About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Wnt5a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt5a
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:1902379chemoattractant activity involved in axon guidanceWnt5aIDAMouseMGI:MGI:4866939|PMID:21106844
Molecular FunctionGO:0005125cytokine activityWnt5aIDAMouseMGI:MGI:4820709|PMID:18986540
Molecular FunctionGO:0005109frizzled bindingWNT5AIPIUniProtKB:Q13467HumanPMID:18174455
Molecular FunctionGO:0005109frizzled bindingWnt5aIPIUniProtKB:Q9UP38MouseMGI:MGI:4456962|PMID:10557084
Molecular FunctionGO:0005109frizzled bindingWnt5aIDAMousePMID:19910923
Molecular FunctionGO:0005109frizzled bindingWnt5aIDAMousePMID:10893270
Molecular FunctionGO:0005515protein bindingWNT5AIPIUniProtKB:Q9Y5W5HumanPMID:26342861
Molecular FunctionGO:0005515protein bindingWNT5AIPIUniProtKB:Q5HYA8HumanPMID:34731008
Molecular FunctionGO:0005515protein bindingWnt5aIPIUniProtKB:Q6DID7MouseMGI:MGI:4397730|PMID:19841259
Molecular FunctionGO:0005515protein bindingWnt5aIPIUniProtKB:Q9Y5W5MouseMGI:MGI:5512935|PMID:22986341
Molecular FunctionGO:0005515protein bindingWnt5aIPIUniProtKB:O35082MouseMGI:MGI:3718804|PMID:17690294
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:O88572MousePMID:19056682
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:Q9Z138MousePMID:12839624
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:P97299MousePMID:17462603
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:Q6DID7MousePMID:33324648
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:Q9Z138MousePMID:18606138
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:Q9JJJ7MousePMID:10866835
Molecular FunctionGO:0005515protein bindingWnt5aIPIPR:Q9D1D6MousePMID:18606138
Molecular FunctionGO:0019904protein domain specific bindingWnt5aIPIUniProtKB:Q01887MouseMGI:MGI:3625635|PMID:16723543
Molecular FunctionGO:0005115receptor tyrosine kinase-like orphan receptor bindingWNT5AIPIUniProtKB:Q01973HumanPMID:18287027
Molecular FunctionGO:0005102signaling receptor bindingWnt5aIPIUniProtKB:Q61091MouseMGI:MGI:5706913|PMID:20093360
Molecular FunctionGO:0005102signaling receptor bindingWnt5aIPIPR:Q01887MousePMID:16723543
Cellular ComponentGO:0009986cell surfaceWnt5aIDAMouseMGI:MGI:66576|PMID:8167409
Cellular ComponentGO:0062023collagen-containing extracellular matrixWNT5AHDAHumanPMID:28327460
Cellular ComponentGO:0005737cytoplasmWnt5aIDARatPMID:17194898|RGD:2298807
Cellular ComponentGO:0031012extracellular matrixWnt5aIDAMousePMID:8167409
Cellular ComponentGO:0005615extracellular spaceWNT5AIDAHumanPMID:18703641
Cellular ComponentGO:0005615extracellular spaceWNT5AIDAHumanPMID:19048125
Cellular ComponentGO:0005615extracellular spaceWNT5AIDAHumanPMID:20034610
Cellular ComponentGO:0005615extracellular spaceWnt5aIDARatPMID:16243537|RGD:2317901
Cellular ComponentGO:0098978glutamatergic synapseWNT5AIDAHumanPMID:18986540
Cellular ComponentGO:0098978glutamatergic synapseWNT5AIMPHumanPMID:18986540
Cellular ComponentGO:0098978glutamatergic synapseWNT5AIDAHumanPMID:27402827
Cellular ComponentGO:0098978glutamatergic synapseWNT5AIMPHumanPMID:27402827
Cellular ComponentGO:0098978glutamatergic synapseWnt5aIDAMousePMID:28069946
Cellular ComponentGO:0098978glutamatergic synapseWnt5aIMPMousePMID:28069946
Cellular ComponentGO:0098978glutamatergic synapseWnt5aIDARatPMID:19332546|RGD:155230776
Cellular ComponentGO:0098978glutamatergic synapseWnt5aIMPRatPMID:19332546|RGD:155230776
Cellular ComponentGO:0098978glutamatergic synapseWnt5aEXPRatPMID:26311509|RGD:11353570
Cellular ComponentGO:0098978glutamatergic synapseWnt5aIDARatPMID:26311509|RGD:11353570
Cellular ComponentGO:0098794postsynapseWnt5aIDAMouseMGI:MGI:5829116|PMID:28069946
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseWnt5aIDAMousePMID:28069946
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseWnt5aIMPMousePMID:28069946
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseWnt5aEXPRatPMID:26311509|RGD:11353570
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseWnt5aIDARatPMID:26311509|RGD:11353570
Biological ProcessGO:0090630activation of GTPase activityWnt5aIDAMouseMGI:MGI:3829860|PMID:18953410
Biological ProcessGO:0032148activation of protein kinase B activityWNT5AIDAHumanPMID:20034610
Biological ProcessGO:0008595anterior/posterior axis specification, embryoWnt5aIDAMouseMGI:MGI:4835157|PMID:9054360
Biological ProcessGO:0009952anterior/posterior pattern specificationWnt5aIMPMGI:MGI:1857617MousePMID:19795512
Biological ProcessGO:0009952anterior/posterior pattern specificationWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0003283atrial septum developmentWnt5aIGIUniProtKB:P48615MouseMGI:MGI:5424267|PMID:22569553
Biological ProcessGO:0003401axis elongationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0003401axis elongationWnt5aIMPMGI:MGI:1857617MousePMID:19795512
Biological ProcessGO:0048846axon extension involved in axon guidanceWnt5aIGIMGI:MGI:101766MousePMID:16723543
Biological ProcessGO:0007411axon guidanceWnt5aIDAMouseMGI:MGI:4949958|PMID:21483795
Biological ProcessGO:0007409axonogenesisWnt5aIDAMouseMGI:MGI:5707582|PMID:23517308
Biological ProcessGO:0030509BMP signaling pathwayWnt5aIMPMGI:MGI:1857617MousePMID:18351662
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:5571208|PMID:24681597
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:4835138|PMID:18929644
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIMPMousePMID:18070933
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIMPMousePMID:12952940
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIMPMousePMID:17804636
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIGIMGI:MGI:108520MousePMID:16602827
Biological ProcessGO:0060070canonical Wnt signaling pathwayWnt5aIDAMousePMID:17804636
Biological ProcessGO:0030154cell differentiationWnt5aIEPRatPMID:16780995|RGD:2317900
Biological ProcessGO:0016477cell migrationWnt5aIGIMGI:MGI:2152453MousePMID:17986005
Biological ProcessGO:0016477cell migrationWnt5aIGIMGI:MGI:1861437MousePMID:17986005
Biological ProcessGO:0008283cell population proliferationWnt5aIMPMousePMID:9160667
Biological ProcessGO:0008283cell population proliferationWnt5aIDAMousePMID:9160667
Biological ProcessGO:0071277cellular response to calcium ionWNT5AIEPHumanPMID:18703641
Biological ProcessGO:0071222cellular response to lipopolysaccharideWNT5AIEPHumanPMID:18174455
Biological ProcessGO:0071219cellular response to molecule of bacterial originWnt5aIDAMouseMGI:MGI:4835148|PMID:16601243
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusWNT5AIEPHumanPMID:15040835
Biological ProcessGO:0071346cellular response to type II interferonWNT5AIEPHumanPMID:18174455
Biological ProcessGO:0060067cervix developmentWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0036517chemoattraction of serotonergic neuron axonWnt5aIDAMouseMGI:MGI:4866939|PMID:21106844
Biological ProcessGO:0036518chemorepulsion of dopaminergic neuron axonWnt5aIDAMouseMGI:MGI:4866939|PMID:21106844
Biological ProcessGO:0036518chemorepulsion of dopaminergic neuron axonWnt5aIDAMouseMGI:MGI:5707582|PMID:23517308
Biological ProcessGO:0090103cochlea morphogenesisWnt5aIGIMGI:MGI:2135272MousePMID:17433286
Biological ProcessGO:0090103cochlea morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:17433286
Biological ProcessGO:0060026convergent extensionWnt5aIMPMGI:MGI:1857617MousePMID:17433286
Biological ProcessGO:0060028convergent extension involved in axis elongationWnt5aIMPMGI:MGI:1857617MousePMID:25813538
Biological ProcessGO:0060028convergent extension involved in axis elongationWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0060029convergent extension involved in organogenesisWnt5aIGIMGI:MGI:2135272MousePMID:17433286
Biological ProcessGO:0060029convergent extension involved in organogenesisWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0001816cytokine productionWnt5aIDAMousePMID:23677472
Biological ProcessGO:0007368determination of left/right symmetryWnt5aIMPMGI:MGI:1857617MousePMID:24091014
Biological ProcessGO:0046546development of primary male sexual characteristicsWnt5aIMPMousePMID:19100252
Biological ProcessGO:0048546digestive tract morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19300477
Biological ProcessGO:0071542dopaminergic neuron differentiationWnt5aIDAMouseMGI:MGI:5469218|PMID:23324743
Biological ProcessGO:0071542dopaminergic neuron differentiationWnt5aIGIUniProtKB:P04426MouseMGI:MGI:5469218|PMID:23324743
Biological ProcessGO:0071542dopaminergic neuron differentiationWnt5aIMPMGI:MGI:1857617MousePMID:18953410
Biological ProcessGO:0071542dopaminergic neuron differentiationWnt5aIGIMGI:MGI:97845MousePMID:18953410
Biological ProcessGO:0009790embryo developmentWnt5aIMPMGI:MGI:1857617MousePMID:10021340
Biological ProcessGO:0042733embryonic digit morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19795512
Biological ProcessGO:0030326embryonic limb morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:10021340
Biological ProcessGO:0048706embryonic skeletal system developmentWNT5AIMPHumanPMID:19918918
Biological ProcessGO:0010631epithelial cell migrationWnt5aIMPMGI:MGI:1857617MousePMID:16246260
Biological ProcessGO:0010631epithelial cell migrationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0050673epithelial cell proliferationWnt5aIDAMousePMID:17898001
Biological ProcessGO:0050673epithelial cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:17898001
Biological ProcessGO:0050673epithelial cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0060750epithelial cell proliferation involved in mammary gland duct elongationWnt5aIDAMousePMID:17898001
Biological ProcessGO:0001837epithelial to mesenchymal transitionWNT5AIEPHumanPMID:12841867
Biological ProcessGO:0045198establishment of epithelial cell apical/basal polarityWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0001736establishment of planar polarityWnt5aIMPMGI:MGI:1857617MousePMID:18953410
Biological ProcessGO:0044849estrous cycleWnt5aIEPRatPMID:20126574|RGD:2326233
Biological ProcessGO:0060324face developmentWNT5AIMPHumanPMID:19918918
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayWnt5aIMPMGI:MGI:1857617MousePMID:18351662
Biological ProcessGO:0048806genitalia developmentWNT5AIMPHumanPMID:19918918
Biological ProcessGO:0001947heart loopingWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0071425hematopoietic stem cell proliferationWNT5AIDAHumanPMID:9787155
Biological ProcessGO:0071425hematopoietic stem cell proliferationWnt5aIMPMousePMID:9160667
Biological ProcessGO:0071425hematopoietic stem cell proliferationWnt5aIDAMousePMID:9160667
Biological ProcessGO:0007442hindgut morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:18804104
Biological ProcessGO:0048850hypophysis morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:15037319
Biological ProcessGO:0042472inner ear morphogenesisWnt5aIMPMousePMID:18991062
Biological ProcessGO:0042472inner ear morphogenesisWnt5aIDAMousePMID:18991062
Biological ProcessGO:0007254JNK cascadeWnt5aIDAMousePMID:12839624
Biological ProcessGO:0030216keratinocyte differentiationWNT5AIEPHumanPMID:19399181
Biological ProcessGO:0001822kidney developmentWnt5aIMPMGI:MGI:5646613MousePMID:27002738
Biological ProcessGO:0060599lateral sprouting involved in mammary gland duct morphogenesisWnt5aIDAMousePMID:17898001
Biological ProcessGO:0035108limb morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19795512
Biological ProcessGO:0048286lung alveolus developmentWnt5aIEPRatPMID:17911382|RGD:2304247
Biological ProcessGO:0030324lung developmentWnt5aIMPMGI:MGI:1857617MousePMID:12142021
Biological ProcessGO:0008584male gonad developmentWNT5AIEPHumanPMID:17848411
Biological ProcessGO:0008584male gonad developmentWnt5aIMPMousePMID:19100252
Biological ProcessGO:0008584male gonad developmentWnt5aIMPMGI:MGI:1857617MousePMID:18804104
Biological ProcessGO:0060744mammary gland branching involved in thelarcheWnt5aIDAMousePMID:17898001
Biological ProcessGO:0140013meiotic nuclear divisionWnt5aIGIMGI:MGI:98957MousePMID:20106871
Biological ProcessGO:0097325melanocyte proliferationWnt5aIDAMouseMGI:MGI:5619434|PMID:23569434
Biological ProcessGO:0010463mesenchymal cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0060638mesenchymal-epithelial cell signalingWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0060809mesodermal to mesenchymal transition involved in gastrulationWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0030901midbrain developmentWnt5aIGIUniProtKB:P04426MouseMGI:MGI:5469218|PMID:23324743
Biological ProcessGO:0030901midbrain developmentWnt5aIDAMouseMGI:MGI:2679774|PMID:14557550
Biological ProcessGO:1904948midbrain dopaminergic neuron differentiationWnt5aIMPMouseMGI:MGI:3829860|PMID:18953410
Biological ProcessGO:1904948midbrain dopaminergic neuron differentiationWnt5aIGIUniProtKB:P04426MouseMGI:MGI:5469218|PMID:23324743
Biological ProcessGO:1904948midbrain dopaminergic neuron differentiationWnt5aIDAMouseMGI:MGI:5700308|PMID:15748172
Biological ProcessGO:1904948midbrain dopaminergic neuron differentiationWnt5aIDAMouseMGI:MGI:2679774|PMID:14557550
Biological ProcessGO:0007494midgut developmentWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0050804modulation of chemical synaptic transmissionWnt5aEXPRatPMID:26311509|RGD:11353570
Biological ProcessGO:0050804modulation of chemical synaptic transmissionWnt5aIDARatPMID:26311509|RGD:11353570
Biological ProcessGO:0002009morphogenesis of an epitheliumWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0050919negative chemotaxisWnt5aIGIMGI:MGI:101766MousePMID:16723543
Biological ProcessGO:0043066negative regulation of apoptotic processWNT5AIDAHumanPMID:19251946
Biological ProcessGO:0048843negative regulation of axon extension involved in axon guidanceWnt5aIGIMGI:MGI:101766MousePMID:16723543
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayWnt5aIMPMGI:MGI:1857617MousePMID:18351662
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWNT5AIGIUniProtKB:O43255HumanPMID:12952940
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWNT5AIGIUniProtKB:P25054HumanPMID:12952940
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:4820709|PMID:18986540
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIGIUniProtKB:P27467MouseMGI:MGI:3707948|PMID:17244647
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:3707948|PMID:17244647
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:5619434|PMID:23569434
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIGIMGI:MGI:1888513MousePMID:19910923
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIGIMGI:MGI:98956MousePMID:16602827
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIMPMousePMID:18070933
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIMPMousePMID:12952940
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIGIMGI:MGI:98956MousePMID:19910923
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayWnt5aIGIMGI:MGI:1347521MousePMID:16602827
Biological ProcessGO:1904934negative regulation of cell proliferation in midbrainWnt5aIMPMouseMGI:MGI:3829860|PMID:18953410
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionWNT5AIDAHumanPMID:19277043
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationWnt5aIDAMousePMID:17898001
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:17898001
Biological ProcessGO:0045599negative regulation of fat cell differentiationWNT5AIMPHumanPMID:20032469
Biological ProcessGO:0040037negative regulation of fibroblast growth factor receptor signaling pathwayWnt5aIMPMGI:MGI:1857617MousePMID:18351662
Biological ProcessGO:0048022negative regulation of melanin biosynthetic processWnt5aIDAMouseMGI:MGI:5619434|PMID:23569434
Biological ProcessGO:0072201negative regulation of mesenchymal cell proliferationWNT5AIDAHumanPMID:19878652
Biological ProcessGO:0060686negative regulation of prostatic bud formationWnt5aIMPMGI:MGI:1857617MousePMID:18804104
Biological ProcessGO:0051964negative regulation of synapse assemblyWnt5aIDAMouseMGI:MGI:4820709|PMID:18986540
Biological ProcessGO:0001843neural tube closureWnt5aIGIMGI:MGI:2135272MousePMID:17433286
Biological ProcessGO:0001843neural tube closureWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0021915neural tube developmentWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0022008neurogenesisWnt5aIDAMouseMGI:MGI:2679774|PMID:14557550
Biological ProcessGO:0030182neuron differentiationWnt5aIEPRatPMID:16909041|RGD:2317898
Biological ProcessGO:0048812neuron projection morphogenesisWnt5aIDAMouseMGI:MGI:4949958|PMID:21483795
Biological ProcessGO:0035567non-canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:4949958|PMID:21483795
Biological ProcessGO:0035567non-canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:5700308|PMID:15748172
Biological ProcessGO:0035567non-canonical Wnt signaling pathwayWnt5aIDAMousePMID:23677472
Biological ProcessGO:0038031non-canonical Wnt signaling pathway via JNK cascadeWnt5aIMPMouseMGI:MGI:4820702|PMID:20032469
Biological ProcessGO:0048570notochord morphogenesisWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0021891olfactory bulb interneuron developmentWnt5aIMPMouseMGI:MGI:5285122|PMID:21539518
Biological ProcessGO:0048341paraxial mesoderm formationWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0003344pericardium morphogenesisWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0003402planar cell polarity pathway involved in axis elongationWnt5aIMPMGI:MGI:1857617MousePMID:25813538
Biological ProcessGO:0003402planar cell polarity pathway involved in axis elongationWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:1904938planar cell polarity pathway involved in axon guidanceWnt5aIDAMouseMGI:MGI:5707582|PMID:23517308
Biological ProcessGO:1904938planar cell polarity pathway involved in axon guidanceWnt5aIMPMouseMGI:MGI:4866939|PMID:21106844
Biological ProcessGO:0061350planar cell polarity pathway involved in cardiac muscle tissue morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0061349planar cell polarity pathway involved in cardiac right atrium morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0060775planar cell polarity pathway involved in gastrula mediolateral intercalationWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0090179planar cell polarity pathway involved in neural tube closureWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0061347planar cell polarity pathway involved in outflow tract morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0061354planar cell polarity pathway involved in pericardium morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0061348planar cell polarity pathway involved in ventricular septum morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19056682
Biological ProcessGO:0045766positive regulation of angiogenesisWNT5AIMPHumanPMID:17035633
Biological ProcessGO:0061036positive regulation of cartilage developmentWnt5aIDAMousePMID:18991062
Biological ProcessGO:0061036positive regulation of cartilage developmentWnt5aIMPMousePMID:18991062
Biological ProcessGO:0022409positive regulation of cell-cell adhesionWnt5aIMPRatPMID:15327998|RGD:2317902
Biological ProcessGO:2000049positive regulation of cell-cell adhesion mediated by cadherinWnt5aIDAMousePMID:10893270
Biological ProcessGO:0032722positive regulation of chemokine productionWNT5AIMPHumanPMID:19520808
Biological ProcessGO:0001819positive regulation of cytokine productionWnt5aIDAMousePMID:23677472
Biological ProcessGO:0002720positive regulation of cytokine production involved in immune responseWNT5AIMPHumanPMID:18174455
Biological ProcessGO:1903861positive regulation of dendrite extensionWnt5aIMPRatPMID:25424568|RGD:11060597
Biological ProcessGO:0050775positive regulation of dendrite morphogenesisWnt5aIMPRatPMID:25424568|RGD:11060597
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionWNT5AIMPHumanPMID:19847889
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionWnt5aIDAMouseMGI:MGI:4835138|PMID:18929644
Biological ProcessGO:0045807positive regulation of endocytosisWnt5aIDAMousePMID:24305805
Biological ProcessGO:0010595positive regulation of endothelial cell migrationWNT5AIMPHumanPMID:17035633
Biological ProcessGO:0010595positive regulation of endothelial cell migrationWNT5AIMPHumanPMID:17986384
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationWNT5AIMPHumanPMID:17986384
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0048146positive regulation of fibroblast proliferationWNT5AIDAHumanPMID:19251946
Biological ProcessGO:0010628positive regulation of gene expressionWnt5aIMPMouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0043547positive regulation of GTPase activityWnt5aIDAMouseMGI:MGI:5466648|PMID:23109420
Biological ProcessGO:0090082positive regulation of heart induction by negative regulation of canonical Wnt signaling pathwayWnt5aIGIUniProtKB:P48615MouseMGI:MGI:5424267|PMID:22569553
Biological ProcessGO:1902035positive regulation of hematopoietic stem cell proliferationWnt5aIMPMousePMID:9160667
Biological ProcessGO:1902035positive regulation of hematopoietic stem cell proliferationWnt5aIDAMousePMID:9160667
Biological ProcessGO:0050729positive regulation of inflammatory responseWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionWnt5aIDAMouseMGI:MGI:5009385|PMID:18174455
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionWnt5aIGIComplexPortal:CPX-1134,UniProtKB:Q9EQD0MouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionWnt5aIMPMouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0032755positive regulation of interleukin-6 productionWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0032755positive regulation of interleukin-6 productionWnt5aIDAMouseMGI:MGI:5009385|PMID:18174455
Biological ProcessGO:0032757positive regulation of interleukin-8 productionWnt5aIDAMouseMGI:MGI:5009385|PMID:18174455
Biological ProcessGO:0046330positive regulation of JNK cascadeWnt5aIMPMouseMGI:MGI:4820702|PMID:20032469
Biological ProcessGO:0043507positive regulation of JUN kinase activityWNT5AIMPHumanPMID:20032469
Biological ProcessGO:0043507positive regulation of JUN kinase activityWNT5AIDAHumanPMID:20034610
Biological ProcessGO:0043507positive regulation of JUN kinase activityWnt5aIMPMGI:MGI:1857617MousePMID:19300477
Biological ProcessGO:0043507positive regulation of JUN kinase activityWnt5aIDAMousePMID:19300477
Biological ProcessGO:0043032positive regulation of macrophage activationWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0060907positive regulation of macrophage cytokine productionWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0045836positive regulation of meiotic nuclear divisionWnt5aIGIMGI:MGI:98957MousePMID:20106871
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:1901216positive regulation of neuron deathWnt5aIDAMouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0150012positive regulation of neuron projection arborizationWnt5aIGIUniProtKB:Q9QXQ7MouseMGI:MGI:6114830|PMID:25424568
Biological ProcessGO:0150012positive regulation of neuron projection arborizationWnt5aIGIUniProtKB:P22725RatPMID:25424568|RGD:11060597
Biological ProcessGO:0010976positive regulation of neuron projection developmentWnt5aIDAMouseMGI:MGI:5285122|PMID:21539518
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityWNT5AIDAHumanPMID:18287027
Biological ProcessGO:2000052positive regulation of non-canonical Wnt signaling pathwayWnt5aIDAMouseMGI:MGI:5619434|PMID:23569434
Biological ProcessGO:0045778positive regulation of ossificationWNT5AIMPHumanPMID:20032469
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationWnt5aIGIMGI:MGI:2152453MousePMID:17986005
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationWnt5aIGIMGI:MGI:1861437MousePMID:17986005
Biological ProcessGO:0010800positive regulation of peptidyl-threonine phosphorylationWnt5aIGIMGI:MGI:1861437MousePMID:17986005
Biological ProcessGO:0010800positive regulation of peptidyl-threonine phosphorylationWnt5aIGIMGI:MGI:2152453MousePMID:17986005
Biological ProcessGO:0032092positive regulation of protein bindingWnt5aIDAMouseMGI:MGI:5466648|PMID:23109420
Biological ProcessGO:0045732positive regulation of protein catabolic processWNT5AIGIUniProtKB:O43255HumanPMID:12952940
Biological ProcessGO:0045732positive regulation of protein catabolic processWNT5AIGIUniProtKB:P25054HumanPMID:12952940
Biological ProcessGO:0045860positive regulation of protein kinase activityWnt5aIDAMouseMGI:MGI:3707948|PMID:17244647
Biological ProcessGO:1900020positive regulation of protein kinase C activityWNT5AIMPHumanPMID:12086864
Biological ProcessGO:0090037positive regulation of protein kinase C signalingWNT5AIMPHumanPMID:19099253
Biological ProcessGO:0001934positive regulation of protein phosphorylationWnt5aIDAMouseMGI:MGI:3707948|PMID:17244647
Biological ProcessGO:0001934positive regulation of protein phosphorylationWnt5aIDAMouseMGI:MGI:4949958|PMID:21483795
Biological ProcessGO:0001934positive regulation of protein phosphorylationWnt5aIDAMouseMGI:MGI:5700308|PMID:15748172
Biological ProcessGO:0001934positive regulation of protein phosphorylationWnt5aIDAMousePMID:15143170
Biological ProcessGO:0060760positive regulation of response to cytokine stimulusWNT5AIDAHumanPMID:19399181
Biological ProcessGO:2000648positive regulation of stem cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0010820positive regulation of T cell chemotaxisWNT5AIMPHumanPMID:19520808
Biological ProcessGO:0070245positive regulation of thymocyte apoptotic processWnt5aIMPMousePMID:18070933
Biological ProcessGO:0051885positive regulation of timing of anagenWnt5aIDAMouseMGI:MGI:5571208|PMID:24681597
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIWNT5AIMPHumanPMID:18174455
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionWnt5aIGIComplexPortal:CPX-1134,UniProtKB:Q9EQD0MouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionWnt5aIMPMouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0060340positive regulation of type I interferon-mediated signaling pathwayWNT5AIDAHumanPMID:19399181
Biological ProcessGO:0032729positive regulation of type II interferon productionWnt5aIMPMouseMGI:MGI:4835148|PMID:16601243
Biological ProcessGO:0036342post-anal tail morphogenesisWnt5aIMPMGI:MGI:1857617MousePMID:19795512
Biological ProcessGO:0036342post-anal tail morphogenesisWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0099170postsynaptic modulation of chemical synaptic transmissionWnt5aIDAMousePMID:28069946
Biological ProcessGO:0099170postsynaptic modulation of chemical synaptic transmissionWnt5aIMPMousePMID:28069946
Biological ProcessGO:0003138primary heart field specificationWnt5aIGIUniProtKB:P48615MouseMGI:MGI:5424267|PMID:22569553
Biological ProcessGO:0090009primitive streak formationWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0048793pronephros developmentwnt5aIMPZFIN:ZDB-MRPHLNO-151028-2ZfishPMID:25412793
Biological ProcessGO:0048793pronephros developmentwnt5aIMPZFIN:ZDB-MRPHLNO-151028-1ZfishPMID:25412793
Biological ProcessGO:0030850prostate gland developmentWnt5aIEPRatPMID:19389372|RGD:2317894
Biological ProcessGO:0008104protein localizationWNT5AIDAHumanPMID:19177143
Biological ProcessGO:0008104protein localizationWnt5aIMPMGI:MGI:1857617MousePMID:17433286
Biological ProcessGO:0006468protein phosphorylationWnt5aIGIMGI:MGI:98725MousePMID:17898001
Biological ProcessGO:0060762regulation of branching involved in mammary gland duct morphogenesisWnt5aIGIMGI:MGI:98725MousePMID:17898001
Biological ProcessGO:0060762regulation of branching involved in mammary gland duct morphogenesisWnt5aIDAMousePMID:17898001
Biological ProcessGO:0060762regulation of branching involved in mammary gland duct morphogenesisWnt5aIGIMGI:MGI:96079MousePMID:17898001
Biological ProcessGO:0043122regulation of I-kappaB kinase/NF-kappaB signalingWnt5aIMPMouseMGI:MGI:5291547|PMID:21857966
Biological ProcessGO:0099175regulation of postsynapse organizationWNT5AIDAHumanPMID:27402827
Biological ProcessGO:0099175regulation of postsynapse organizationWNT5AIMPHumanPMID:27402827
Biological ProcessGO:0099566regulation of postsynaptic cytosolic calcium ion concentrationWNT5AIDAHumanPMID:27402827
Biological ProcessGO:0099566regulation of postsynaptic cytosolic calcium ion concentrationWNT5AIMPHumanPMID:27402827
Biological ProcessGO:0099150regulation of postsynaptic specialization assemblyWnt5aIDARatPMID:19332546|RGD:155230776
Biological ProcessGO:0099150regulation of postsynaptic specialization assemblyWnt5aIEPRatPMID:19332546|RGD:155230776
Biological ProcessGO:0099150regulation of postsynaptic specialization assemblyWnt5aIMPRatPMID:19332546|RGD:155230776
Biological ProcessGO:0032880regulation of protein localizationWnt5aIDAMouseMGI:MGI:3707948|PMID:17244647
Biological ProcessGO:0032880regulation of protein localizationWnt5aIDAMousePMID:24305805
Biological ProcessGO:0050807regulation of synapse organizationWNT5AIDAHumanPMID:18986540
Biological ProcessGO:0050807regulation of synapse organizationWNT5AIMPHumanPMID:18986540
Biological ProcessGO:0150045regulation of synaptic signaling by nitric oxideWnt5aEXPRatPMID:26311509|RGD:11353570
Biological ProcessGO:0150045regulation of synaptic signaling by nitric oxideWnt5aIDARatPMID:26311509|RGD:11353570
Biological ProcessGO:0032355response to estradiolWnt5aIEPRatPMID:16551644|RGD:2289005
Biological ProcessGO:0051384response to glucocorticoidWnt5aIEPRatPMID:17911382|RGD:2304247
Biological ProcessGO:0055093response to hyperoxiaWnt5aIEPRatPMID:17911382|RGD:2304247
Biological ProcessGO:0014070response to organic cyclic compoundWnt5aIEPRatPMID:20006014|RGD:2317892
Biological ProcessGO:0010033response to organic substanceWNT5AIEPHumanPMID:17486081
Biological ProcessGO:0010033response to organic substanceWnt5aIEPRatPMID:19931241|RGD:2317893
Biological ProcessGO:1905235response to quercetinWnt5aIEPRatPMID:28032729|RGD:150530464
Biological ProcessGO:0033574response to testosteroneWnt5aIEPRatPMID:17218409|RGD:2314760
Biological ProcessGO:0003139secondary heart field specificationWnt5aIGIUniProtKB:P48615MouseMGI:MGI:5424267|PMID:22569553
Biological ProcessGO:0062009secondary palate developmentWNT5AIMPHumanPMID:18413325
Biological ProcessGO:0061053somite developmentWnt5aIGIMGI:MGI:101948MousePMID:25813538
Biological ProcessGO:0001756somitogenesisWnt5aIGIMGI:MGI:1298218MousePMID:19795512
Biological ProcessGO:0072089stem cell proliferationWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0070242thymocyte apoptotic processWnt5aIMPMousePMID:18070933
Biological ProcessGO:0060606tube closureWnt5aIMPMGI:MGI:1857617MousePMID:19100728
Biological ProcessGO:0003323type B pancreatic cell developmentWnt5aIMPMGI:MGI:1857617MousePMID:16246260
Biological ProcessGO:0060157urinary bladder developmentWnt5aIMPMGI:MGI:1857617MousePMID:18804104
Biological ProcessGO:0060065uterus developmentWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0060068vagina developmentWnt5aIMPMGI:MGI:1857617MousePMID:15073149
Biological ProcessGO:0003281ventricular septum developmentWnt5aIGIUniProtKB:P48615MouseMGI:MGI:5424267|PMID:22569553
Biological ProcessGO:0016055Wnt signaling pathwayWNT5AIDAHumanPMID:20034610
Biological ProcessGO:0016055Wnt signaling pathwayWnt5aIGIMGI:MGI:108476MousePMID:16115200
Biological ProcessGO:0016055Wnt signaling pathwayWnt5aIGIMGI:MGI:108460MousePMID:16115200
Biological ProcessGO:0016055Wnt signaling pathwayWnt5aIGIMGI:MGI:108571MousePMID:11092808
Biological ProcessGO:0016055Wnt signaling pathwayWnt5aIGIMGI:MGI:108520MousePMID:16115200
Biological ProcessGO:1904953Wnt signaling pathway involved in midbrain dopaminergic neuron differentiationWnt5aIDAMouseMGI:MGI:5707582|PMID:23517308
Biological ProcessGO:0007223Wnt signaling pathway, calcium modulating pathwayWNT5AIMPHumanPMID:17986384
Biological ProcessGO:0007223Wnt signaling pathway, calcium modulating pathwayWnt5aIDAMouseMGI:MGI:5009385|PMID:18174455
Biological ProcessGO:0007223Wnt signaling pathway, calcium modulating pathwayWnt5aIMPMousePMID:18070933
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIMPMGI:MGI:1857617MousePMID:19300477
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIDAMousePMID:19056682
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIGIMGI:MGI:97845MousePMID:18953410
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIMPMGI:MGI:1857617MousePMID:17433286
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIGIMGI:MGI:2135272MousePMID:17433286
Biological ProcessGO:0060071Wnt signaling pathway, planar cell polarity pathwayWnt5aIDARatPMID:15537637|RGD:8554067
Biological ProcessGO:0042060wound healingWNT5AIDAHumanPMID:19878652

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/17/2024
MGI 6.24
The Jackson Laboratory