Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WNT8A
  • Mouse genes Wnt8a
  • Rat genes Wnt8a
  • Zfish genes wnt8a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wnt8a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Wnt8a	IPI	UniProtKB:O19116	Mouse	PMID:10640709
Molecular Function	GO:0048018	receptor ligand activity	WNT8A	IDA		Human	PMID:28733458
Cellular Component	GO:0097189	apoptotic body	wnt8a	IDA		Zfish	PMID:30837472
Cellular Component	GO:0009986	cell surface	wnt8a	IDA		Zfish	PMID:30837472
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-060724-3	Zfish	PMID:16547521
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP		Zfish	PMID:15366022
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IDA		Zfish	PMID:19471023
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP		Zfish	PMID:14757644
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP	ZFIN:ZDB-GENO-180919-13	Zfish	PMID:29208373
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15772132
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IDA		Zfish	PMID:19572019
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP		Zfish	PMID:11566861
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:11703928
Biological Process	GO:0009952	anterior/posterior pattern specification	wnt8a	IMP	ZFIN:ZDB-GENO-180919-10	Zfish	PMID:29208373
Biological Process	GO:0035284	brain segmentation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:15703279
Biological Process	GO:0035284	brain segmentation	wnt8a	IMP	ZFIN:ZDB-GENO-020130-1	Zfish	PMID:15703279
Biological Process	GO:0060070	canonical Wnt signaling pathway	WNT8A	IDA		Human	PMID:28733458
Biological Process	GO:0060070	canonical Wnt signaling pathway	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:20685732
Biological Process	GO:0060070	canonical Wnt signaling pathway	wnt8a	IMP		Zfish	PMID:23987510
Biological Process	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	WNT8A	IEP		Human	PMID:20559569
Biological Process	GO:0060823	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:22100263
Biological Process	GO:0045165	cell fate commitment	wnt8a	IGI	ZFIN:ZDB-GENE-980528-2059	Zfish	PMID:12879074
Biological Process	GO:0045165	cell fate commitment	wnt8a	IDA		Zfish	PMID:14973296
Biological Process	GO:0042074	cell migration involved in gastrulation	wnt8a	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0000902	cell morphogenesis	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0039015	cell proliferation involved in pronephros development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:28359809
Biological Process	GO:0007417	central nervous system development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:11566861
Biological Process	GO:0048263	determination of dorsal identity	wnt8a	IMP		Zfish	PMID:21911385
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP		Zfish	PMID:9753682
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-110401-1	Zfish	PMID:21282610
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:21282610
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP	ZFIN:ZDB-GENO-180919-10	Zfish	PMID:29208373
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP	ZFIN:ZDB-GENO-020130-1	Zfish	PMID:15269175
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP	ZFIN:ZDB-GENO-180919-13	Zfish	PMID:29208373
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15772132
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IGI	ZFIN:ZDB-GENE-010108-1,ZFIN:ZDB-GENE-010108-2	Zfish	PMID:15269175
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IGI	ZFIN:ZDB-GENE-000328-4	Zfish	PMID:9753682
Biological Process	GO:0009953	dorsal/ventral pattern formation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:18762581
Biological Process	GO:0007398	ectoderm development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:11703928
Biological Process	GO:0000578	embryonic axis specification	wnt8a	IMP		Zfish	PMID:25371059|ZFIN:ZDB-PUB-141106-9
Biological Process	GO:0007492	endoderm development	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0007492	endoderm development	wnt8a	IMP	ZFIN:ZDB-GENO-090304-8	Zfish	PMID:18585699
Biological Process	GO:0048561	establishment of animal organ orientation	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0001654	eye development	wnt8a	IGI	ZFIN:ZDB-GENE-040310-5	Zfish	PMID:16854974
Biological Process	GO:0001654	eye development	wnt8a	IGI	ZFIN:ZDB-GENE-011108-2	Zfish	PMID:16854974
Biological Process	GO:0001654	eye development	wnt8a	IDA		Zfish	PMID:16854974
Biological Process	GO:0030902	hindbrain development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:15797017
Biological Process	GO:0030902	hindbrain development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:19341460
Biological Process	GO:0030902	hindbrain development	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2	Zfish	PMID:15797017
Biological Process	GO:0007498	mesoderm development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:11703928
Biological Process	GO:0007498	mesoderm development	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15772132
Biological Process	GO:0001707	mesoderm formation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0001707	mesoderm formation	wnt8a	IMP		Zfish	PMID:15240553
Biological Process	GO:0001710	mesodermal cell fate commitment	wnt8a	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	wnt8a	IGI	ZFIN:ZDB-GENE-050522-216	Zfish	PMID:23533179
Biological Process	GO:0014036	neural crest cell fate specification	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:20685732
Biological Process	GO:0021999	neural plate anterior/posterior regionalization	wnt8a	IGI	ZFIN:ZDB-GENE-030131-3200,ZFIN:ZDB-GENE-990415-198	Zfish	PMID:26041917
Biological Process	GO:0021999	neural plate anterior/posterior regionalization	wnt8a	IGI	ZFIN:ZDB-GENE-030131-3200	Zfish	PMID:26041917
Biological Process	GO:0060896	neural plate pattern specification	wnt8a	IDA		Zfish	PMID:19580801
Biological Process	GO:0030903	notochord development	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15772132
Biological Process	GO:0030903	notochord development	wnt8a	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0030903	notochord development	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0009949	polarity specification of anterior/posterior axis	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0010085	polarity specification of proximal/distal axis	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	wnt8a	IMP		Zfish	PMID:25371059|ZFIN:ZDB-PUB-141106-9
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	wnt8a	IMP	ZFIN:ZDB-GENO-020130-1	Zfish	PMID:14757644
Biological Process	GO:0010628	positive regulation of gene expression	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:21282610
Biological Process	GO:0010628	positive regulation of gene expression	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-110401-1	Zfish	PMID:21282610
Biological Process	GO:0036342	post-anal tail morphogenesis	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15772132
Biological Process	GO:0036342	post-anal tail morphogenesis	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:15772132
Biological Process	GO:0003002	regionalization	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:2000742	regulation of anterior head development	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-140124-6	Zfish	PMID:24038582
Biological Process	GO:0042127	regulation of cell population proliferation	wnt8a	IMP		Zfish	PMID:30837472
Biological Process	GO:0032880	regulation of protein localization	Wnt8a	IMP		Mouse	PMID:16256739
Biological Process	GO:0062009	secondary palate development	WNT8A	IMP		Human	PMID:18413325
Biological Process	GO:0001756	somitogenesis	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-050509-2	Zfish	PMID:15708563
Biological Process	GO:0001756	somitogenesis	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:15772132
Biological Process	GO:0060061	Spemann organizer formation	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:23987510
Biological Process	GO:0060061	Spemann organizer formation	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:0021512	spinal cord anterior/posterior patterning	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12	Zfish	PMID:11566861
Biological Process	GO:0016055	Wnt signaling pathway	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-070822-2	Zfish	PMID:17510365
Biological Process	GO:0016055	Wnt signaling pathway	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-070822-1	Zfish	PMID:17510365
Biological Process	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification	wnt8a	IMP		Zfish	PMID:18762581|ZFIN:ZDB-PUB-080908-2
Biological Process	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification	wnt8a	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification	wnt8a	IMP	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13	Zfish	PMID:22100263

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern