Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YWHAB
  • Mouse genes Ywhab
  • Rat genes Ywhab
  • Zfish genes ywhaba,ywhabb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ywhab

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	YWHAB	HDA		Human	PMID:25468996
Molecular Function	GO:0019899	enzyme binding	YWHAB	IPI	UniProtKB:Q13370	Human	PMID:17255105
Molecular Function	GO:0042826	histone deacetylase binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:10869435
Molecular Function	GO:0042826	histone deacetylase binding	YWHAB	IPI	UniProtKB:Q9UQL6	Human	PMID:10869435
Molecular Function	GO:0042802	identical protein binding	YWHAB	IPI	UniProtKB:P31946	Human	PMID:17085597
Molecular Function	GO:0042802	identical protein binding	YWHAB	IPI	UniProtKB:P31946	Human	PMID:23622247
Molecular Function	GO:0051219	phosphoprotein binding	YWHAB	IPI	UniProtKB:Q9UQL6	Human	PMID:10869435
Molecular Function	GO:0050815	phosphoserine residue binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:10869435
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30305	Human	PMID:10713667
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:10958686
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22681	Human	PMID:11157475
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q63572	Human	PMID:11555644
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22681	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22893	Human	PMID:11886850
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P49815	Human	PMID:12582162
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P15056	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q16890	Human	PMID:12963375
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22893	Human	PMID:14688255
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P55040	Human	PMID:14701738
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P55041	Human	PMID:14701738
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q99759	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q99683	Human	PMID:15023544
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q8WYL5	Human	PMID:15159416
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P55041	Human	PMID:15860732
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q91YE8	Human	PMID:15883195
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:B7UM99	Human	PMID:16367866
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q11184	Human	PMID:16672054
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30305	Human	PMID:16672277
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:O94921	Human	PMID:16775625
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q9P0K1-3	Human	PMID:16868027
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27448	Human	PMID:16959763
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q7KZI7	Human	PMID:16959763
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27348	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P61981	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P62258	Human	PMID:17085597
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22893	Human	PMID:17170118
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q13627-2	Human	PMID:17229891
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q91YE8	Human	PMID:17923693
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P46937	Human	PMID:17974916
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q99759	Human	PMID:18308725
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q25C79	Human	PMID:18460465
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q96TC7	Human	PMID:18771726
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q9UQC2	Human	PMID:19172738
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q8WYL5	Human	PMID:19329994
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P46937	Human	PMID:19439659
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30307	Human	PMID:19470455
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P78362	Human	PMID:19592491
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:19595761
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q96PX8	Human	PMID:19640509
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P67828	Human	PMID:19860830
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q8VIP2	Human	PMID:20025850
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P46937	Human	PMID:20048001
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P49815	Human	PMID:20169078
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q5S007	Human	PMID:20642453
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P62258	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q12802	Human	PMID:21224381
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q9NYF0	Human	PMID:21262972
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22893	Human	PMID:21278420
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q99683	Human	PMID:21771788
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q92934	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q96TC7	Human	PMID:21972092
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:O00257	Human	PMID:22078878
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q76353	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q8WUA7	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q9NU19	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q9UBF8	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P61587	Human	PMID:23622247
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P61588	Human	PMID:23622247
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P15056	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P22681	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27348	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27448	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30307	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P46937	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P49815	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P61981	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P62258	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q7KZI7	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q92934	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P46937	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q5S007	Human	PMID:24510904
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q5S007	Human	PMID:24947832
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q6ZS17-2	Human	PMID:25588844
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30305	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:O15553	Human	PMID:27030597
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P26045	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30307	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P26045	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30304	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30307	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27348	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P55040	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P15056	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P62258	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q92934	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P15056	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P27448	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:Q7KZI7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:A0A0S2Z5Q7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P56524	Human	PMID:33537682
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30304	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P30305	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:7882972
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:7935795
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P04049	Human	PMID:8085158
Molecular Function	GO:0005515	protein binding	YWHAB	IPI	UniProtKB:P26045	Human	PMID:9341175
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:P16054	Mouse	MGI:MGI:5508583|PMID:19429675
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:P16054	Mouse	MGI:MGI:5306290|PMID:18604201
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:5487519|PMID:21390248
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:Q61337	Mouse	MGI:MGI:4453294|PMID:19915011
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:Q91YE8	Mouse	MGI:MGI:3583408|PMID:15883195
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:6355873|PMID:31046837
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:P16054	Mouse	MGI:MGI:5512837|PMID:18237277
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	PR:P48967	Mouse	PMID:12937170
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	PR:Q9EPK5	Mouse	PMID:16099986
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	UniProtKB:O92972:PRO_0000278742	Rat	PMID:10644344|RGD:10047359
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	RGD:1306565	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	RGD:620160|RGD:620103	Rat	PMID:12871587|RGD:2306032
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	RGD:1307791	Rat	PMID:18460465|RGD:2306009
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	RGD:70892	Rat	PMID:20629186|RGD:10045890
Molecular Function	GO:0005515	protein binding	Ywhab	IPI	RGD:1561609	Rat	PMID:21454690|RGD:7247577
Molecular Function	GO:0019904	protein domain specific binding	YWHAB	IPI	UniProtKB:Q99698	Human	PMID:11984006
Molecular Function	GO:0019904	protein domain specific binding	Ywhab	IDA		Mouse	PMID:12446771
Molecular Function	GO:0004860	protein kinase inhibitor activity	YWHAB	IDA		Human	PMID:11555644
Molecular Function	GO:0044877	protein-containing complex binding	Ywhab	IPI	RGD:1306431|RGD:68415	Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0005737	cytoplasm	YWHAB	IDA		Human	PMID:10869435
Cellular Component	GO:0005737	cytoplasm	YWHAB	IDA		Human	PMID:12963375
Cellular Component	GO:0005737	cytoplasm	Ywhab	IDA		Rat	PMID:18460465|RGD:2306009
Cellular Component	GO:0005829	cytosol	YWHAB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	YWHAB	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	YWHAB	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	YWHAB	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	YWHAB	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	Ywhab	IDA		Rat	PMID:18460465|RGD:2306009
Cellular Component	GO:0048471	perinuclear region of cytoplasm	YWHAB	IDA		Human	PMID:12963375
Cellular Component	GO:0032991	protein-containing complex	Ywhab	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0017053	transcription repressor complex	Ywhab	IDA		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0051220	cytoplasmic sequestering of protein	YWHAB	IDA		Human	PMID:10869435
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ywhab	IMP		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	YWHAB	IMP		Human	PMID:21224381
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	YWHAB	IDA		Human	PMID:17255105
Biological Process	GO:0006911	phagocytosis, engulfment	ywhaba	IMP	ZFIN:ZDB-MRPHLNO-120830-7	Zfish	PMID:21208897
Biological Process	GO:0006911	phagocytosis, engulfment	ywhaba	IMP	ZFIN:ZDB-MRPHLNO-120830-6	Zfish	PMID:21208897
Biological Process	GO:0043085	positive regulation of catalytic activity	YWHAB	IDA		Human	PMID:17255105
Biological Process	GO:0006605	protein targeting	Ywhab	IDA		Mouse	PMID:12446771

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern