Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YTHDC1
  • Mouse genes Ythdc1
  • Rat genes Ythdc1
  • Zfish genes ythdc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ythdc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDC1	IDA		Human	PMID:25242552
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDC1	IDA		Human	PMID:26318451
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDC1	IDA		Human	PMID:26876937
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDC1	IDA		Human	PMID:27602518
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDC1	IDA		Human	PMID:28984244
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	Ythdc1	IDA		Rat	PMID:25389274|RGD:10047201
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q91V33	Human	PMID:15345239
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P84586	Human	PMID:19282290
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P62995	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q96SB4	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:O75525	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P49760	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P61978	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q15415	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q5VWX1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q92997	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:O75494	Human	PMID:26876937
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P84103	Human	PMID:26876937
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P84103	Human	PMID:28984244
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P61978	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q9H190	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:O15084	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:O75525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P0DJD3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P49760	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P60371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P61978-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P62995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q15287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q15415	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q5T6S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q5VWX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	YTHDC1	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Ythdc1	IPI	UniProtKB:O88974	Mouse	MGI:MGI:6710177|PMID:33658714
Molecular Function	GO:0005515	protein binding	Ythdc1	IPI	UniProtKB:P84104|UniProtKB:Q6NVF9|UniProtKB:Q8BL97	Mouse	MGI:MGI:6161521|PMID:29799838
Molecular Function	GO:0005515	protein binding	Ythdc1	IPI	RGD:621459|RGD:620613|RGD:1562563	Rat	PMID:10564280|RGD:634512
Molecular Function	GO:0005515	protein binding	Ythdc1	IPI	RGD:1565256	Rat	PMID:19282290|RGD:2316827
Molecular Function	GO:0003723	RNA binding	YTHDC1	IDA		Human	PMID:20167602
Molecular Function	GO:0003723	RNA binding	YTHDC1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	YTHDC1	HDA		Human	PMID:22681889
Cellular Component	GO:0016604	nuclear body	Ythdc1	IDA		Rat	PMID:10564280|RGD:634512
Cellular Component	GO:0016607	nuclear speck	YTHDC1	IDA		Human	PMID:26876937
Cellular Component	GO:0005654	nucleoplasm	YTHDC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Ythdc1	IDA		Rat	PMID:10564280|RGD:634512
Cellular Component	GO:0005634	nucleus	YTHDC1	IDA		Human	PMID:20167602
Cellular Component	GO:0005634	nucleus	Ythdc1	IDA		Mouse	PMID:29799838
Cellular Component	GO:0005886	plasma membrane	YTHDC1	IDA		Human	GO_REF:0000052
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	YTHDC1	IDA		Human	PMID:27602518
Biological Process	GO:0001701	in utero embryonic development	Ythdc1	IMP	MGI:6194737	Mouse	PMID:29799838
Biological Process	GO:0110104	mRNA alternative polyadenylation	Ythdc1	IMP		Mouse	PMID:29799838
Biological Process	GO:0006406	mRNA export from nucleus	YTHDC1	IDA		Human	PMID:28984244
Biological Process	GO:0006376	mRNA splice site selection	YTHDC1	IDA		Human	PMID:20167602
Biological Process	GO:0000398	mRNA splicing, via spliceosome	Ythdc1	IDA		Rat	PMID:10564280|RGD:634512
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Ythdc1	IMP		Mouse	MGI:MGI:6114846|PMID:29262316
Biological Process	GO:0048160	primary follicle stage	Ythdc1	IMP	MGI:6194732,MGI:2176187	Mouse	PMID:29799838
Biological Process	GO:0048160	primary follicle stage	Ythdc1	IMP	MGI:6194732,MGI:3757577	Mouse	PMID:29799838
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Ythdc1	IMP		Mouse	PMID:29799838
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	YTHDC1	IDA		Human	PMID:26876937
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	YTHDC1	IDA		Human	PMID:28984244
Biological Process	GO:0007283	spermatogenesis	Ythdc1	IMP	MGI:6194732,MGI:3757577	Mouse	PMID:29799838

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern