Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YTHDF3
  • Mouse genes Ythdf3
  • Rat genes Ythdf3
  • Zfish genes ythdf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ythdf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:22575960
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:24284625
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:28106072
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:28106076
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:31292544
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:32451507
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF3	IDA		Human	PMID:32492408
Molecular Function	GO:0005515	protein binding	YTHDF3	IPI	UniProtKB:P04591:PRO_0000038596	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	YTHDF3	IPI	UniProtKB:Q9BYJ9	Human	PMID:28106072
Molecular Function	GO:0005515	protein binding	YTHDF3	IPI	UniProtKB:Q9Y5A9	Human	PMID:28106072
Molecular Function	GO:0005515	protein binding	YTHDF3	IPI	UniProtKB:Q9UNN5	Human	PMID:32296183
Molecular Function	GO:0043022	ribosome binding	YTHDF3	IDA		Human	PMID:28106076
Molecular Function	GO:0003723	RNA binding	YTHDF3	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	YTHDF3	IDA		Human	PMID:32194978
Cellular Component	GO:0005737	cytoplasm	YTHDF3	IDA		Human	PMID:32492408
Cellular Component	GO:0005737	cytoplasm	Ythdf3	IDA		Mouse	MGI:MGI:6490006|PMID:32943573
Cellular Component	GO:0010494	cytoplasmic stress granule	YTHDF3	IDA		Human	PMID:32451507
Cellular Component	GO:0000932	P-body	YTHDF3	IDA		Human	PMID:32492408
Biological Process	GO:0061157	mRNA destabilization	YTHDF3	IMP		Human	PMID:28106072
Biological Process	GO:0061157	mRNA destabilization	YTHDF3	IDA		Human	PMID:32492408
Biological Process	GO:0061157	mRNA destabilization	Ythdf3	IMP		Mouse	MGI:MGI:6490006|PMID:32943573
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	Ythdf3	IMP		Mouse	MGI:MGI:6316470|PMID:30591559
Biological Process	GO:0070925	organelle assembly	YTHDF3	IDA		Human	PMID:31292544
Biological Process	GO:0045727	positive regulation of translation	YTHDF3	IMP		Human	PMID:28106072
Biological Process	GO:0045948	positive regulation of translational initiation	YTHDF3	IDA		Human	PMID:28106076
Biological Process	GO:0043488	regulation of mRNA stability	YTHDF3	IMP		Human	PMID:32194978
Biological Process	GO:0043488	regulation of mRNA stability	YTHDF3	IDA		Human	PMID:32492408
Biological Process	GO:0043488	regulation of mRNA stability	Ythdf3	IMP		Mouse	MGI:MGI:6490006|PMID:32943573
Biological Process	GO:1901163	regulation of trophoblast cell migration	YTHDF3	IMP		Human	PMID:32194978
Biological Process	GO:0034063	stress granule assembly	YTHDF3	IDA		Human	PMID:32451507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern