Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Yes1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes YES1
- Mouse genes Yes1
- Rat genes Yes1
- Zfish genes yes1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Yes1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	YES1	IPI	UniProtKB:O95573	Human	PMID:20605918
Molecular Function	GO:0005154	epidermal growth factor receptor binding	Yes1	IPI	RGD:2543	Rat	PMID:21037565\|RGD:5131516
Molecular Function	GO:0001784	phosphotyrosine residue binding	YES1	IPI	UniProtKB:Q6GX35	Human	PMID:20624904
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9H204	Human	PMID:16964398
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9H5V8	Human	PMID:21233420
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P25445-1	Human	PMID:21713032
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9H5V8	Human	PMID:21725358
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q05397	Human	PMID:23397142
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P00533	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P09917	Human	PMID:24860872
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O14672	Human	PMID:25036101
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:I6L996	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O14543	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q6P1W5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8IVP5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96BR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9BWW4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9GZT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9Y4K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P40189	Human	PMID:25731159
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8TAK6	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q16543	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8IVP5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q16543	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:I6L996	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O14508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O14512	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O14543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O43281-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O60496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P14136	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P17661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P46109	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P49023-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P51114-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P51116	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P56945	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q13191	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q14847-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q15428	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q16630-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q68D51-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q7Z4V0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8IYX8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q8TD16-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q92569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96BR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96GY0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96N16	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q96Q35-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9BWW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9C035-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9HD42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9NR46	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9NUP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9NVV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9UGK3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9UKT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9ULV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9Y4K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9Y592-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:P56945	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q05397	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q12774	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9BXM0	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	YES1	IPI	UniProtKB:Q9ULH1	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Yes1	IPI	PR:Q61614	Mouse	PMID:11546805
Molecular Function	GO:0005515	protein binding	Yes1	IPI	PR:P46938	Mouse	PMID:21385842
Molecular Function	GO:0005515	protein binding	Yes1	IPI	PR:Q8BWG8	Mouse	PMID:11546805
Molecular Function	GO:0005515	protein binding	Yes1	IPI	PR:Q04736	Mouse	PMID:11546805
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:10861086
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:11448999
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:12923167
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:1381360
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:16921024
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:18697750
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	IDA		Human	PMID:26979622
Molecular Function	GO:0004713	protein tyrosine kinase activity	YES1	EXP		Human	PMID:9799234
Molecular Function	GO:0004713	protein tyrosine kinase activity	Yes1	IDA		Mouse	MGI:MGI:5807022\|PMID:26979622
Molecular Function	GO:0004713	protein tyrosine kinase activity	Yes1	IDA		Rat	PMID:9058199\|RGD:634514
Molecular Function	GO:0004713	protein tyrosine kinase activity	yes1	IDA		Zfish	PMID:15572145
Molecular Function	GO:0044325	transmembrane transporter binding	YES1	IPI	UniProtKB:Q9HBA0	Human	PMID:12538589
Cellular Component	GO:0005884	actin filament	Yes1	IDA		Mouse	PMID:17623777
Cellular Component	GO:0005829	cytosol	YES1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	YES1	HDA		Human	PMID:19199708
Cellular Component	GO:0005925	focal adhesion	YES1	HDA		Human	PMID:21423176
Cellular Component	GO:0098978	glutamatergic synapse	Yes1	IDA		Rat	PMID:14529711\|RGD:2303716
Cellular Component	GO:0005794	Golgi apparatus	YES1	IDA		Human	PMID:20605918
Cellular Component	GO:0005886	plasma membrane	YES1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	YES1	IDA		Human	PMID:20605918
Cellular Component	GO:0005886	plasma membrane	Yes1	IDA		Mouse	PMID:17623777
Cellular Component	GO:0005886	plasma membrane	Yes1	IDA		Rat	PMID:9058199\|RGD:634514
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	Yes1	IDA		Rat	PMID:14529711\|RGD:2303716
Biological Process	GO:0034334	adherens junction maintenance	yes1	IGI	ZFIN:ZDB-GENE-030903-5	Zfish	PMID:26860872
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Yes1	IDA		Mouse	PMID:17623777
Biological Process	GO:0071300	cellular response to retinoic acid	Yes1	IDA		Mouse	PMID:21385842
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Yes1	IGI	MGI:MGI:98397	Mouse	PMID:21829547
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Yes1	IGI	MGI:MGI:95602	Mouse	PMID:21829547
Biological Process	GO:0060027	convergent extension involved in gastrulation	yes1	IGI	ZFIN:ZDB-MRPHLNO-041217-10,ZFIN:ZDB-MRPHLNO-050128-3,ZFIN:ZDB-MRPHLNO-070304-3	Zfish	PMID:15815683
Biological Process	GO:0060027	convergent extension involved in gastrulation	yes1	IGI	ZFIN:ZDB-MRPHLNO-041217-11,ZFIN:ZDB-MRPHLNO-050128-3,ZFIN:ZDB-MRPHLNO-070304-3	Zfish	PMID:15815683
Biological Process	GO:0060027	convergent extension involved in gastrulation	yes1	IGI	ZFIN:ZDB-MRPHLNO-050128-3,ZFIN:ZDB-MRPHLNO-070304-3	Zfish	PMID:15815683
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Yes1	IDA		Mouse	PMID:21385842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Yes1	IGI	MGI:MGI:104904	Mouse	PMID:21385842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Yes1	IGI	MGI:MGI:96787	Mouse	PMID:21385842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Yes1	IGI	MGI:MGI:103262	Mouse	PMID:21385842
Biological Process	GO:0046777	protein autophosphorylation	Yes1	IDA		Rat	PMID:9058199\|RGD:634514
Biological Process	GO:0046777	protein autophosphorylation	yes1	IDA		Zfish	PMID:15572145
Biological Process	GO:0010827	regulation of glucose transmembrane transport	Yes1	IDA		Mouse	PMID:11546805
Biological Process	GO:0045859	regulation of protein kinase activity	yes1	IGI	ZFIN:ZDB-MRPHLNO-050128-3,ZFIN:ZDB-MRPHLNO-070304-3	Zfish	PMID:17611617
Biological Process	GO:0045859	regulation of protein kinase activity	yes1	IGI	ZFIN:ZDB-MRPHLNO-050128-3,ZFIN:ZDB-MRPHLNO-070304-3	Zfish	PMID:18550893

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.