Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WWP2
  • Mouse genes Wwp2
  • Rat genes Wwp2
  • Zfish genes wwp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wwp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9Y3C5	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9NR12	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P84022	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15796	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P49281	Human	PMID:18776082
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P49281-1	Human	PMID:18776082
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q01860	Human	PMID:19274063
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15303	Human	PMID:20858735
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O15105	Human	PMID:21258410
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P84022	Human	PMID:21258410
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15796	Human	PMID:21258410
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O43516	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUJ2	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUZ4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9H469	Human	PMID:21572392
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P78563	Human	PMID:21847096
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N5I2	Human	PMID:22315426
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N5I2	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q96B67	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:A5D8V6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O43516	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q3B8N2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q5TAL4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N8A2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8WU02	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q96D16	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUJ2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BVN2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9NR12	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P84022	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:A0A0S2Z5X4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15884	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N5I2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15884	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q3B8N2	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUJ2	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9NR12	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15884	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q3B8N2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N8A2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUJ2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9NR12	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P09234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P14678-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P61964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15599	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q71SY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q7L5A3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q86UU5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8IZ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N5I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8N7B9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8NHY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8TAE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q969T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q96B67	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q96LR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q99954	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUJ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9BUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9HAC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9HBE1-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9Y272	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O14773	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O43464	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O43933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P07339	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P22314	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P48643	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P60891	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q14203-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q14204	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q99732	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9NWW5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:Q15884	Human	PMID:34927784
Molecular Function	GO:0005515	protein binding	WWP2	IPI	UniProtKB:P54259	Human	PMID:9647693
Molecular Function	GO:0005515	protein binding	Wwp2	IPI	PR:Q04887	Mouse	PMID:21427722
Molecular Function	GO:0005515	protein binding	Wwp2	IPI	PR:Q8VCB2	Mouse	PMID:21427722
Molecular Function	GO:0005515	protein binding	Wwp2	IPI	PR:Q8BGW2	Mouse	PMID:31845480
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	WWP2	IPI	UniProtKB:Q01860	Human	PMID:19274063
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Wwp2	IPI	UniProtKB:P20263	Mouse	MGI:MGI:4887340|PMID:15047715
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Wwp2	IGI	MGI:MGI:98371	Mouse	PMID:21427722
Molecular Function	GO:0008134	transcription factor binding	WWP2	IPI	UniProtKB:P11161	Human	PMID:19651900
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	WWP2	IMP		Human	PMID:18776082
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	WWP2	IDA		Human	PMID:19274063
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	WWP2	IDA		Human	PMID:19651900
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	WWP2	IDA		Human	PMID:24105792
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Wwp2	IDA		Mouse	MGI:MGI:4821930|PMID:19997087
Cellular Component	GO:0005737	cytoplasm	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Cellular Component	GO:0070062	extracellular exosome	WWP2	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	WWP2	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	WWP2	IDA		Human	PMID:19274063
Cellular Component	GO:0005634	nucleus	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Cellular Component	GO:0005634	nucleus	Wwp2	IDA		Mouse	PMID:21427722
Biological Process	GO:0006858	extracellular transport	WWP2	IMP		Human	PMID:22315426
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Biological Process	GO:0010629	negative regulation of gene expression	WWP2	IMP		Human	PMID:18776082
Biological Process	GO:0051224	negative regulation of protein transport	WWP2	IMP		Human	PMID:18776082
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	WWP2	IMP		Human	PMID:19274063
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Biological Process	GO:0032410	negative regulation of transporter activity	WWP2	IDA		Human	PMID:18776082
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wwp2	IGI	MGI:MGI:98371	Mouse	PMID:21427722
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Wwp2	IGI	MGI:MGI:1922863	Mouse	PMID:21427722
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	WWP2	IMP		Human	PMID:19274063
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Wwp2	IMP		Mouse	MGI:MGI:4821930|PMID:19997087
Biological Process	GO:0051865	protein autoubiquitination	WWP2	IDA		Human	PMID:24105792
Biological Process	GO:0070534	protein K63-linked ubiquitination	Wwp2	IMP		Mouse	MGI:MGI:4821930|PMID:19997087
Biological Process	GO:0016567	protein ubiquitination	WWP2	IDA		Human	PMID:26280536
Biological Process	GO:0016567	protein ubiquitination	WWP2	IDA		Human	PMID:18776082
Biological Process	GO:0016567	protein ubiquitination	WWP2	IMP		Human	PMID:22315426
Biological Process	GO:0016567	protein ubiquitination	Wwp2	IDA		Mouse	MGI:MGI:4887340|PMID:15047715
Biological Process	GO:0042391	regulation of membrane potential	WWP2	IDA		Human	PMID:17289006
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	WWP2	IDA		Human	PMID:17289006
Biological Process	GO:1901016	regulation of potassium ion transmembrane transporter activity	WWP2	IDA		Human	PMID:17289006
Biological Process	GO:0060021	roof of mouth development	wwp2	IMP	ZFIN:ZDB-MRPHLNO-120518-3	Zfish	PMID:21427722
Biological Process	GO:0006366	transcription by RNA polymerase II	Wwp2	IGI	MGI:MGI:1922863	Mouse	PMID:21427722
Biological Process	GO:0006366	transcription by RNA polymerase II	Wwp2	IGI	MGI:MGI:98371	Mouse	PMID:21427722

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern