b	IGI	ZFIN:ZDB-MRPHLNO-060705-3,ZFIN:ZDB-MRPHLNO-060705-4	Zfish	PMID:12591239
Biological Process	GO:0048627	myoblast development	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Wnt10b	IMP		Mouse	MGI:MGI:3052566|PMID:15190075
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0045599	negative regulation of fat cell differentiation	WNT10B	IDA		Human	PMID:10937998
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Wnt10b	IDA		Mouse	PMID:12055200
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Wnt10b	IDA		Mouse	PMID:10937998
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:15673614
Biological Process	GO:0001649	osteoblast differentiation	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0043065	positive regulation of apoptotic process	WNT10B	IMP		Human	PMID:17761539
Biological Process	GO:0030501	positive regulation of bone mineralization	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:1902035	positive regulation of hematopoietic stem cell proliferation	Wnt10b	IDA		Mouse	PMID:9160667
Biological Process	GO:0045778	positive regulation of ossification	Wnt10b	IMP		Mouse	PMID:17708715
Biological Process	GO:0045778	positive regulation of ossification	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15728361
Biological Process	GO:0045778	positive regulation of ossification	Wnt10b	IGI	MGI:MGI:98578	Mouse	PMID:19723499
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:0045582	positive regulation of T cell differentiation	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0051885	positive regulation of timing of anagen	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:15728361
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:17284610
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:15673614
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:9769173
Biological Process	GO:0050821	protein stabilization	WNT10B	IDA		Human	PMID:10937998
Biological Process	GO:0051726	regulation of cell cycle	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:0045598	regulation of fat cell differentiation	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	Wnt10b	IDA		Mouse	PMID:19056892
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:19056892
Biological Process	GO:0051246	regulation of protein metabolic process	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:19056892
Biological Process	GO:0051246	regulation of protein metabolic process	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15728361
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Wnt10b	IDA		Mouse	PMID:18155657
Biological Process	GO:0050909	sensory perception of taste	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:17284610
Biological Process	GO:0048741	skeletal muscle fiber development	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:15673614
Biological Process	GO:0007224	smoothened signaling pathway	Wnt10b	IDA		Mouse	PMID:17284610
Biological Process	GO:0030217	T cell differentiation	Wnt10b	IDA		Mouse	PMID:19723499
Biological Process	GO:0006366	transcription by RNA polymerase II	Wnt10b	IMP	MGI:MGI:3582610	Mouse	PMID:17284610
Biological Process	GO:0016055	Wnt signaling pathway	Wnt10b	IGI	MGI:MGI:108571	Mouse	PMID:11092808

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern