Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIRC8,XIAP
  • Mouse genes Xiap
  • Rat genes Xiap
  • Zfish genes xiap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Xiap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	XIAP	IDA		Human	PMID:11257230
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	XIAP	IDA		Human	PMID:11257231
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	XIAP	IDA		Human	PMID:16916640
Molecular Function	GO:0042802	identical protein binding	XIAP	IPI	UniProtKB:P98170	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	XIAP	IPI	UniProtKB:P98170	Human	PMID:19273858
Molecular Function	GO:0042802	identical protein binding	XIAP	IPI	UniProtKB:P98170	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	XIAP	IPI	UniProtKB:P98170	Human	PMID:31515488
Molecular Function	GO:0002020	protease binding	Xiap	IPI	RGD:2275	Rat	PMID:18485100|RGD:2314399
Molecular Function	GO:0002020	protease binding	Xiap	IPI	RGD:61867	Rat	PMID:18485100|RGD:2314399
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28-1	Human	PMID:11140638
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55210	Human	PMID:11257230
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55210	Human	PMID:11257231
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P42574	Human	PMID:11257232
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:11583623
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:11602612
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:11604410
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9JIY5	Human	PMID:11604410
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:11604410
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:11801603
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:11801603
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:11801603
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q15750	Human	PMID:11865055
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:12620238
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q8N668	Human	PMID:14685266
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96FJ2	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96HA8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:16282325
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P0CG48	Human	PMID:17318174
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P46531	Human	PMID:17318174
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P51668	Human	PMID:17318174
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:18022362
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9H2J4	Human	PMID:19012568
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P42574	Human	PMID:19273858
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P60484	Human	PMID:19473982
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P61077	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P61088	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P62837	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q13404	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:19667203
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28-1	Human	PMID:19667203
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O14618	Human	PMID:20154138
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O00165	Human	PMID:20171186
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43236-6	Human	PMID:21185211
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q8IUQ4	Human	PMID:21185211
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:21185211
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O15392	Human	PMID:21536684
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43236	Human	PMID:21695558
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:21695558
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O94966	Human	PMID:21849505
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P57078	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P63000	Human	PMID:22117219
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q04726	Human	PMID:22304967
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NQB0	Human	PMID:22304967
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:22465666
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O14618	Human	PMID:22508683
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9NR28	Human	PMID:23251006
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:23818254
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q15750	Human	PMID:23818254
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9JIQ3:PRO_0000021073	Human	PMID:23818254
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:24698088
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P42574	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q13404	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:A5D8V6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P19447	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P40937	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P61024	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q17RB8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q92851	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9HC98	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q92851-4	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43447	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q15750	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96HA8	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96FJ2	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P42574	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:28642151
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83110-1	Human	PMID:28642151
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43236,UniProtKB:P10415	Human	PMID:29020630
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P40937	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83105	Human	PMID:31036715
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83110	Human	PMID:31260151
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83110-1	Human	PMID:31260151
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83110-2	Human	PMID:31260151
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55210	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:31470122
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83105	Human	PMID:31470122
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P83110	Human	PMID:31470122
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:A5D8V6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P19447	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P40937	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P61024	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q17RB8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96FJ2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9HC98	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9Y2D8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43464	Human	PMID:31617661
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:A0A087WZT3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P40937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P47897	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P55211	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P61024	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q06455-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q17RB8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q8N3J5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96CN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:Q9Y3E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:O43353	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	XIAP	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Xiap	IPI	UniProtKB:P28661	Mouse	MGI:MGI:6268242|PMID:30389919
Molecular Function	GO:0005515	protein binding	Xiap	IPI	UniProtKB:Q9JIY5	Mouse	MGI:MGI:5315367|PMID:11604410
Molecular Function	GO:0005515	protein binding	Xiap	IPI	UniProtKB:Q9QYH6	Mouse	MGI:MGI:3848096|PMID:19268530
Molecular Function	GO:0005515	protein binding	Xiap	IPI	UniProtKB:P53702	Mouse	PMID:16858406
Molecular Function	GO:0005515	protein binding	Xiap	IPI	RGD:1585988	Rat	PMID:18485100|RGD:2314399
Molecular Function	GO:0005515	protein binding	Xiap	IPI	RGD:735204	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0120283	protein serine/threonine kinase binding	XIAP	IPI	UniProtKB:P27448	Human	PMID:11865055
Molecular Function	GO:0097110	scaffold protein binding	Xiap	IPI	RGD:628637	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0061630	ubiquitin protein ligase activity	XIAP	EXP		Human	PMID:22304967
Molecular Function	GO:0061630	ubiquitin protein ligase activity	XIAP	IDA		Human	PMID:36394357
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	XIAP	IDA		Human	PMID:19473982
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	XIAP	IDA		Human	PMID:20154138
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	XIAP	IDA		Human	PMID:21931591
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	XIAP	IDA		Human	PMID:22304967
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	XIAP	IMP		Human	PMID:29020630
Cellular Component	GO:0005737	cytoplasm	XIAP	IDA		Human	PMID:15665297
Cellular Component	GO:0005737	cytoplasm	XIAP	IDA		Human	PMID:22304967
Cellular Component	GO:0005737	cytoplasm	Xiap	IDA		Mouse	PMID:15737931
Cellular Component	GO:0005737	cytoplasm	Xiap	IDA		Rat	PMID:17514421|RGD:2314387
Cellular Component	GO:0005737	cytoplasm	Xiap	IDA		Rat	PMID:18485100|RGD:2314399
Cellular Component	GO:0005829	cytosol	Xiap	IDA		Rat	PMID:17514421|RGD:2314387
Cellular Component	GO:0005829	cytosol	Xiap	IDA		Rat	PMID:18485100|RGD:2314399
Cellular Component	GO:0005634	nucleus	XIAP	IDA		Human	PMID:22304967
Cellular Component	GO:0005634	nucleus	Xiap	IDA		Rat	PMID:17514421|RGD:2314387
Cellular Component	GO:0005634	nucleus	Xiap	IDA		Rat	PMID:18485100|RGD:2314399
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Xiap	IDA		Rat	PMID:17514421|RGD:2314387
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Xiap	IDA		Rat	PMID:18485100|RGD:2314399
Cellular Component	GO:0032991	protein-containing complex	Xiap	IDA		Rat	PMID:19416975|RGD:5491011
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Xiap	IEP		Rat	PMID:16157298|RGD:152025207
Biological Process	GO:0006974	DNA damage response	XIAP	IEP		Human	PMID:18049476
Biological Process	GO:0097340	inhibition of cysteine-type endopeptidase activity	XIAP	IDA		Human	PMID:11865055
Biological Process	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Xiap	IMP		Mouse	PMID:14623868
Biological Process	GO:0043066	negative regulation of apoptotic process	XIAP	IDA		Human	PMID:11257230
Biological Process	GO:0043066	negative regulation of apoptotic process	XIAP	IMP		Human	PMID:18049476
Biological Process	GO:0043066	negative regulation of apoptotic process	XIAP	IMP		Human	PMID:22173242
Biological Process	GO:0043066	negative regulation of apoptotic process	Xiap	IDA		Mouse	PMID:12153481
Biological Process	GO:0043066	negative regulation of apoptotic process	Xiap	IMP		Rat	PMID:17869439|RGD:2314390
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	XIAP	IDA		Human	PMID:11583623
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Xiap	IDA		Mouse	PMID:12153481
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Xiap	IDA		Mouse	PMID:12011074
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Xiap	IDA		Rat	PMID:16336964|RGD:2314393
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Xiap	IMP		Rat	PMID:18485100|RGD:2314399
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	XIAP	IDA		Human	PMID:11865055
Biological Process	GO:0051402	neuron apoptotic process	Xiap	IMP		Mouse	PMID:14623868
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	XIAP	IMP		Human	PMID:22304967
Biological Process	GO:0046330	positive regulation of JNK cascade	XIAP	IDA		Human	PMID:11865055
Biological Process	GO:1902530	positive regulation of protein linear polyubiquitination	XIAP	IDA		Human	PMID:21931591
Biological Process	GO:0031398	positive regulation of protein ubiquitination	XIAP	IDA		Human	PMID:21931591
Biological Process	GO:0032481	positive regulation of type I interferon production	XIAP	IDA		Human	PMID:36394357
Biological Process	GO:0060785	regulation of apoptosis involved in tissue homeostasis	Xiap	IMP		Mouse	MGI:MGI:6268242|PMID:30389919
Biological Process	GO:0042981	regulation of apoptotic process	XIAP	IDA		Human	PMID:11865055

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern