Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes XIRP1
  • Mouse genes Xirp1
  • Rat genes Xirp1
  • Zfish genes xirp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Xirp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	XIRP1	IMP		Human	PMID:15454575
Molecular Function	GO:0005515	protein binding	XIRP1	IPI	UniProtKB:P50552	Human	PMID:16631741
Molecular Function	GO:0005515	protein binding	XIRP1	IPI	UniProtKB:Q14315	Human	PMID:16631741
Molecular Function	GO:0003723	RNA binding	XIRP1	HDA		Human	PMID:22658674
Cellular Component	GO:0005912	adherens junction	Xirp1	IDA		Mouse	PMID:12203715
Cellular Component	GO:0005916	fascia adherens	Xirp1	IDA		Mouse	PMID:10021346
Cellular Component	GO:0005916	fascia adherens	Xirp1	IDA		Mouse	PMID:16708114
Cellular Component	GO:0005925	focal adhesion	XIRP1	IMP		Human	PMID:15454575
Cellular Component	GO:0014704	intercalated disc	Xirp1	IDA		Mouse	PMID:17766470
Cellular Component	GO:0001725	stress fiber	XIRP1	IMP		Human	PMID:15454575
Biological Process	GO:0007015	actin filament organization	XIRP1	IMP		Human	PMID:15454575
Biological Process	GO:0055013	cardiac muscle cell development	Xirp1	IMP	MGI:MGI:3521795	Mouse	PMID:17766470
Biological Process	GO:0021782	glial cell development	xirp1	IMP	ZFIN:ZDB-CRISPR-191008-13,ZFIN:ZDB-CRISPR-191008-14	Zfish	PMID:30924555
Biological Process	GO:0008285	negative regulation of cell population proliferation	Xirp1	IMP		Mouse	PMID:17855775
Biological Process	GO:0032091	negative regulation of protein binding	XIRP1	IMP		Human	PMID:15454575
Biological Process	GO:0007219	Notch signaling pathway	Xirp1	IDA		Mouse	PMID:23117660
Biological Process	GO:0042391	regulation of membrane potential	Xirp1	IMP	MGI:MGI:3521795	Mouse	PMID:17766470
Biological Process	GO:0060041	retina development in camera-type eye	xirp1	IMP	ZFIN:ZDB-CRISPR-191008-13,ZFIN:ZDB-CRISPR-191008-14	Zfish	PMID:30924555
Biological Process	GO:0045214	sarcomere organization	Xirp1	IMP	MGI:MGI:3521795	Mouse	PMID:17766470

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern