Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes XPA
  • Mouse genes Xpa
  • Rat genes Xpa
  • Zfish genes xpa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Xpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	XPA	IDA		Human	PMID:7700386
Molecular Function	GO:0003676	nucleic acid binding	XPA	EXP		Human	PMID:10050037
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q9HCS7	Human	PMID:10944529
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:10982866
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:11058119
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:12527904
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:16491090
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:17948053
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:O95714	Human	PMID:20304803
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:20304803
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:20670893
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q96EB6	Human	PMID:20670893
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q9GZM8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:O14972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:O15079	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:O15160	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P12757	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q99856	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q9GZM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q9P0N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P15927	Human	PMID:7700386
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P27694	Human	PMID:7700386
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:8197175
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:Q03468	Human	PMID:8999876
Molecular Function	GO:0005515	protein binding	XPA	IPI	UniProtKB:P07992	Human	PMID:9013642
Molecular Function	GO:0019904	protein domain specific binding	XPA	IPI	UniProtKB:P07992	Human	PMID:17720715
Molecular Function	GO:0042803	protein homodimerization activity	XPA	IPI	UniProtKB:P23025	Human	PMID:8197175
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	XPA	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Xpa	IDA		Rat	PMID:23022597|RGD:9590340
Cellular Component	GO:0045171	intercellular bridge	XPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	XPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	XPA	IDA		Human	PMID:1601884
Cellular Component	GO:0005634	nucleus	Xpa	IDA		Mouse	PMID:12815074
Cellular Component	GO:0005634	nucleus	Xpa	IDA		Rat	PMID:18543291|RGD:9590336
Cellular Component	GO:0005634	nucleus	Xpa	IDA		Rat	PMID:23022597|RGD:9590340
Biological Process	GO:0006281	DNA repair	XPA	IDA		Human	PMID:1601884
Biological Process	GO:0006281	DNA repair	XPA	IMP		Human	PMID:1601884
Biological Process	GO:0006281	DNA repair	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:9661901
Biological Process	GO:0006281	DNA repair	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:11950998
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:11005836
Biological Process	GO:0035264	multicellular organism growth	Xpa	IGI	MGI:MGI:95412	Mouse	PMID:22323595
Biological Process	GO:0006289	nucleotide-excision repair	XPA	IMP		Human	PMID:21148310
Biological Process	GO:0006289	nucleotide-excision repair	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:11950998
Biological Process	GO:0006289	nucleotide-excision repair	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:12509265
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	Xpa	IGI	MGI:MGI:1100494	Mouse	PMID:22323595
Biological Process	GO:0034504	protein localization to nucleus	XPA	IMP		Human	PMID:1601884
Biological Process	GO:0010506	regulation of autophagy	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:18443001
Biological Process	GO:0010996	response to auditory stimulus	Xpa	IEP		Rat	PMID:23022597|RGD:9590340
Biological Process	GO:0006979	response to oxidative stress	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:11950998
Biological Process	GO:0006979	response to oxidative stress	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:12509265
Biological Process	GO:0009636	response to toxic substance	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:11408355
Biological Process	GO:0009411	response to UV	Xpa	IMP	MGI:MGI:1857939	Mouse	PMID:10843671
Biological Process	GO:0009650	UV protection	XPA	IDA		Human	PMID:1601884
Biological Process	GO:0009650	UV protection	XPA	IMP		Human	PMID:1601884

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern