Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT7A
  • Mouse genes Wnt7a
  • Rat genes Wnt7a
  • Zfish genes wnt7aa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	WNT7A	IDA		Human	PMID:18986540
Molecular Function	GO:0005109	frizzled binding	Wnt7a	IPI	PR:Q61090	Mouse	PMID:19497282
Molecular Function	GO:0005109	frizzled binding	Wnt7a	IPI	RGD:631406	Rat	PMID:18567805|RGD:4107045
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:Q9Y5W5	Human	PMID:22986341
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:Q9Y5W5	Human	PMID:26342861
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:Q9Z0J1	Human	PMID:30026314
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WNT7A	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Wnt7a	IPI	UniProtKB:Q9CWT0	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Wnt7a	IPI	RGD:621075	Rat	PMID:18567805|RGD:4107045
Molecular Function	GO:0048018	receptor ligand activity	WNT7A	IDA		Human	PMID:18986540
Molecular Function	GO:0048018	receptor ligand activity	WNT7A	IDA		Human	PMID:28733458
Molecular Function	GO:0005102	signaling receptor binding	WNT7A	IPI	UniProtKB:Q13467	Human	PMID:12857724
Cellular Component	GO:0009986	cell surface	Wnt7a	IDA		Mouse	MGI:MGI:66576|PMID:8167409
Cellular Component	GO:0031012	extracellular matrix	Wnt7a	IDA		Mouse	PMID:8167409
Cellular Component	GO:0098978	glutamatergic synapse	WNT7A	EXP		Human	PMID:20530549
Cellular Component	GO:0098978	glutamatergic synapse	WNT7A	IDA		Human	PMID:20530549
Cellular Component	GO:0098978	glutamatergic synapse	WNT7A	IMP		Human	PMID:20530549
Cellular Component	GO:0098978	glutamatergic synapse	Wnt7a	IMP		Mouse	PMID:21670302
Cellular Component	GO:0098978	glutamatergic synapse	Wnt7a	IDA		Mouse	PMID:21670302
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Wnt7a	IDA		Mouse	PMID:26400647
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Wnt7a	EXP		Mouse	PMID:26400647
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Wnt7a	IMP		Mouse	PMID:26400647
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Wnt7a	IPI		Mouse	PMID:26400647
Biological Process	GO:0001525	angiogenesis	Wnt7a	IGI	MGI:MGI:98962	Mouse	PMID:19129494
Biological Process	GO:0006915	apoptotic process	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0045167	asymmetric protein localization involved in cell fate determination	Wnt7a	IDA		Mouse	PMID:19497282
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7A	IDA		Human	PMID:12857724
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7A	IDA		Human	PMID:15802269
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7A	IDA		Human	PMID:16805831
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7A	IDA		Human	PMID:18986540
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT7A	IDA		Human	PMID:28733458
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7a	IDA		Mouse	MGI:MGI:4441133|PMID:12937339
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7a	IGI	MGI:MGI:98962	Mouse	PMID:19023080
Biological Process	GO:0060070	canonical Wnt signaling pathway	Wnt7a	IMP		Rat	PMID:18567805|RGD:4107045
Biological Process	GO:0001502	cartilage condensation	WNT7A	IDA		Human	PMID:17202865
Biological Process	GO:0051216	cartilage development	Wnt7a	IDA		Mouse	MGI:MGI:4821073|PMID:16826533
Biological Process	GO:0021846	cell proliferation in forebrain	WNT7A	IDA		Human	PMID:12843296
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	WNT7A	IEP		Human	PMID:15040835
Biological Process	GO:0022009	central nervous system vasculogenesis	Wnt7a	IGI	MGI:MGI:98962	Mouse	PMID:19023080
Biological Process	GO:0021707	cerebellar granule cell differentiation	Wnt7a	IDA		Mouse	PMID:9405095
Biological Process	GO:0002062	chondrocyte differentiation	WNT7A	IDA		Human	PMID:17202865
Biological Process	GO:0060997	dendritic spine morphogenesis	WNT7A	IDA		Human	PMID:21670302
Biological Process	GO:0060997	dendritic spine morphogenesis	Wnt7a	IGI	UniProtKB:Q9WVB9	Mouse	MGI:MGI:5014434|PMID:21670302
Biological Process	GO:0009953	dorsal/ventral pattern formation	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:9362463
Biological Process	GO:0009953	dorsal/ventral pattern formation	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:7885472
Biological Process	GO:0000578	embryonic axis specification	WNT7A	IMP		Human	PMID:16826533
Biological Process	GO:0042733	embryonic digit morphogenesis	WNT7A	IMP		Human	PMID:16826533
Biological Process	GO:0035115	embryonic forelimb morphogenesis	WNT7A	IMP		Human	PMID:16826533
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Wnt7a	IGI	MGI:MGI:95389	Mouse	PMID:9362463
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Wnt7a	IGI	MGI:MGI:1298218	Mouse	PMID:15880584
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	WNT7A	IMP		Human	PMID:16826533
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Wnt7a	IGI	MGI:MGI:1298218	Mouse	PMID:15880584
Biological Process	GO:0030326	embryonic limb morphogenesis	Wnt7a	IGI	MGI:MGI:1329040	Mouse	PMID:15242796
Biological Process	GO:0030326	embryonic limb morphogenesis	Wnt7a	IGI	MGI:MGI:95389	Mouse	PMID:15242796
Biological Process	GO:0060856	establishment of blood-brain barrier	Wnt7a	IGI	MGI:MGI:102570	Mouse	PMID:30478038
Biological Process	GO:0060856	establishment of blood-brain barrier	Wnt7a	IGI	MGI:MGI:108520	Mouse	PMID:30478038
Biological Process	GO:0030010	establishment of cell polarity	Wnt7a	IDA		Mouse	PMID:19497282
Biological Process	GO:0035136	forelimb morphogenesis	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0035137	hindlimb morphogenesis	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0060173	limb development	Wnt7a	IDA		Mouse	MGI:MGI:4821073|PMID:16826533
Biological Process	GO:0043066	negative regulation of apoptotic process	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0050768	negative regulation of neurogenesis	WNT7A	IDA		Human	PMID:12843296
Biological Process	GO:0007269	neurotransmitter secretion	Wnt7a	IGI	MGI:MGI:94941	Mouse	PMID:16818724
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	Wnt7a	IGI	MGI:MGI:108570	Mouse	PMID:19497282
Biological Process	GO:0060066	oviduct development	Wnt7a	IMP		Mouse	MGI:MGI:3777712|PMID:14695376
Biological Process	GO:0008284	positive regulation of cell population proliferation	Wnt7a	IMP		Rat	PMID:18567805|RGD:4107045
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	WNT7A	IDA		Human	PMID:15802269
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Wnt7a	IDA		Mouse	MGI:MGI:4441133|PMID:12937339
Biological Process	GO:0010595	positive regulation of endothelial cell migration	Wnt7a	IDA		Mouse	PMID:19129494
Biological Process	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	WNT7A	IDA		Human	PMID:15802269
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	WNT7A	IDA		Human	PMID:21670302
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Wnt7a	IGI	UniProtKB:Q9WVB9	Mouse	MGI:MGI:5014434|PMID:21670302
Biological Process	GO:1904891	positive regulation of excitatory synapse assembly	WNT7A	IDA		Human	PMID:21670302
Biological Process	GO:0010628	positive regulation of gene expression	Wnt7a	IDA		Mouse	PMID:19129494
Biological Process	GO:0046330	positive regulation of JNK cascade	Wnt7a	IMP		Rat	PMID:18567805|RGD:4107045
Biological Process	GO:0051247	positive regulation of protein metabolic process	WNT7A	IDA		Human	PMID:16805831
Biological Process	GO:0051965	positive regulation of synapse assembly	WNT7A	IDA		Human	PMID:18986540
Biological Process	GO:0051965	positive regulation of synapse assembly	Wnt7a	IDA		Mouse	PMID:9405095
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	WNT7A	IDA		Human	PMID:12857724
Biological Process	GO:0031133	regulation of axon diameter	Wnt7a	IDA		Mouse	PMID:9405095
Biological Process	GO:0050770	regulation of axonogenesis	Wnt7a	IDA		Mouse	PMID:9405095
Biological Process	GO:0042127	regulation of cell population proliferation	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0099175	regulation of postsynapse organization	Wnt7a	IDA		Mouse	PMID:21670302
Biological Process	GO:0099175	regulation of postsynapse organization	Wnt7a	IMP		Mouse	PMID:21670302
Biological Process	GO:1905606	regulation of presynapse assembly	WNT7A	EXP		Human	PMID:20530549
Biological Process	GO:1905606	regulation of presynapse assembly	WNT7A	IDA		Human	PMID:20530549
Biological Process	GO:1905606	regulation of presynapse assembly	WNT7A	IMP		Human	PMID:20530549
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Wnt7a	IPI		Mouse	PMID:26400647
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Wnt7a	EXP		Mouse	PMID:26400647
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Wnt7a	IDA		Mouse	PMID:26400647
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Wnt7a	IMP		Mouse	PMID:26400647
Biological Process	GO:0048608	reproductive structure development	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0032355	response to estradiol	Wnt7a	IEP		Rat	PMID:16551644|RGD:2289005
Biological Process	GO:0043627	response to estrogen	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0062009	secondary palate development	WNT7A	IMP		Human	PMID:18413325
Biological Process	GO:0014719	skeletal muscle satellite cell activation	Wnt7a	IDA		Mouse	PMID:19497282
Biological Process	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	Wnt7a	IDA		Mouse	PMID:19497282
Biological Process	GO:0048705	skeletal system morphogenesis	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0043589	skin morphogenesis	Wnt7a	IMP	MGI:MGI:1857009	Mouse	MGI:MGI:48652
Biological Process	GO:0048103	somatic stem cell division	Wnt7a	IDA		Mouse	PMID:19497282
Biological Process	GO:0035019	somatic stem cell population maintenance	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:19497282
Biological Process	GO:0048864	stem cell development	WNT7A	IDA		Human	PMID:12843296
Biological Process	GO:0007416	synapse assembly	Wnt7a	IDA		Mouse	PMID:9405095
Biological Process	GO:0050808	synapse organization	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:16818724
Biological Process	GO:0050808	synapse organization	Wnt7a	IGI	MGI:MGI:94941	Mouse	PMID:16818724
Biological Process	GO:0060065	uterus development	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15070830
Biological Process	GO:0060065	uterus development	Wnt7a	IMP	MGI:MGI:1857704	Mouse	PMID:15073149
Biological Process	GO:0061038	uterus morphogenesis	Wnt7a	IMP		Mouse	MGI:MGI:3777712|PMID:14695376
Biological Process	GO:0016055	Wnt signaling pathway	Wnt7a	IGI	UniProtKB:Q9WVB9	Mouse	MGI:MGI:5014434|PMID:21670302
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	WNT7A	IDA		Human	PMID:15802269
Biological Process	GO:0042060	wound healing	Wnt7a	IEP		Rat	PMID:17001188|RGD:2317897
Biological Process	GO:0035313	wound healing, spreading of epidermal cells	WNT7A	IDA		Human	PMID:15802269

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern