Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT11
  • Mouse genes Wnt11
  • Rat genes Wnt11
  • Zfish genes wnt11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	WNT11	IMP		Human	PMID:20103596
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q99750	Human	PMID:30886144
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:A6NK89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:O75690	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:O95273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q6L8G8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q9BTY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q9BYP8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WNT11	IPI	UniProtKB:Q9BYS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Wnt11	IPI	PR:Q9D1D6	Mouse	PMID:18606138
Molecular Function	GO:0030295	protein kinase activator activity	WNT11	IMP		Human	PMID:20103596
Molecular Function	GO:0030295	protein kinase activator activity	WNT11	IMP		Human	PMID:20219091
Cellular Component	GO:0005737	cytoplasm	WNT11	IDA		Human	PMID:20103596
Cellular Component	GO:0005737	cytoplasm	WNT11	IDA		Human	PMID:20219091
Cellular Component	GO:0031012	extracellular matrix	Wnt11	IDA		Mouse	PMID:8700530
Cellular Component	GO:0005576	extracellular region	Wnt11	IDA		Mouse	PMID:18155657
Biological Process	GO:0030325	adrenal gland development	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0006915	apoptotic process	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0048844	artery morphogenesis	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158
Biological Process	GO:0003283	atrial septum development	Wnt11	IGI	UniProtKB:P22725	Mouse	MGI:MGI:5424267|PMID:22569553
Biological Process	GO:0070830	bicellular tight junction assembly	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158
Biological Process	GO:0030282	bone mineralization	Wnt11	IGI	MGI:MGI:88177	Mouse	PMID:19213727
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt11	IDA		Mouse	PMID:19213727
Biological Process	GO:0030154	cell differentiation	Wnt11	IEP		Rat	PMID:16909041|RGD:2317898
Biological Process	GO:0042074	cell migration involved in gastrulation	wnt11	IMP	ZFIN:ZDB-MRPHLNO-050318-5	Zfish	PMID:15630025
Biological Process	GO:0042074	cell migration involved in gastrulation	wnt11	IMP	ZFIN:ZDB-MRPHLNO-050318-4	Zfish	PMID:15630025
Biological Process	GO:0071260	cellular response to mechanical stimulus	Wnt11	IDA		Mouse	PMID:25959411
Biological Process	GO:0060197	cloacal septation	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0060028	convergent extension involved in axis elongation	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0048706	embryonic skeletal system development	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	wnt11	IGI	ZFIN:ZDB-GENO-141212-7	Zfish	PMID:23375584
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	wnt11	IMP	ZFIN:ZDB-GENO-110722-33	Zfish	PMID:23375584
Biological Process	GO:1904019	epithelial cell apoptotic process	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0001837	epithelial to mesenchymal transition	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0007507	heart development	wnt11	IGI	ZFIN:ZDB-MRPHLNO-050318-1,ZFIN:ZDB-MRPHLNO-050318-3,ZFIN:ZDB-MRPHLNO-050318-4	Zfish	PMID:15630025
Biological Process	GO:0001947	heart looping	wnt11	IGI	ZFIN:ZDB-GENO-980202-1096	Zfish	PMID:23533583
Biological Process	GO:0001947	heart looping	wnt11	IGI	ZFIN:ZDB-GENO-130508-3	Zfish	PMID:23533583
Biological Process	GO:0001822	kidney development	Wnt11	IDA		Mouse	PMID:21281623
Biological Process	GO:0060484	lung-associated mesenchyme development	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0010463	mesenchymal cell proliferation	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0072177	mesonephric duct development	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0043066	negative regulation of apoptotic process	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Wnt11	IDA		Mouse	PMID:18155657
Biological Process	GO:0060548	negative regulation of cell death	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0030308	negative regulation of cell growth	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0030336	negative regulation of cell migration	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0090272	negative regulation of fibroblast growth factor production	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0072201	negative regulation of mesenchymal cell proliferation	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0061101	neuroendocrine cell differentiation	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0048884	neuromast development	wnt11	IMP	ZFIN:ZDB-GENO-200617-2	Zfish	PMID:31488837
Biological Process	GO:0048884	neuromast development	wnt11	IGI	ZFIN:ZDB-GENE-020507-3	Zfish	PMID:31488837
Biological Process	GO:0048884	neuromast development	wnt11	IGI	ZFIN:ZDB-GENO-200617-6	Zfish	PMID:31488837
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158
Biological Process	GO:0048570	notochord morphogenesis	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0001649	osteoblast differentiation	Wnt11	IGI	MGI:MGI:1922667	Mouse	PMID:19213727
Biological Process	GO:0001649	osteoblast differentiation	Wnt11	IGI	MGI:MGI:88177	Mouse	PMID:19213727
Biological Process	GO:0003151	outflow tract morphogenesis	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158
Biological Process	GO:0048341	paraxial mesoderm formation	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0060037	pharyngeal system development	wnt11	IGI	ZFIN:ZDB-GENE-030805-5	Zfish	PMID:25142463
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0060775	planar cell polarity pathway involved in gastrula mediolateral intercalation	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0043065	positive regulation of apoptotic process	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0030335	positive regulation of cell migration	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	WNT11	IMP		Human	PMID:19847889
Biological Process	GO:1904037	positive regulation of epithelial cell apoptotic process	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0010628	positive regulation of gene expression	WNT11	IMP		Human	PMID:20219091
Biological Process	GO:0043547	positive regulation of GTPase activity	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	Wnt11	IGI	UniProtKB:P22725	Mouse	MGI:MGI:5424267|PMID:22569553
Biological Process	GO:0090037	positive regulation of protein kinase C signaling	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0051496	positive regulation of stress fiber assembly	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0032915	positive regulation of transforming growth factor beta2 production	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158
Biological Process	GO:0003138	primary heart field specification	Wnt11	IGI	UniProtKB:P22725	Mouse	MGI:MGI:5424267|PMID:22569553
Biological Process	GO:0034394	protein localization to cell surface	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0006468	protein phosphorylation	WNT11	IMP		Human	PMID:20103596
Biological Process	GO:0031667	response to nutrient levels	Wnt11	IEP		Rat	PMID:18639218|RGD:2316744
Biological Process	GO:0060021	roof of mouth development	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0003139	secondary heart field specification	Wnt11	IGI	UniProtKB:P22725	Mouse	MGI:MGI:5424267|PMID:22569553
Biological Process	GO:0062009	secondary palate development	WNT11	IMP		Human	PMID:18413325
Biological Process	GO:0061053	somite development	Wnt11	IGI	MGI:MGI:98958	Mouse	PMID:25813538
Biological Process	GO:0072089	stem cell proliferation	Wnt11	IMP		Mouse	PMID:18191119
Biological Process	GO:0060675	ureteric bud morphogenesis	WNT11	IEP		Human	PMID:9757009
Biological Process	GO:0003281	ventricular septum development	Wnt11	IGI	UniProtKB:P22725	Mouse	MGI:MGI:5424267|PMID:22569553
Biological Process	GO:0060412	ventricular septum morphogenesis	Wnt11	IMP	MGI:MGI:2665014	Mouse	PMID:17767158

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern