Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT6
  • Mouse genes Wnt6
  • Rat genes Wnt6
  • Zfish genes wnt6a,wnt6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Wnt6	IPI	UniProtKB:Q9CWT0	Mouse	PMID:10866835
Cellular Component	GO:0009986	cell surface	Wnt6	IDA		Mouse	MGI:MGI:66576|PMID:8167409
Cellular Component	GO:0031012	extracellular matrix	Wnt6	IDA		Mouse	PMID:8167409
Biological Process	GO:0009798	axis specification	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Wnt6	IGI	MGI:MGI:98957	Mouse	PMID:11948913
Biological Process	GO:0060684	epithelial-mesenchymal cell signaling	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0072080	nephron tubule development	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0072079	nephron tubule formation	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	WNT6	IMP		Human	PMID:20113781
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Wnt6	IDA		Mouse	PMID:9356179
Biological Process	GO:0010628	positive regulation of gene expression	WNT6	IMP		Human	PMID:20113781
Biological Process	GO:0010628	positive regulation of gene expression	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0010628	positive regulation of gene expression	Wnt6	IDA		Mouse	PMID:11973284
Biological Process	GO:0070172	positive regulation of tooth mineralization	WNT6	IMP		Human	PMID:20113781
Biological Process	GO:0016055	Wnt signaling pathway	Wnt6	IDA		Mouse	PMID:11948913
Biological Process	GO:0016055	Wnt signaling pathway	Wnt6	IDA		Mouse	PMID:11973284

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern